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Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science)
Published by Universitas Ahmad Dahlan
ISSN : 14127946     EISSN : 25035223     DOI : 10.12928
Core Subject : Health, Science,
Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology
Media Farmasi is a scientific journal published by the University of Ahmad Dahlan worked closely with Ikatan Apoteker Indonesia (IAI). Media Farmasi published two times a year, namely in March and September since 2002 with ISSN 1412-7946 and e-ISSN 2503-5223. The article published in the Journal Media Farmasi selected by editors and reviewed by the reviewer. Articles published in Media Farmasi must not be published in other journals or have been previously published. Media Farmasi publishes a review article, original article, as well as short communication in all scopes of Pharmaceutical Science.
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Articles 11 Documents
 1   2 
Search results for , issue " Vol 12, No 1: Maret 2015" : 11 Documents clear
Uji Antihipertensi Infus Kombinasi Biji dan Rambut Jagung (Zea Mays L.) pada Tikus Jantan (Rattus norvegicus) dengan Metode Tail Cuff Non Invasive Herman, Hendra; Putra, Bayu
Media Farmasi: Jurnal Ilmu Farmasi Vol 12, No 1: Maret 2015
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (94.253 KB) | DOI: 10.12928/mf.v12i1.3027

Abstract

Penggunaan infus kombinasi biji dan rambut jagung sangat luas di masyarakat sehingga dilakukan penelitian yang bertujuan untuk mengetahui uji efek antihipetensi infus kombinasi biji dan rambut jagung (Zea mays L.) pada tikus jantan (Rattus norvegicus), menggunakan metode pengukuran tekanan darah Tail cuff non invasive. Tikus dibagi menjadi 3 kelompok perlakuan yaitu kelompok infus kombinasi rambut dan biji (50:50) dengan dosis 5 mg/gram, kelompok pembanding menggunakan Furosemid 45,75 mg/50 ml dan kelompok kontrolnegatif sebagai placebo. Tekanan darah sistol dan diastol diukur pada menit 30, 60 dan 120 setelah pemberian obat dengan menggunakan metode Tail cuff non invasive. Hasil penurunan tekanan darah kemudian dianalisis menggunakan metode Anova satu jalur dengan membandingkan pengaruh kelompok pelakuan terhadap penurunan tekanan darah tikus. Infus kombinasi biji dan rambut jagung(50:50) memberikan efek penurunan tekanan darah sistol yang sama dengan furosemid (p>0,05), tetapi memiliki efektifitas yang lebih besar terhadap penurunan tekanan darah diastol (p<0,05).Kata Kunci :Tekanan Darah, Rambut Jagung, Biji Jagung, Tail cuff non-invasive.

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