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INDONESIA
Medical Journal of Indonesia
Published by Universitas Indonesia
ISSN : 08531773     EISSN : 22528083     DOI : 10.13181
Core Subject : Health,
Medicine & Pharmacology
This quarterly medical journal is an official scientific journal of the Faculty of Medicine Universitas Indonesia in collaboration with German-Indonesian Medical Association (DIGM) Indexed in: IMSEAR; CAB Abstracts; Global Health; HINARI; DOAJ; DRJI; Google Scholar; JournalTOCs; Ulrichsweb Global Serial Directory; WorldCat; New Jour; Electronic Journals Library; ISJD Accredited (2013-2018) by DIKTI Kemendikbud Republik Indonesia (No:58/DIKTI/Kep/2013)
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Articles 10 Documents
 1 
Search results for , issue "Vol. 12 No. 3 (2003): July-September" : 10 Documents clear
Acute eye irritation study of a mixture of glyphosate isopropylamine salt and 2,4 D-isopropylamine
Medical Journal of Indonesia Vol. 12 No. 3 (2003): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i3.102

Abstract

This is an acute irritation study of the eye of a mixture of herbicides containing 240 g/l of glyphosate isopropylamine and 2,4 D-isopropylamine in the rabbits. This study was conducted according the methods as dercribed by the United States Environmental Protection Agency (EPA). Our results show that the combination of the herbicides causes mild conjunctivitis, mild chemosis, eye discharge and corneal injury. The ocular alteration, however, was reversible in nature. (Med J Indones 2003; 12: 135-41)
Asthma prevalence among high school students in East Jakarta, 2001, based on ISAAC questionnaire
Medical Journal of Indonesia Vol. 12 No. 3 (2003): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i3.103

Abstract

The aim of this study was to assess asthma prevalence in children between 13-14 years of age in East Jakarta. This study is a cross sectional study which surveyed 2234 high school students between the ages of 13 and 14 years in East Jakarta in 2001 using the ISAAC questionnaire. Bronchial challenge test was applied by using methacholine substance to 186 students. Reports based on the ISAAC questionnaire indicate that 7.2% of teenage have had the wheezing experience, 4.1% have wheezing within the last 12 months, 1.8% have ever suffered severe asthma attack within the last 12 months, 3.3% have suffered wheezing after exercise, and 6.3% have got night cough while they were not suffering from cold. Prevalence of atopy diseases such as rhinitis and eczema were 14.2% and 3.9%, meanwhile rhinitis and eczema prevalence within the last 12 months according to this study were 10.6% and 2.9% respectively. Statistically, there is a significant correlation between wheezing symptom and atopy (p < 0.05). From indepth questionnaire, a significant value of kappa 0.84 related with wheezing within the last 12 months was found. Bronchial challenge test results indicate that sensitivity was 90%, specificity 83.58%, positive predictive value 68.12% and negative predictive value was 95.73%. Asthma prevalence in East Jakarta at 2001 based on ISAAC questionnaire was 8.9%, and cumulative prevalence 11.5%. The ISAAC questionnaire can be used to study asthma prevalence in children at multicenter in Indonesia. (Med J Indones 2003; 12: 178-86)
Periosteal osteosarcoma: A case report
Medical Journal of Indonesia Vol. 12 No. 3 (2003): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i3.104

Abstract

Periosteal osteosarcoma is a rare type of malignant bone neoplasm, with predominantly cartilaginous component and arising on the bone surface. Reports of the case in the literature were rare. Last case was reported by Mayo Clinic in 1999. We report a case of periosteal osteosarcoma in a 17-year-old male, who was treated surgically with a limb salvage procedure, neoadjuvant and adjuvant chemotherapy were also given to the patient. There was no local recurrence and lung metastases up to 14 months after surgery. (Med J Indones 2003; 12: 166-70)
An analysis on the delay of cervical cancer patients in seeking medical check up in Dr. Cipto Mangunkusumo National Central General Hospital Jakarta
Medical Journal of Indonesia Vol. 12 No. 3 (2003): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i3.105

