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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Core Subject : Science,
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Articles 14 Documents
Search results for , issue "Vol 39, No 04 (2007)" : 14 Documents clear
The effect of cyperus rotundus root ethanol extract on the epithelization in the healing process on skin excision wound Ch. Tri Nuryana E. Suryadi Harijadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 39, No 04 (2007)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Ch. Tri Nuryana, E. Suryadi & Harijadi - The Influence of Ethanol Extract of Purple Nutsedge (Cyperusrotundus) on Epithelization of Skin Wound Healing ProcessBackground: If skin is wounded, epithelial cells will migrate to the wound area in order to keep homeostatic.Epithelization consists of mitotic and proliferation of epithelial cells. Rhizome of purple nutsedge (Cyperusrotundus) contains cyperene, flavonoid, ²-sitosterol dan ascorbic acid that can accelerate epithelization inwound healing process and has been used in traditional medicine.Objective: To investigate the influence of ethanol extract of Purple Nutsedge (Cyperus rotundus) inepithelization of wound healing process.Methods: Fourty five Balb/c male mice 8-10 weeks old, 25-35 g weight, were excised punch biopsy onback 0.5 cm right and left of columna vertebralis, 2.5 cm in cutis from the ear area. The mice weredivided into 5 groups. Negative control group was treated with vehicle of extract, positive control groupwas treated by gel containing placenta extract 1% & neomycin sulfate 0.5% and the others were treatedwith C. rotundus 1%, 2%, and 4% in concentration. Each of the groups was divided into 3 subgroups.Each of the subgroups composed of 3 mice based on the period of termination, i.e.: 3rd, 7th and 12th dayafter wounded. Histological evaluation was done to investigate the thickness of epithelial layer.Results: The data were analyzed by Two-way Anova and the results showed that there was a significantdifference (p<0.05) in every decapitation period, groups, and interaction between decapitation period andgroups. The results of LSD test showed that there was a significant difference (p<0.05) in the thicknessof epithelial layer between negative control and C. rotundus groups.Conclusion: Cyperus rotundus extract accelerates epithelization process of wound healing in mice.Key words: Wound healing - Cyperus rotundus - epithelization - mice
Exclusive breastfeeding and risk of atopic dermatitis in high risk infant Martaviani Budiastuti, Setya Wandita, Sumadiono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 39, No 04 (2007)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: WHO recommends exclusive breast-feeding for 6 months becaase it is highly beneficial. It hasbeen proven by a number of studies to be advantageous in preventing various infectious diseases. However,its role in preventing allergic diseases especially atopic dermatitis in infant remains uncertain until recently.Objective: To find out whether high risk infant who did not receive exclusive breast-feeding would have agreater risk to suffer from atopic dermatitis.Method: We conducted a case-control study. Data were obtained from Pediatric Outpatient Clinics andDermatology and Venerology Outpatient Clinics, Dr. Sardjito Hospital Yogyakarta. Case group was highrisk infants with atopic dermatitis, while control group was high risk infants but not having the disease.Statistical analysis used Chi-square and degree of significance was stated as Confidence Interval (CI) of95% for each Odds Ratio (OR). Multivariate analysis was performed by using logistic regression method.Results: The study included 88 subjects with 44 subjects for case and control groupas well Logisticregression showed that not receiving exclusive breast-feeding was statistically significant risk factor toatopic dermatitis in high risk infant {OR 3.72 (95% CI: 1.40-9.90); p 0.01}.Conclusion: High risk infant not receiving exclusive breast-feeding will have greater risk to develop atopicdermatitis.Keywords: exclusive breast-feeding, atopic dermatitis; high risk infants.
