cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Tsania Faza
Contact Email
-
Phone
08111400115
Journal Mail Official
mji@ui.ac.id
Editorial Address
Education Tower 6th floor, IMERI building, Faculty of Medicine Universitas Indonesia, Jalan Salemba Raya 6, Jakarta, 10430, Indonesia
Location
Kota depok,
Jawa barat
INDONESIA
Medical Journal of Indonesia
Published by Universitas Indonesia
ISSN : 08531773     EISSN : 22528083     DOI : 10.13181
Core Subject : Health,
Medicine & Pharmacology
This quarterly medical journal is an official scientific journal of the Faculty of Medicine Universitas Indonesia in collaboration with German-Indonesian Medical Association (DIGM) Indexed in: IMSEAR; CAB Abstracts; Global Health; HINARI; DOAJ; DRJI; Google Scholar; JournalTOCs; Ulrichsweb Global Serial Directory; WorldCat; New Jour; Electronic Journals Library; ISJD Accredited (2013-2018) by DIKTI Kemendikbud Republik Indonesia (No:58/DIKTI/Kep/2013)
Arjuna Subject : -
Articles 11 Documents
 1   2 
Search results for , issue "Vol. 12 No. 2 (2003): April-June" : 11 Documents clear
The effect of potassium iodide on the production of acid phosphatase by Sporothrix schenckii
Medical Journal of Indonesia Vol. 12 No. 2 (2003): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i2.91

Abstract

The present study was undertaken to find out the in vitro effect of potassium iodide (KI) on the production of acid phosphatase by fully characterized strain of S.schenckii isolated from a patient of Cutaneous Sporotrichosis. The enzyme acid phosphatase was estimated during the 3 phases of growth of S.schenckii, without and with three concentrations of KI incorporated in the culture medium. In the control and in the test proper, with various concentrations of KI, no adverse effect of KI was observed on the production of acid phosphatase in early and mid log phase of fungal growth. Whereas in the exponential phase in test proper, there was a statistical significant decrease in the enzyme production with 0.8% and 3.2% of KI. The low activity at 0.8% and 3.2% KI indicates that KI has inhibitory effect on the growth of S.schenckii and has led to decrease in the activity of the enzyme. (Med J Indones 2003; 12: 65-8) Keywords: S.schenckii, acid phosphatase, potassium iodide
Long QT Syndrome - A case report
Medical Journal of Indonesia Vol. 12 No. 2 (2003): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i2.92

Abstract

Long QT syndrome (LQTS) is an uncommon disease due to genetic defect and responsible for polymorphic VT (torsade-de pointes-TdP) and sudden cardiac death. A case of 25 year-old woman with palpitation, severe headache and recurrent syncopal episode since 16 year-old is reported. The ECG showed bigeminy ventricular premaure contraction (VPC) , prolonged QTc interval and abnormal T wave. Peripartal cardiomyopathy was diagnosed recently after the first delivery. In July 2002, she was hospitalized due to recurrent syncope, seizure proceeded by TdP and VF. On admission she need several times DC shock and temporary pacemaker with relatively high rate. Beta-blocker and implantation of dual chamber permanent pacemaker finally could control the malignant arrhythmias. During follow-up for 4 months, she was doing well and no syncopal episode occurred. (Med J Indones 2003; 12: 109-13) Keywords: LQTS, arrhythmia, pacemaker, beta-blocker
Changes in temperature of newborn babies bathed immediately after birth
Medical Journal of Indonesia Vol. 12 No. 2 (2003): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i2.93

