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Contact Name
Dita Arccinirmala
Contact Email
dorotea.arccinirmala@kalbe.co.id
Phone
+6281905203065
Journal Mail Official
CDK@kalbe.co.id
Editorial Address
Redaksi CDK Gedung Kalbe, gedung 2 lantai 2 Jl. Letjen Suprapto Kav. 4. Cempaka Putih - Jakarta 10510
Location
Unknown,
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INDONESIA
Cermin Dunia Kedokteran
Published by PT. Kalbe Farma Tbk.
ISSN : 0125913X     EISSN : 25032720     DOI : 10.55175
Core Subject : Health,
Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK covers the disciplines of medicine, pharmacy, and health with several types of articles, namely: 1. Research 2. Literature review 3. Case report 4. Evidence-based case report (EBCR), systematic review 5. Other scientific articles Based on the SK Kemendikbudristek Nomor 152/E/KPT/2023, CDK has obtained Rank 4 (SINTA 4) for Scientific Journals.
Articles 12 Documents
Search results for , issue "Vol 45 No 12 (2018): Interna" : 12 Documents clear
Aldehyde-Low Endothelial Progenitor Cells in Ischemic Wound Repair, Regulated by SDF1/CXCR4 Dias Rima Sutiono; Candra Louis
Cermin Dunia Kedokteran Vol 45 No 12 (2018): Interna
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v45i12.689

Abstract

The incidence rate of both ischemic heart disease and ischemic stroke over the past decade has become a concern in the respect of global mortality rate. Ischemia is a condition of oxygen deprivation in the specific tissue which leads to loss of organ function. Regenerative medicine by using the endothelial progenitor cells (EPCs) show a great potential, especially the Alde-Low EPCs. The Alde-Low EPCs are regulated mainly by the chemo-attractant proteins of SDF1/CXCR4 which responsible for the cell migration and is regulated by the HIF2α. Further investigation and research on the correlation of SDF1/CXCR4 and the Alde-Low EPCs are needed. Peningkatan kejadian dan kematian akibat penyakit jantung iskemik dan stroke iskemik secara global pada beberapa dasawarsa telah menjadi perhatian. Upaya regenerasi menggunakan sel progenitor endothelial (EPCs) memperlihatkan potensi sangat tinggi, khususnya Alde-rendah EPCs. Alde-rendah EPCs diregulasi oleh protein kemoatraktan dari SDF1/CXCR4 yang bertanggung jawab untuk migrasi sel dan diregulasikan oleh HIF2α. Hubungan SDF1/CXCR4 dan Alde-rendah EPCs masih perlu diteliti lebih lanjut.
Peran Radiologi untuk Mendiagnosis Lipoblastomatosis Biddulth
Cermin Dunia Kedokteran Vol 45 No 12 (2018): Interna
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v45i12.690

Abstract

Lipoblastomatosis merupakan kasus jarang, berupa tumor jinak jaringan lunak mengandung komponen embrionik lemak putih, terdiri atas selsel adiposit dan lipoblas (adiposa immatur) yang menginvasi jaringan sekitarnya. Predileksi tersering pada anak-anak, di subkutis atau jaringan lunak lebih dalam di regio ekstremitas atas atau bawah. Pemeriksaan radiologi konvensional berfungsi membedakan massa jaringan lunak dari keterlibatan tulang atau tumor primer tulang. Modalitas radiologi lain adalah CT scan ataupun MRI, yang membantu mengevaluasi massa, juga menilai ekstensi massa ke jaringan sekitarnya. Pemeriksaan histopatologi diperlukan sebagai standar baku emas untuk diagnosis. Lipoblastomatosis is a benign rare soft tissue mass containing embryonic white fat of adipocytes and lipoblasts that invade adjacent structures. It mostly occurs in children with predilection in subcutanous or deeper structure of upper or lower extrimities. Conventional radiographs serves to distinguish soft tissue mass with bone involvement or bone primary tumors. Other radiological modalities, such as CT scan or MRI, assess mass extension into the surrounding tissue. Histopathological examination is required as diagnosis gold standard

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