Abstract

In Indonesia, most cervical cancer patients seek medical help after the cancer has reached advanced stage (62 %). This has caused cervical cancer to contribute to 66 % of gynecological deaths. The objective of this study is to find out factors related to the delay of cervical cancer patients in seeking for medical help. This research employs quantitative and qualitative methods. Samples were obtained from all of the new cervical cancer patients who came for the first time between 2000 to 2001 and returned to the Dr. Cipto Mangunkusumo National Central General Hospital Jakarta from August until October 2001. It is concluded that variables significantly correlated with the delay for medical check up are knowledge, attitude, the availability of Pap smear service and husband support. The availability of Pap smear plays as dominant variabel. (Med J Indones 2003; 12: 162-5)
Surgeon factor on laser in situ keratomileusis in low and moderate myopia
Medical Journal of Indonesia Vol. 12 No. 3 (2003): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i3.106

Abstract

The purpose of this study was to evaluate the effectiveness and predictability of laser in situ keratomileusis (LASIK) procedure performed by three surgeons in low and moderate myopia. One hundred twenty nine eyes from 68 patients underwent LASIK procedure, performed by three different surgeons (X, Y, Z) using the same procedure and same instruments were reviewed. These patients are divided into two groups, group A (below - 6.00 diopters) and group B (between - 6.00 and - 10.00 diopters). Patients were observed on day 1, day 7, 1st month and 3rd month. Results: The evaluation of effectiveness and predictability is based upon uncorrected visual acuity (UCVA) and spherical equivalent refraction, respectively. The variation dispersion between attempted correction and achieved correction is measured using coefficient of determination (R2). The statistical analysis shows indifferent results for the three surgeons. The conclusion was that the effectiveness and predictability of LASIK procedure performed by the three surgeons in both groups are indifferent. Hence, this study suggests that the surgeon factor does not affect the result of LASIK procedure. (Med J Indones 2003; 12: 148-54)
The efficacy of specific patterns of movements and brain exercises on the cognitive performance of healthy senior citizen in Jakarta
Medical Journal of Indonesia Vol. 12 No. 3 (2003): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i3.107

Abstract

The objective of this study was to determine the efficacy of brain movement and exercise in healthy senior subjects. Brain movement and exercise or Gerak dan Latih Otak (GLO) which comprised of muscles stretching, breathing exercise, and crossing the body's midline of the eyes, head and extremities were performed two times weekly for two months by 70 normal healthy senior subjects. A pre- and posttest on 5 cognitive performance, consisted of visual scanning and tracking (VST), delayed recall (DR), verbal fluency (VF), digits backward (DB), and trail making test-B (TMT-B). The age range of the subjects was 48 to 70 years and duration of education ranged from 6 to 18 years or more. The results of the statistical analyses showed that all the subjects showed high significant increase performance on the five cognitive domains. Women performed significantly in all the tests, while in men the significant increase was on VST, DR, and TMT-B. No different significant increase cognitive performance could be obtained between the two age groups (below 60 years and 60 years upward) and level of education, except for the high education group. It is suggested that further studies with larger scale subjects and same methodology should be performed in several places in Indonesia. (Med J Indones 2003; 12: 155-61)
Vulvovaginal candidosis caused by Candida non-albicans, proportion and clinical characteristics in the Dr. Cipto Mangunkusumo National General Hospital, Jakarta
Medical Journal of Indonesia Vol. 12 No. 3 (2003): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i3.108

Abstract

The prevalence of vulvovaginal candidosis (VVC) caused by C. non-albicans tends to increase, recently. The aim of this study was to obtain data about proportion and clinical characteristic of C. non-albicans VVC at dr. Cipto Mangunkusumo General Hospital, Jakarta. This is a cross-sectional study on all female patients with symptoms of VVC visiting Obstetri-gynaecology and Dermatovenereology outpatient clinics at dr. Cipto Mangunkusumo General Hospital, Jakarta. All subjects had positive Gram stain, showed Candida spp. on culture with CHROMagar Candida, and had no other specific genital infections. Sixty nine subjects aged 26–44 years old (averaged 29 years old) were included in this study. Candida non-albicans was found in 30.4% subject, and consisted of: C. glabrata (61.9%), C. tropicalis (28.6%) and C. parapsilosis (9.5%). We found that C. non-albicans VVC infections are more common in women above 45 years old, using non-hormonal contraceptives, whose sexual partner has erythema and pruritus in glands penis, and having the disease for more than 1 year. No differences in clinical symptoms were noted between C. albicans and C. non-albicans infection. We concluded from this study that the proportion of C. non-albicans infections at dr. Cipto Mangunkusumo General Hospital, Jakarta, with C. glabrata represents the most prevalent species. No characteristic clinical symptoms were found from the subjects with C. non-albicans VVC when compared with those infected by C. albicans. (Med J Indones 2003; 12: 142-7)
Air movement, gender and risk of sick building headache among employees in a Jakarta office
Medical Journal of Indonesia Vol. 12 No. 3 (2003): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i3.109