Abstract

In the tropics, bathing full-term newborn babies are routinely done immediately after birth, although it is usually not recommended until 2 - 6 hours of age. Yet, there is no study in Indonesia about hypothermia in newborns bathed immediately after birth. The aim of this study is to determine the influence of bathing the newborn immediately after birth to the body temperature and hypothermia. One hundred and twenty five healthy full-term newborn babies delivered on March 1999 were included and separated into two groups, 59 newborns were bathed immediately after birth and 66 newborns were bathed later. There was no statistical difference between both groups in the mean of birth weight, gestational age, room temperatures, gender, delivery method, and risk of infection. Mean body temperature between both groups were not statistically different on the 0 and the 30th minute after birth. On the other hand, on the 15th minute after birth, the mean body temperature of the immediately bathed group was statistically lower than not immediately bathed group [36.84 (SD 0.25)°C vs 37.02 (SD 0.27)°C, p=0.0001]. On the 15th minute after birth, there were four (6.8%) hypothermic babies (rectal temperature < 36.5°C) in the immediately bathed group and one (1.5%) hypothermic baby in the not immediately bathed group (p=0.134). Conclusion, bathing healthy full-term newborn babies immediately after birth will decrease the body temperature, but hypothermia occurred only in very small numbers which are not statistically significant. (Med J Indones 2003; 12: 73-79) Keywords: hypothermia, newborn baby, bathed immediately after birth
Diabetes mellitus in β-thalassemia major patients
Medical Journal of Indonesia Vol. 12 No. 2 (2003): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i2.94

Abstract

β-thalassemia major is a disease caused by β polypeptide chain synthesis disorder which is inherited as an autosomal recessive from both parents which is marked by little or no β globin chain synthesis. Medication for β thalassemia major patients is by repeated blood transfusions, which causes hemochromatosis. Hemochromatosis can occur in various organs including the pancreas. The aim of the study was to assess the alteration of plasma glucose concentration and the hemochromatosis prevalence. Fasting plasma glucose concentration and serum ferritin examination were measured in 115 β thalassemia major patients with ages between 10-23 years who were out-patients in the Thalassemia Centre, Department of Child Health, Medical School, University of Indonesia / Dr. Cipto Mangunkusumo General Hospital, Jakarta. The plasma glucose concentration examination was conducted by the GDH enzymatic method, with American Diabetes Association (ADA) criteria in the evaluation, while the serum ferritin examination was conducted with the microparticle enzyme immuno assay (MEIA) method. All patients had hemochromatosis, 14.8% of the patients had impaired fasting glucose level and 2.6% of the patients showed indications of diabetes mellitus. β thalassemia major patients who receive frequent transfusions will develop hemochromatosis that will in turn impair the pancreatic function. (Med J Indones 2003; 12: 87-93) Keywords : β thalassemia major, hemochromatosis, diabetes mellitus
Elastase-1 concentration in feces of term and preterm infants aged 0 - 4 months
Medical Journal of Indonesia Vol. 12 No. 2 (2003): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i2.95

Abstract

Fecal elastase-1 concentration reflects exocrine pancreatic function. There have been some reports from Europe, but so far there has not been a report of fecal elastase-1 concentration in Indonesia, especially concerning infants. The aim of this study is to know the concentration of elastase-1 in feces of infants aged 1-120 days as a preliminary report of the study of the ontogeny of pancreatic elastase-1 in term and preterm infants. Fecal elastase-1 were measured from feces of 28 healthy preterm and 34 healthy term infants up to 120 days (4 month) of age. Elastase-1 concentration in infants less than 14 days of age fluctuated below 200 μg/gram feces. At the first day of life 80% preterm and 60% term infants had elastase-1 concentration less than 200 μg/gram feces, and by the age of 7 days 50% preterm and 33% term infants had elastase-1 concentration less than 200 μg/gram feces. After 14 days of age its concentration was more than 200 μg/gram feces, regardless of gestational age. This preliminary study corroborates supported the previous studies that the level of fecal elastase-1 reached normal level after 14 days. Future longitudinal study is needed to know elastase-1 concentration in infants less than 14 days. (Med J Indones 2003; 12: 69-72) Keywords: Fecal elastase-1, Infants, Enzyme-link immunosorbent assay
Stress before and during pregnancy increased risk antepartum depression
Medical Journal of Indonesia Vol. 12 No. 2 (2003): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i2.96

