cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Tsania Faza
Contact Email
-
Phone
08111400115
Journal Mail Official
mji@ui.ac.id
Editorial Address
Education Tower 6th floor, IMERI building, Faculty of Medicine Universitas Indonesia, Jalan Salemba Raya 6, Jakarta, 10430, Indonesia
Location
Kota depok,
Jawa barat
INDONESIA
Medical Journal of Indonesia
Published by Universitas Indonesia
ISSN : 08531773     EISSN : 22528083     DOI : 10.13181
Core Subject : Health,
Medicine & Pharmacology
This quarterly medical journal is an official scientific journal of the Faculty of Medicine Universitas Indonesia in collaboration with German-Indonesian Medical Association (DIGM) Indexed in: IMSEAR; CAB Abstracts; Global Health; HINARI; DOAJ; DRJI; Google Scholar; JournalTOCs; Ulrichsweb Global Serial Directory; WorldCat; New Jour; Electronic Journals Library; ISJD Accredited (2013-2018) by DIKTI Kemendikbud Republik Indonesia (No:58/DIKTI/Kep/2013)
Arjuna Subject : -
Articles 11 Documents
 1   2 
Search results for , issue "Vol. 14 No. 1 (2005): January-March" : 11 Documents clear
Does VEGF concentration in pre-eclamptic serum induce sVCAM-1 production in endothelial cell culture?
Medical Journal of Indonesia Vol. 14 No. 1 (2005): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i1.163

Abstract

Serum concentrations of VEGF (Vascular Endothelial Growth Factor) are elevated in preeclampsia. In addition to inducing mitosis and increase permeability of endothelial cells, VEGF was reported to activate endothelial cells to produce cell adhesion molecules. Cell adhesion molecules play an important role in the inflammation process by inducing adherence of leukocytes in blood stream to the endothelial cells. The aim of this study is to investigate the effect of VEGF in serum from preeclamptic patients on sVCAM-1 (soluble vascular adhesion molecules-1) production in endothelial cell culture. Twelve sera from women with preeclampsia and 11 from women with normal pregnancy (controls) in 20% concentration were added to human umbilical vein endothelial cell culture (HUVEC) and incubated for 24 hours. All subjects have agreed to participate in this study and signed the informed consent form. sVCAM-1 concentration in the supernatant was measured by ELISA. VEGF concentration tends to be higher in preeclamptic serum than control, but the difference is not stastitically significant. The production of sVCAM-1 by endothelial cells exposed to preeclamptic serum was significantly higher than the production by endothelial cells exposed to serum from control (p<0.05). No correlation was found between the difference in VEGF concentrations in preeclamptic and control sera, and sVCAM-1 production by endothelial cell culture. (Med J Indones 2005; 14: 3-6) Keywords: endothelial cell, preeclampsia, VCAM, VEGF
Assessment of clinical and laboratory parameters that reflect inflammatory response and organ function in sepsis
Medical Journal of Indonesia Vol. 14 No. 1 (2005): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i1.164