Abstract

Even though office buildings are usually equipped with ventilation system or air conditioning to create a comfortable working environment, yet there is still found a number of sick building syndrome (SBS) symptoms. One of the symptoms of SBS is SBS headache. Therefore, it is crucial to identify risk factors related to SBS headache. Cases were subjects who have suffered SBS headache, and controls were subjects who did not suffered headache for the last one month. Cases and controls were selected through a survey on all of employees in the said office during the period of May to August 2002. Total respondents were 240 employees including 36 people suffered SBS headache (15%). Compared to the normal air movement, faster air movement decreased the risk of SBS headache by 57% [adjusted odds ratio (OR) = 0.43; 95% confidence intervals (CI): 0.19-0.95]. Female employees, compared to the males ones, had a higher risk of getting SBS headache by almost three times (adjusted OR = 2.96: 95% CI: 1.29-6.75). Employees who had breakfast irregularly, had a lower risk to SBS headache than those who have breakfast regularly (adjusted OR=0.31; 95% CI: 0.09-0.84). Temperature, humidity and smoking habits were not noted correlated to SBS headache. Female workers had greater risk of suffering SBS headache. In addition slower air movement increased the risk of SBS headache. Therefore, it is recommended to improve the progress of air in order to reduce the risk of SBS headache, especially for female workplace. (Med J Indones 2003; 12: 171-7)
The expression of follicle-stimulating hormone receptor in ovary and testis
Medical Journal of Indonesia Vol. 12 No. 3 (2003): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i3.110

Abstract

Follicle-stimulating hormone receptor (FSHR) is exclusively expressed in granulose cells of the ovary and Sertoli cells of the testis.The highly cell-specific of gene expression revealed that transcriptional events unique to these two cell types areresponsible for activation of the FSHR gene. Even though its mechanisms are still unclear, several progress regarding the mechanism that control its basal transcription and regulation has been made. It has been identified several important elements that responsible for the transcription of the TATA-less FSHR gene such as: E box element (CACG(A)TG, –124/–119), an inverted GATA (TATC, –88/–85), E2F (TTTCGCG, –45/–39), and regulator element-3 (–197/–171). The functional studies shown that mutations through these regulatory elements significantly decrease the promoter function with greatest impact detected when mutation was done in E-box element. The site-specific CpG methylation within the core promoter seems play an important role in the regulation of rat and mouse FSHR gene expression. (Med J Indones 2003; 12: 187-93)
The use of 17β Estradiol gel and progestogen tablet for hormone replacement therapy (HRT) in menopause
Medical Journal of Indonesia Vol. 12 No. 3 (2003): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v12i3.111

Abstract

The treatment and prevention of disease in menopausal women due to deficiency of estrogen hormone are done through the administration of estrogen hormone, known as hormone replacement therapy (HRT). The administration of HRT is commonly done through the administration of tablets. However, the administration of tablet will result in metabolism in the colon and liver. Tablets are usually used on a daily basis such that it may lead to boredom and results in gastrointestinal disorder. The administration of gel, on the other hand, is done by applying the gel to the body and therefore metabolism in the colon and liver can be prevented. In women with uterus, estrogen must be combined with progestogen. The type of progestogen recommended is the one with natural derivative and which possesses antimineralocorticoid properties, such that fluid retention can be avoided. One of the types of progestogen which does not result in fluid retention is nomogestrol acetate. Nomogestrol acetate will also inhibit 17β hydrosisteroiddehydrogency enzyme type 1, such that estradiol (E2) is prevented from being transformed into estron (E1). As a result, E2 level in the breast tissue is kept at minimum, thereby reducing the risk of breast cancer. (Med J Indones 2003; 12: 194-8) Keywords: , ,,,

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