Abstract

This paper presents the risk of antepartum depression (APD) among pregnant women. In particular stress before pregnancy, stress during pregnancy, marital relationship, social support, husband's mental status and monthly expenditure. The subjects consisted of 580 pregnant women in the third trimester, who attended antenatal care at the Department of Obstetrics of the Persahabatan Hospital Jakarta from November 1, 1999 to August 15, 2001. Antepartum depression was screened by a psychiatrist using the Edinburgh Postnatal Depression Scale (EPDS). Information on demographic and personal characteristics were collected from fill-in form. Through this form, the respondent gave information on stress before and during pregnancy, and from questionnaires Kuestioner Dukungan Sosial (KDS), Kesesuaian Hubungan Suami Istri (KHSI) and the Symptom Check List-90 (SCL-90) information about social support, marital relationship, and husband's mental status were collected respectively. The prevalence of APD was 18%. Antepartum depression and non-antepartum depression were similar in terms of age groups, level of education, occupations, monthly expenditures, number of pregnancies, number of children, number of deliveries, physical health condition, and history of premenstrual syndromes. Pregnant women with stress before pregnancy had a two-fold risk of APD [adjusted odds ratio (OR)=2.04; 95% confidence intervals (CI): 1.12-3.74] compared to pregnant women without stress before pregnancy. In addition, when compared to pregnant women without stress during pregnancy, those with stress during pregnancy had 2.2-fold risk of developing APD (adjusted OR=2.13, 95% CI: 1,27-3,74). In conclusion, stress before and during pregnancy increased the risk antepartum depression. Therefore, attention should be paid to pregnant women with these risk factors.
Surgical management of stage I and II vulvar cancer:The role of the separated incision
Medical Journal of Indonesia Vol. 12 No. 2 (2003): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i2.97

Abstract

Vulvar cancer is a gynecological cancer whose incidence rate is relatively low. Patients generally were admitted at advanced stage, and radiation therapy at advanced stage does not provide favorable prognosis. Two main modalities in the treatment of vulvar cancer are surgery and radiation therapy. However, radiation can be performed in early stage vulvar cancer but surgery is thought to have more benefits, such as in side effect on the ovary/ reproductive function disorder, patient's hygiene factor, and the ease in performing therapy if recurrence occurs. There are various techniques of vulvar cancer surgery, such as radical vulvectomy with butterfly incision (RVBI) and radical vulvectomy with separated incision (RVSI). The objective of this study was to identify the benefits of radical vulvectomy with separated incision in comparison with radical vulvectomy with butterfly incision in terms of the length of surgery, wound recovery, infection incidence, length of hospital stay. This study was a clinical trial performed during the period of 1990-2000. Fifteen cases of vulvar cancer were found and underwent surgery. Fourteen cases were at stage II and 14 cases were histologically defined as squamous-cell carcinoma and 1 case was adenocarcinoma. The average length of surgery in RVSI was 168 minutes, this was shorter than that in VRBI which reached an average of 275 minutes. The incidence of infection in RVSI group was 3 of 11 cases (27.27%), while in RVBI group all cases had infection in surgical wound. Failure of surgical wound approximation was 1 of 12 cases (9.99%), while in RVBI all cases experienced the failure such that cosmetic surgery was required. Length of postoperative care in RVSI group was 12.3 days, while in RVBI 21.5 days. Thus, complications in VRBI were lower, and length of surgery and length of postoperative care were shorter. (Med J Indones 2003; 12: 103-8) Keywords: vulvar cancer, separated incision
Surgical outcome of phacofragmentation and phacoemulsification in senile white mature cataract
Medical Journal of Indonesia Vol. 12 No. 2 (2003): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i2.98