Preliminary study on congenital anomaly in DR. Sardjito General Hospital Yogyakarta M. Mansyur Romi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 39, No 04 (2007)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Congenital anomalies and genetic diseases tend to increase and dominate hospital admittance,especially in the pediatric wards in developed countries. The spectrum of diseases in regions with lowinfant mortality rate is likely to go with such tendency It is necessary to study congenital anomalies andgenetic diseases at Dr. Sardjito General Hospital, locating in a region with much lower infant mortalityrate than that of the national average.Objective: To know the occurrence of congenital anomalies and its pattern among DR. Sardjito GeneralHospital in-patients.Method: An desricptive study was done on secondary data taken from data-base of the Hospital in 1998 –2002 period. All of admittances in that period diagnosed as primary or secondary diagnosis, with Q00 –Q99 congenital malformations, deformations, and chromosomal abnormalities according to InternationalClassisifaction of Diseases (ICD), were included. The pattern of anomaly at the Hospital was compared tothat of different population and period.Results: There were 1968 1070 males and 898 females) admittances with congenital anomalies at Dr.Sardjito General Hospital in 1998 – 2002. The proportion compared to the whole admittance was 2.06%.The most prevalent was Q35 – Q37 cleft lip and cleft palate (21.14%), followed by Q38 – Q45 othercongenital malformations of the digestive system (18.45%), Q20 – Q28 malformations of the circulatorysystem (15.65%), Q50 – Q56 malformations of genital organs (12,55%), Q00 – Q07 malformations ofthe nervous system (11.89%), Q65-Q79: malformations nd deformations of musculoskeletal system(6.40%), Q80-Q89: other congenital malformations (4.06%), Q10-Q18: malformations of eye, ear, faceand neck (3,91%), Q60-Q64: malformations of the urinary system (2.54%), Q90-Q99: Chromosomalanomalies (2,44%), and Q30-Q34: malformations of the respiratory system (0.97%).Conclusion: Congenital anomalies at Dr. Sardjito General Hospital were dominated by cleft lip and palate,and other congenital malformations of the digestive system. The pattern was similar to that of otherregions of Indonesia, and differed from Indian and European populationsKey words: congenital anomalies – genetic diseases – malformations – Dr. Sardjito General Hospital
Somatotypes of children in different areas of Indonesia Rahmawati NT Hastuti J, Yevita N Ashizawa K
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 39, No 04 (2007)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Human populations consist of individuals who differ widely in body shape and size. Somatotypesare morpho-phenotypic ranges along continua of variation, which possess constantly recognizablecharacteristics and are the functional end products of the whole genetic and the developmental complex.Objective: The objective of this cross-sectional study was to establish the somatotypes of urban, agriculturaland fishing village children in Indonesia.Method: Anthropometric somatotypes of children are considered in a cross-sectional sample of schoolgoing,ranging in age from 7-15 years. A total numbers 1716 (816 boys and 900 girls) consist of childrenin urban Yogyakarta (340 boys and 371 girls), agricultural Bantul (222 boys and 243 girls), and fishingPadang (254 boys and 286 girls). Heath-Carter somatotypes were determined for all subjects.Result: The Yogyakarta children were taller and heavier than their agricultural and fishing counterparts inboth sexes. The Yogyakarta children (urban) were more endomorphic, mesomorphic, and less ectomorphicthan the Bantul and Padang children. The Padang children (fishing village) were more ectomorphic and lessendomorphic than the Yogyakarta and Bantul children. The mean somatotype of boys and girls were 3.8 –3.6 – 3.7 and 4.2 – 3.1 – 3.6 (in urban city, respectively), 2.8 – 3.2 – 4.1 and 3.5 – 2.9 – 3.9 (in anagricultural village, respectively), and 2.5 – 3.5 – 3.8 and 3.5 – 3.1 – 3.5 (in fishing village, respectively).Conclusion: The finding indicated among the Indonesian children, the distribution of somatotype accordingto age was different between urban Yogyakarta, agricultural Bantul and fishing Padang. In general, thewell-off children were more endomorphic, and the low-income children were more ectomorphic.Key words: somatotype anthropometric – urban, agricultural, and fishing village children

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