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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 6 Documents
 1 
Search results for , issue " Vol 46, No 02 (2014)" : 6 Documents clear
Prognostic predictor at Pediatrics Intensive Care Unit (PICU) with Pediatric Risk of Mortality III (PRISM III) scores Roni Naning, Vita Susianawati Purnomo Suryantoro
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 46, No 02 (2014)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (319.94 KB) | DOI: 10.19106/JMedScie004602201403

Abstract

Various mortality prognostic scoring system are available for predicting mortality risk in PediatricIntensive Care Unit (PICU). The Pediatric Risk of Mortality III (PRISM III) scoring system is one ofthe main indicators used in the PICU. This study was conducted to evaluate the PRISM III asprognostic predictor in PICU. This was a cohort study involving 64 patients who admitted toPICU in Dr. Sardjito General Hospital, Yogyakarta and met inclusion and exclusion criteria. Theclinical state of patients were assessed and the PRISM III scores corresponding to the firs 24hours of hospitalization were calculated. Outcome analysis was defined either as death ordischarged from the hospital were recorded. Multivariate analysis was performed to find outindependent predictive factor that influence the outcome of death. The discriminative power ofthe model was calculated based on the receiver operator curve (ROC). The result showed thatmental status (relative risk/RR: 13.21; 95%CI: 1.18-14.80), White Blood Count/WBC (RR: 19.51;95%CI: 18.12-25.15) and Blood Urea Nitrogen/BUN (RR:22.87; 95%CI:1.85-28.20) were foundto be the main predictive factors of death in PICU. The cut off value of 51 of PRISM III scoreyielded the best sensitivity (83%) and specificity (69%). In conclusion, PRISM III score can beused as a prognostic predictor to determine the death risk of patients hospitalized at PICU.
Optimal time of administration of fentanyl in reducing hemodynamic response in endotracheal intubation Sri Rahardjo, Guntur Muhammad Taqwin Gusti Ngurah Artika
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 46, No 02 (2014)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (591.348 KB) | DOI: 10.19106/JMedScie004602201404

Abstract

Laryngoscopy and endotracheal intubations are frequently conducted in general anesthesia.However, it can stimulate symphatic and sympatoadrenal activities. Several non andpharmacological interventions have been used to reduce the symphatic stimulation. Fentanyl isone of the opioid drugs that frequently used to decrease the cardiovascular responses after theintubations. In order to obtain an optimal effect, fentanyl should be administered in appropriatetime. This study was conducted to compare the time of fentanyl administration at 2, 5 and 7minutes before endotracheal intubation to reduce hemodynamic responses. This was anobervational study with a prospective cohort design on patients who were going to undergoelective sugical using general anesthesia followed laryngoscopy intubation in Dr Sardjito GeneralHospital and met the inclusion and exclusion criteria. The patients were then divided into 3groups i.e patients who received fentanyl 1.5 μg/kg body weight (BW) intravenously (IV) 2minutes (Group A), 5 minutes (Group B) and 7 minutes (Group C) before laryngoscopy intubations.The hemodynmic responses including sistolic and diastolic blood pressure (SBP and DBP), meanarterial pressure (MAP), heart rate (HR) and rate pressure product (RPP) were monitored andrecorded every 1 minute during 7 minutes period. The result showed that fentanyl administration5 minutes before laryngeal intubation was more effective in the decrease hemodynamic responsethat those 2 and 7 minutes. Significantly different in SBP in 2, 3, 4 and 7 minutes observationswas observed (p<0.05). Furthermore, significantly different in MAP in 2, 3 and 4 minutesobservation and in RPP in 1, 2, 3, 4 and 7 minute observation were also observed (p<0.05). Nosignificantly different was observed in HR during observation (p>0.05). In conclusion, theadministration of fentanyl 1.5 μg/kg BW IV at 5 minutes before intubation is more effectiveagainst hemodynamic responses in endotracheal intubation.
Symptoms of depression and quality of life in functional dyspepsia patients Agus Siswanto, Muhammad Eko Cahyanto Neneng Ratnasari
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 46, No 02 (2014)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (466.517 KB) | DOI: 10.19106/JMedScie.004602201405

Abstract

Dyspepsia is a common disorder characterized by heartburn, nausea, vomiting, bloating, feelingof fullness or early satiety, and belching. Functional dyspepsia (FD) or non-ulcer dyspepsia is asyndrome without any physical or endoscopic abnormalities underlying these symptoms. Theimpacts of FD on psychological disturbances and quality of life in patients have been postulated.However, it has not much been a concern. This study was conducted to evaluate the relationshipbetween symptoms of depression and quality of life in patients with FD. This was an observationalstudy with cross-sectional design involving 30 patients. The symptoms of depression weremeasured by beck depression inventory (BDI) and the quality of life of patients were measuredby SF-36. The results showed that FD were more suffered consecutively by female patients(66.7%), age over 45 years (53.4%), housewives (56.6%), educated graduates (56.6%) andmarried (90.0%). Moreover, patients who experienced symptoms of clinical depression withlow, moderate and severe levels were 16.3%, 33.3% dan 10.0%, respectively. A significantcorrelation between depressive symptoms and the overall of patients quality of life was observed(r = 0.481; p<0.05). Furthermore analysis showed that among eight domains of health in SF-36analyzed, a negative significant correlation was observed between the depressive symptoms andthe three domains of health i.e. general physical function, limitation of motion caused byphysical problems, and vitality. In conclusion, there is a negative correlation between depressivesymptoms and quality of life in patients with FD.
Serum calcium ions, ratio of calcium/ creatinine urine and bone mass density in perimenopausal and postmenopausal women Harjo Mulyono, Riswan Hadi Kusuma Windarwati
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 46, No 02 (2014)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (484.242 KB) | DOI: 10.19106/JMedScie004602201402