Abstract

Purpose : To compare the effectiveness and safety of phacofragmentation and phacoemulsification techniques on senile white mature cataract. Methods : Prospective, double masked, randomized study comprises 32 eyes of senile white mature cataract randomly divided into 2 groups, 16 eyes had phacofragmentation (group I) and 16 eyes had phacoemulsification (group II). The evaluated safety parameters were pupil diameter pre surgery and prior to intra ocular lens (IOL) implantation, corneal thickness and flaremeter. Nucleus delivery, uncorrected visual acuity (UCVA) and surgically induced astigmatism (SIA) were the effectiveness parameters. Follow-up were scheduled for post-operative day 1,7,15 and 30. Results : prior to the surgery there were no significant differences in age, visual acuity, corneal thickness and flaremeter between two groups. Pre surgical and prior to IOL implantation mean pupilarry diameters in both groups were not significantly different. There was no significant difference in pupillary constriction on both groups. The mean of time to deliver the nucleus was significantly longer in the group II (4.38±2.51 min) than in the group I (1.98±1.61 min). There was significant difference on UCVA (p= 0.00067) and corneal thickness (p=0.0044) only on the first post-operative day. However, there was no significant difference on further evaluations (p>0.05). There were also no significant difference on flaremeter and SIA during follow -up. Conclusion : Both phacofragmentation and phacoemulsification techniques were effective and safe for cataract surgery on senile white mature cataract. Phacofragmentation technique therefore could be an alternative small incision cataract surgery. (Med J Indones 2003; 12: 94-102) Keywords : phacofragmentation, phacoemulsification, senile white mature cataract
Fixed Dose Combination for TB treatment
Medical Journal of Indonesia Vol. 12 No. 2 (2003): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i2.99

Abstract

According to the World Health Organization, a third of the world’s population is infected with tuberculosis. The disease is responsible for nearly 2 million deaths each year and over 8 million were developing active diseases. Moreover, according to WHO (2000), tuberculosis deaths are estimated to increase to 35 million between 2000-2020. The majority of tuberculosis patients worldwide are still treated with single drugs, or with 2-drug fixed-dose combinations (FDCs). To improve tuberculosis treatment, 2- and 3-drug FDCs were recommended by the World Health Organization (WHO) as part of the DOTS strategy. Since 1999 a 4-drug FDC was included on the WHO Model List of Essential Drugs. Today, FDCs are important tools to further improve the quality of care for people with TB, and accelerate DOTS expansion to reach the global TB control targets. Fixed dose combination TB drugs could simplifies both treatment and management of drug supply, and may prevent the emergence of drug resistance .Prevention of drug resistance is just one of the potential benefits of the use of FDCs. FDCs simplify administration of drugs by reducing the number of pills a patient takes each day and decreasing the risk of incorrect prescriptions. Most tuberculosis patients need only take 3–4 FDCs tablets per day during the intensive phase of treatment, instead of the 15–16 tablets per day that is common with single-drug formulations It is much simpler to explain to patients that they need to take four tablets of the same type and colour, rather than a mixture of tablets of different shapes, colours and sizes. Also, the chance of taking an incomplete combination of drugs is eliminated, since the four essential drugs are combined into one tablet. FDCs are also simpler for care-givers as they minimize the risk of confusion. Finally, drug procurement, in all its components (stock management, shipping, distribution), is simplified by FDCs. Adverse reactions to drugs are not more common if FDCs are used. Nevertheless, whenever side-effects to one or more components in a FDC are suspected, there will be a need to switch to single-drug formulations. Quality, safety and efficacy of FDC drugs are determined by the manufacturing process i.e. by compliance of the manufacturer with the requirements of good manufacturing practices (GMP) and pharmacopoeial specifications. National TB programmes must establish a QA system WHO established a laboratory network that tests the quality of FDCs in the marketplace and registers products upon request from the pharmaceutical industry. (Med J Indones 2003; 12: 114-9) Keywords: fixed dose combination, tuberculosis, treatment
Organophosphate poisoning : A review
Medical Journal of Indonesia Vol. 12 No. 2 (2003): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i2.100

