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IPTEK The Journal for Technology and Science
Published by Institut Teknologi Sepuluh Nopember Surabaya
ISSN : 08534098     EISSN : 20882033     DOI : -
Core Subject : Science,
Computer Science & IT
IPTEK The Journal for Technology and Science (eISSN: 2088-2033; Print ISSN:0853-4098), is an academic journal on the issued related to natural science and technology. The journal initially published four issues every year, i.e. February, May, August, and November. From 2014, IPTEK the Journal for Technology and Science publish three times a year, they are in April, August and December in online version.
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Search results for , issue "Vol 31, No 3 (2020): In-Press" : 1 Documents clear
Kinetics study of cellulose nanocrystals modification using rarasaponins by Elovich equation Wijaya, Christian; Ismadji, Suryadi; Gunawan, Setiyo
IPTEK The Journal for Technology and Science Vol 31, No 3 (2020): In-Press
Publisher : IPTEK, LPPM, Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j20882033.v31i3.5595

Abstract

The modification of cellulose nanocrystals (CNCs) using rarasaponins (RSs) was carried out to enhancing the hydrophobicity of the CNCs. The RSs are a natural surfactant that has hydrophilic and hydrophobic sides. The linked RSs on the CNCs surface can be used to bond the hydrophobic drugs so that the modified CNCs can be applied as the hydrophobic drugs carrier in the medical field. The kinetics study was successfully carried out using the Elovich equation as the modeling equation. The Elovich equation fits the modification results well based on two parameters, i.e., the RSs/CNCs ratios and the times. The dispersion characteristics analysis was carried out to figure the enhancement of the hydrophobicity on the modified CNCs compared to the unmodified CNCs. According to the kinetics study and the dispersion characteristics analysis, the modification of CNCs using RSs could enhance CNCs utilization in the hydrophobic drug delivery system

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