Abstract

Early diagnosis of osteoporosis is important to take early prevention and treatment. Dual energyX-ray absorbtiometry (DEXA) scan is gold standard diagnosis of osteoporosis. However, it ishigh technology and high cost. Biochemical marker using calcium could be developed for diagnosisof osteoporosis. The study was conducted to evaluate the correlation between serum calciumions level as well as urine calcium and urine creatinine (UCa/UCr) ratio and Bone Mineral Density(BMD) in perimenopausal and postmenopausal women. This was an observational study withcross-sectional design involving women aged 45-75 years who fulfilled the inclusion and exclusioncriteria. Bone Mineral Density was measured using DEXA method. Serum and urine calcium ionswere measured using ISE method, while serum and urine creatinine were determined using Jaffemethod. Ratio of UCa/UCr were then calculated. The correlation between serum calcium ions aswell as the ratio UCa/UCr and BMD of subjects were then analyzed. A total 63 subjects wereinvolved in this study consists of 21 normal subjects, 22 subjects with osteopenia and 20subjects with osteoporosis. Negative correlation between BMD and age (r=-0.591; p=0.001)and positive correlation between BMD and body mass index (BMI) (r=0.432; p=0.001) wereobserved. No correlation between serum calcium ions and BMD (r= -0.145; p=0.258), howevernegative correlation between UCa/UCr ratio and BMD (r=-0.310; p=0.013) were reported.Furthermore, no correlation was found between serum calcium ions and lumbar BMD (r=0.036;p=0.778), while negative correlation was found between UCa/UCr ratio and lumbar BMD (r= -0.414; p=0.001). In conclusion, there is no correlation between serum calcium ions levels andBMD, however there is a weak negative correlation between UCa/UCr ratio and BMD
Hygiene, sanitation and the soil transmitted helminths (STH) infection among elementary school students in West Lombok Sri Sumarni, Rahmawati Soeyoko
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 46, No 02 (2014)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (759.922 KB) | DOI: 10.19106/JMedScie004602201406

Abstract

The prevalenses of soil transmitted helminths (STH) infection in Lombok are relatively high. It isclosley associated with poor environmetal hygiene, non healthy sanitation status, poverty andimproper health services. The highest prevalences is normally observed in elementary school children.The aim of this study was to evalaute the relationship between hygiene, sanitation and STH infectionamong elementary school children in West Lombok. An observational study with cross-sectionaldesign was performed involving 197 elementary school children in Terong Tawah Village, LabuapiSub District, West Lombok District and 197 children in Ampenan, Mataram City as control. Thestool specimen of the children were collected and processed using Kato-Katz technique. Hygieneand sanitation of each subject that consisted nail hygiene, hand washing, using footwear, latrine,clean water availability, house floor, soil around the house were taken by questionnaire and directobservation. The result showed that the prevalences of STH among elementary school children inTerong Tawah (81.7%) was higher than that in Ampenan (12.7%).Trichuris trichiura was thepredominant helminth both in Terong Tawah (36.0%) and Ampenan (7.0%) followed by A.lumbricoides (20.4% in Terong Tawah and 4.5% in Ampenan). The mix infections between T.trichiura and A. lumbricoides among the children in Terong Tawah (24.4%) and Ampenan (1.0%)were also found. A significant relationship between hygiene and sanitaion i.e. nail cleaniness, washinghands, contaminated soil around the house and STH infection among elementary school children inTerong Tawah and Ampenan (p<0.05). In conclusion, there is a significant relationship betweenpersonal hygiene, environmental sanitation and STH infections among elementary school children.
The leucocytes, neutrophils and superoxydes dismutase (SOD) level after consuming guava juice (Psidium guajava L) during aerobic exercise for beginners Zaenal Muttaqien Sofro, Yuliana Noor Setiawati Ulvie Wiryatun Lestariana
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 46, No 02 (2014)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (812.253 KB) | DOI: 10.19106/JMedScie004602201401

Abstract

Physical exercise is important in preventing and adjunctive therapy certain diseases. However,over physical exercise for beginners may cause oxidative stress and muscle injury leads to generatechemoattractants whic enables to attract neutrophil and monocyte towards the injury and stimulatesleucocytes activation. The use of antioxidant-rich fruits to mitigate exercise induced oxidative stresshas been applied. This study was conducted to evaluate the effect of guava juice (Psidium guajavaL) consumption during aerobic exercise on leucocytes, neutrophils and superoxydes dismutase(SOD) level of beginners. Sixteen students of National Land College (Sekolah Tinggi PertanahanNasional/STPN), Yogyakarta who met the inclusion and exclusion criteria were involved in thisstudy. Subjects were divided into two groups i.e. a group given mineral water as control andanother group given 240 mL guava juice 0.67 g/mL daily for 27 days as treatment group. Bothgroups then underwent aerobic exercise for 30 minutes every day for 27 days. Blood samples weretaken before and after exercise on day 1, 7 and 14 for leucocyte and nutrophil count as well as SODanalysis. The leucocyte count and SOD level before and after exercise in both Guava juice andMineral water groups were not significantly different (p>0.05). However, the percentage of neutrophilon day 1 and 7 were significantly higher than that in Mineral water group (p<0.05). Moreover,during the exercise, the percentage of neutrophils in Guava juice group significantly increased(p<0.05), whereas in Mineral water group was not significantly different (p>0.05). It can beconcluded that consuming guava juice during exercise for the beginners does not influence leucocytecount and SOD levels. However, it can increase percentage of neutrophil.

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