Abstract

Organophosphate pesticides are used extensively worldwide, and poisoning by these agents, particularly in developing nations is a public health problem. Organophosphorous nerve agents are still considered as potential threat in both military or terrorism situations. The mechanism of toxicity is the inhibition of acetylcholinesterase, resulting in accumulation of the neurotransmitter acetylcholine and continued stimulation of acetylcholine receptors both in central and peripheral nervous systems. Beside acute cholinergic crisis, organophosphates are capable of producing several subacute or chronic neurological syndromes. The well described intermediate syndrome (IMS) emerges 1-4 days after an apparently well treated cholinergic crisis. The standard treatment consists of reactivation of inhibited acetylcholinesterase with an oxime antidote (pralidoxime, obidoxime, HI-6 and Hlo7) and reversal of the biochemical effects of acetylcholine with atropine. The newer oximes HI-6 and Hlo& are much more suitable and efficacious acetylcholinesterase reactivator for severe acute nerve agent induced poisoning than currently used pralidoxime or obidoxime. Patients who receive treatment promptly usually recover from acute toxicity but may suffer from neurologic sequelae. (Med J Indones 2003; 12: 120-6) Keywords: poisoning, insecticide, organophosphate (OP), carbamates, acetylcholinesterase, oxime, pralidoxime, obidoxime, HI-6, HLo7

