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Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
ISSN : 23388404     EISSN : 26572311     DOI : -
Core Subject : Health,
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) is published twice a year, containing research articles, review, and short communication in pharmacy science field, including medicinal chemistry, analytical chemistry, biologjcal pharmacy, pharmaceutical sciences and clinical pharmacy research and practice of pharmacy in industry, clinic, and community practice, such as pharmacies, distributors, and pharmacy education.
Arjuna Subject : -
Articles 14 Documents
Search results for , issue "Vol 2, No 1 (2015)" : 14 Documents clear
Pembibitan Tanaman Purwoceng (Pimpinella pruatjan Molk) dengan Abu Vulkanik Sudrajad, Heru; Suharto, .; Fauzi, .
Jurnal Farmasi Sains dan Terapan Vol 2, No 1 (2015)
Publisher : Jurnal Farmasi Sains dan Terapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (255.042 KB) | DOI: 10.33508/jfst.v2i1.696

Abstract

Purwoceng (Pimpinella pruatjan Molk) represents one of the plantation medicines of Indonesia, which its population was almost extinction (endangered). Purwoceng represent the original plant of Indonesia with the swampy forest limited so that need special effort to preserve. Purwoceng represents the endemic species which was growing in the mountain with the height of 1.800-3.500 m dpl in West Java (Pangrango Mountain), Central Java (Dieng plateau) and East Java. Purwoceng seeds represent the highly cost commodity, which is observed by a lot of jamu industry. Volcano dusty from Kelud mountain eruption on Thusday, 12 February 2014 diseminating widely and reach the region Yogyakarta, Central Java and West Java. The volcano dusty could give the fertility of land and plant. It became the good materials for media planting. This research was conducted in Medicinal Plant and Traditional Medicine Research and Development Centre with Complete Random Device Methods, by using the volcano dusty media of Kelud mountain with the treatment of giberelin 0 (control), 25, 50 and 75 ppm. The research showed that the purwoceng seed with the addition of giberelin 25 ppm gave the best result of growth, the average of total leaf was 6,7 pieces, the length of handle was 6,11 cm and the length of root was 11, 7 cm with the colour of leaf was yellow green at 3 month olds.
Pengaruh Jamu Anemia terhadap Fungsi Ginjal di Rumah Riset Jamu“Hortus Medicus” Tawangmangu Ardiyanto, Danang; Triyono, Agus; Nisa, Ulfatun
Jurnal Farmasi Sains dan Terapan Vol 2, No 1 (2015)
Publisher : Jurnal Farmasi Sains dan Terapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.635 KB) | DOI: 10.33508/jfst.v2i1.697

Abstract

The use of herbal medicine in the formal health care requires adequate scientific evidence especially on herbal safety data. The herb could be used for the treatment of anemia. The indicator for the safety of the herb was kidney function by measuring urea and creatinine. A clinical trial study with pre-post test designed was conducted at the Jamu Research Center "Hortus Medicus" Tawangmangu to assess renal function of patients treated anemic with herbal formula for anemia. A total of 35 subjects volunteered to follow this study received therapy with herbal formula for 1 month. Formula was a herbal infusion made up of 5 grams of red amaranth leaves (Amaranthus tricolor L.), 10 grams herbs of tapak liman (Elephantopus scaber L.) and 15 grams of temulawak rhizome (Curcuma xanthorrhiza), taken 3 times a day. Kidney function was observed by measuring the levels of urea and creatinine subjects at baseline (D-0) and at day 28 (D-28). The results of t-test between urea levels in D-0 and D-28, showed the value of p = 0.942 (> 0.05) and creatinine levels in D-0 and D-28, p-value = 0.935 (> 0.05), which means no significant difference. It can be concluded that herbal formula for anemia did not affect renal function.
Efek Fraksi Air Daun Salam (Syzygium polyanthum) Terhadap Imunitas Alami Tikus Wistar Jantan Tamayanti, Wahyu Dewi; Soegianto, Lisa; Nurak, Elisabeth; Hadisoewignyo, Lannie; Ervina, Martha
Jurnal Farmasi Sains dan Terapan Vol 2, No 1 (2015)
Publisher : Jurnal Farmasi Sains dan Terapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4023.955 KB) | DOI: 10.33508/jfst.v2i1.702

Abstract

Pemberian fraksi air daun salam (Syzygium polyanthum) terhadap jumlah netrofil dan kadar IL-6 tjkus Wistarjantan yang telah diinduksi Staphylococcus aureus telah dilakukan. Tikus Wistar jantan dibagi dalam 3 ckelompok, masing-masing terdiri dari 5 ekor tikus, yaitu kelompok kontrol negatif (perlakuan NaCI 0,9%) kelompok uji (perlakuan fraksi air daun salam 200 mg/kg BB) dan ~elompok kontrol positif (perlakuan suspensi ibuprofen 400 mg/kg BB). Tikus dengan perlakuan dikorbankan satu jam setelah induksi Staphylococcus aureus, dan diambil darahnya. Perhitungan jumlah netrofil darah dilakukan .di bawah mikroskop dan penentuan kadar IL-6 dilakukan dengan metode ELISA. Hasil ana lisa data dengan anava satu arah mengindikasikan bahwa daun salam tidak menurunkan jumlah netrofil darah maupun IL-6 pada tikus Wistar jantan yang terinduksi Staphylococcus aureus.
Aktivitas Antihiperlipidemia Ekstrak Etanol Daun Annona squamosa L. Rofida, Siti; Firdiansyah, Ahmad; Fitriyastuti, Endah
Jurnal Farmasi Sains dan Terapan Vol 2, No 1 (2015)
Publisher : Jurnal Farmasi Sains dan Terapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (305.154 KB) | DOI: 10.33508/jfst.v2i1.693

Abstract

Cause of cardiovascular disease risk factors, one of which is a high cholesterol levels in serum. Mortality caused by cardiovascular disease as 17.3 million people. Annona squamosa L. or commonly referred custard apple is a plant from family Annonaceae and have been used for insecticide, antitumor, antidiabetic, antioxidant, anti-inflammatory, and antihyperlipidemia. The leaves of Annona squamosa L. contains acetogenin, diterpene, flavonoids, lignin, hydroxyl ketones, and benzoquinazolin. The aims of this study is to determine the optimum dose to reduce levels of LDL on hyperlipidemic rats. In this study, hyperlipidemic rats were divided into 5 groups, negative control group (normal feed), positive control group (normal feed and simvastatin at a dose of 0.9 mg/KgBW), treatment group 1 (normal feed and ethanol extract leaves of Annona squamosa L. at a dose of 0.25 mg/gBB, treatment groups 2 (normal feed and ethanol extract leaf of Annona squamosa L. at a dose of 0.75 mg/gBB, treatment groups 3 (normal feed and ethanol extract leaf of Annona squamosa L. at a dose of 1 mg/gBB). The results of identification by thin-layer chromatography on ethanol extract leaf of Annona squamosa L indicates the presence of flavonoids. The results showed that the ethanol extract leaves of Annona squamosa Linn. On hyperlipidemia rats, can lower LDL cholesterol levels at doses of 0.25 mg/gram BB.

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