Page 1 of 2 | Total Record : 11

 1   2 

Filter by Year

2003 2003


Reset
Filter By Issues
All Issue Vol. 34 No. 3 (2025): September Vol. 34 No. 2 (2025): June Vol. 34 No. 1 (2025): March Online First Vol. 33 No. 4 (2024): December Vol. 33 No. 3 (2024): September Vol. 33 No. 2 (2024): June Vol. 33 No. 1 (2024): March Vol. 32 No. 4 (2023): December Vol. 32 No. 3 (2023): September Vol. 32 No. 2 (2023): June Vol. 32 No. 1 (2023): March Vol. 31 No. 4 (2022): December Vol. 31 No. 3 (2022): September Vol. 31 No. 2 (2022): June Vol. 31 No. 1 (2022): March Vol. 30 No. 4 (2021): December Vol. 30 No. 3 (2021): September Vol. 30 No. 2 (2021): June Vol. 30 No. 1 (2021): March Vol. 29 No. 4 (2020): December Vol. 29 No. 3 (2020): September Vol. 29 No. 2 (2020): June Vol. 29 No. 1 (2020): March Vol. 28 No. 4 (2019): December Vol. 28 No. 3 (2019): September Vol. 28 No. 2 (2019): June Vol. 28 No. 1 (2019): March Vol. 27 No. 4 (2018): December Vol. 27 No. 3 (2018): September Vol. 27 No. 2 (2018): June Vol. 27 No. 1 (2018): March Vol. 26 No. 4 (2017): December Vol. 26 No. 3 (2017): September Vol. 26 No. 2 (2017): June Vol. 26 No. 1 (2017): March Vol. 25 No. 4 (2016): December Vol. 25 No. 3 (2016): September Vol. 25 No. 2 (2016): June Vol. 25 No. 1 (2016): March Vol. 24 No. 4 (2015): December Vol. 24 No. 3 (2015): September Vol. 24 No. 2 (2015): June Vol. 24 No. 1 (2015): March Vol. 23 No. 4 (2014): November Vol. 23 No. 3 (2014): August Vol. 23 No. 2 (2014): May Vol. 23 No. 1 (2014): February Vol. 22 No. 4 (2013): November Vol. 22 No. 3 (2013): August Vol. 22 No. 2 (2013): May Vol. 22 No. 1 (2013): February Vol. 21 No. 4 (2012): November Vol. 21 No. 3 (2012): August Vol. 21 No. 2 (2012): May Vol. 21 No. 1 (2012): February Vol. 20 No. 4 (2011): November Vol. 20 No. 3 (2011): August Vol. 20 No. 2 (2011): May Vol. 20 No. 1 (2011): February Vol. 19 No. 4 (2010): November Vol. 19 No. 3 (2010): August Vol. 19 No. 2 (2010): May Vol. 19 No. 1 (2010): February Vol. 18 No. 4 (2009): October-December Vol. 18 No. 3 (2009): July-September Vol. 18 No. 2 (2009): April-June Vol. 18 No. 1 (2009): January-March Vol. 17 No. 4 (2008): October-December Vol. 17 No. 3 (2008): July-September Vol. 17 No. 2 (2008): April-June Vol. 17 No. 1 (2008): January-March Vol. 16 No. 4 (2007): October-December Vol. 16 No. 3 (2007): July-September Vol. 16 No. 2 (2007): April-June Vol. 16 No. 1 (2007): January-March Vol. 15 No. 4 (2006): October-December Vol. 15 No. 3 (2006): July-September Vol. 15 No. 2 (2006): April-June Vol. 15 No. 1 (2006): January-March Vol. 14 No. 4 (2005): October-December Vol. 14 No. 3 (2005): July-September Vol. 14 No. 2 (2005): April-June Vol. 14 No. 1 (2005): January-March Vol. 13 No. 4 (2004): October-December Vol. 13 No. 3 (2004): July-September Vol. 13 No. 2 (2004): April-June Vol. 13 No. 1 (2004): January-March Vol. 12 No. 4 (2003): October-December Vol. 12 No. 3 (2003): July-September Vol. 12 No. 2 (2003): April-June Vol. 12 No. 1 (2003): January-March Vol. 11 No. 4 (2002): October-December Vol. 11 No. 3 (2002): July-September Vol. 11 No. 2 (2002): April-June Vol. 11 No. 1 (2002): January-March Vol. 10 No. 4 (2001): October-December Vol. 10 No. 3 (2001): July-September Vol. 10 No. 2 (2001): April-June Vol. 10 No. 1 (2001): January-March Vol. 9 No. 4 (2000): October-December Vol. 9 No. 3 (2000): July-September Vol. 9 No. 2 (2000): April-June (Special Issue: Skin Cancer) Vol. 9 No. 1 (2000): January-March Vol. 8 No. 4 (1999): October-December Vol. 8 No. 3 (1999): July-September Vol. 8 No. 2 (1999): April-June (Special Issue: Breast Cancer) Vol. 8 No. 1 (1999): January-March (Special Issue: Implant Contraceptive) Vol. 7 No. 4 (1998): October-December Vol. 7 No. 3 (1998): July-September Vol. 7 No. 2 (1998): April-June Vol. 7 (1998): Supplement 1 Vol. 7 No. 1 (1998): January-March Vol. 6 No. 4 (1997): October-December Vol. 6 No. 3 (1997): July-September Vol. 6 No. 2 (1997): April-June Vol. 6 No. 1 (1997): January-March Vol. 5 No. 4 (1996): October-December Vol. 5 No. 3 (1996): July-September Vol. 5 No. 2 (1996): April-June Vol. 5 No. 1 (1996): January-March Vol. 4 No. 4 (1995): October-December Vol. 4 No. 3 (1995): July-September Vol. 4 No. 2 (1995): April-June Vol. 4 No. 1 (1995): January-March Vol. 3 No. 4 (1994): October-December Vol. 3 No. 3 (1994): July-September Vol. 3 No. 2 (1994): April-June Vol. 3 No. 1 (1994): January-March Vol. 2 No. 1 (1993): January-March Vol. 1 No. 3/4 (1992): July-December Vol. 1 No. 2 (1992): April-June Vol. 1 No. 1 (1992): January-March More Issue