Abstract

Sepsis is a spectrum of clinical conditions caused by the host immune response to infection or other inflammatory stimuli characterized by systemic inflammation. Clinical response to sepsis could be varies according to compensate or decompensate state, inflammatory process and host condition. Aims of this study is to assess the role of some parameters (clinical and biochemical, hematology, arterial blood gas analysis and coagulation) in supporting the diagnosis of sepsis. A cross-sectional study was performed in the Internal Medicine Inpatient Unit of Dr. Cipto Mangunkusumo National General Hospital, Jakarta, from February to July 2002. Forty-two patients who fulfilled the criteria of sepsis, severe sepsis, and septic shock were enrolled in this study. Clinical details and blood specimens for hematological, biochemical, arterial blood gas analysis and coagulation were collected. There were 42 subjects who participated in the study, aged from 19 to 78 years old. Eleven subjects fulfilled the criteria for early sepsis, 20 severe sepsis and 11 septic shock. Clinical examination showed that the Glasgow coma scale (GCS) was significantly reduced in severe sepsis and septic shock. Heart rate, respiration rate and body temperature were increased in all groups. Hemoglobin levels mostly below 10 g/dl and hematocrite levels below 30 %. The leucocyte counts were increased in more than 80%, mostly above 15.000/mm3. The platelet count were low (below 50.000/mm3) especially in septic shock. The serum creatinine were significantly increased (>2 mg/dl) in severe sepsis and septic shock. Albumin was decreased, lactate dehydrogenase/LDH and procalcitonin were increased. The arterial blood gas analysis showed that: pH and HCO3 were decreased especially in septic shock; the PO2 was lower in severe sepsis and septic shock; and PCO2 was below 32 mmHg in all groups. Coagulation examinations showed that fibrinogen was significantly decreased in septic shock; PT and APTT were prolong in severe sepsis and septic shock more than 18.8 and 48 seconds respectively. The d-dimer was also increased mostly in all groups. In conclusions that clinical examinations include level of consciousness, heart rate, mean arterial pressure, temperature and respiration rate and additional laboratory examinations include hamatological, biochemical, blood gas analysis and coagulation examinations can be used as parameters in diagnosis of sepsis. Some parameters include level of consciousness (Glasgow coma scale), serum creatinine, hemoglobin, platelet count and fibrinogen can differ sepsis according to severity. (Med J Indones 2005; 14: 26-32)Keywords: Clinical response, SIRS, sepsis
Difficult factors in Management of Impacted Dental Prosthesis in Esophagus
Medical Journal of Indonesia Vol. 14 No. 1 (2005): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i1.165

Abstract

A dental prosthesis which ingested and impacted in esophagus, is an emergency case and life threatening, so require immediateesophagoscopy intervention for removing.The objective of this study is to assess some factors can caused dtfficulties in diagnosing and treating the ingested and impacted dental prosthesis in the esophagus and their complications.This retrospective study analyzed patient’s chart whose underwent esophagoscopy for removing the impacted dental prosthesis in Dr. CiptoMangunkusumo General Hospital, Jakarta, Indonesia during a period between January 1997 and December 2003. Neck-chest X-ray and esophagoscopy were performed in all patients to identify the existence of the dental prosthesis as a diagnostic and treatment procedure. The length of time for removing the dental prosthesis was recorded and stated as a less difficult esophagoscopy when it takes time less than 60 minutes and as a difficult esophagoscopy takes 60 minutes or longer. Some risk difficultiesfactors were statistically analyzed.There were 53 patients of ingested dental prosthesis in esophagus. Only 51 cases were analyzed According to the length of time for removingthe dental prosthesis by esophagoscopy, 22 patients were recorded as less difficult cases and 29 patients as difficultcases. Two cases among the cases needed cervicotomy after unsuccessful esophagoscopy removal.The difficultiesto diagnose an impacted dental prosthesis in the esophagus caused by unreliable clinical history, unclear signs and symptoms, unableto be detected by X-ray and was not found during esophagoscopy. The difficulties in treating due to mucosal laceration, edema, bleeding, failure of the first extraction and conformity with the size and shape, the wire outside the dental prosthesis and thelength of time stayed in the esophagus. (Med J Indones 2005; 14: 33-6) Keywords: ingested dental prosthesis, radioluscent foreign body, length of time of esophagoscopy
First-line chemotherapy of advanced or metastatic breast cancer (MBC) with docetaxel and doxorubicin in Indonesia: results from A phase II trial
Medical Journal of Indonesia Vol. 14 No. 1 (2005): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i1.166

Abstract

Doxorubicin and docetaxel as a single agent are known as active cytotoxic agents for the treatment of metastatic breast cancer (MBC). Their combination has also shown to be highly active as a second-line chemotherapy of MBC. This study was design to evaluate the efficacy and safety of docetaxel-doxorubicin combination as first line chemotherapy of MBC patients in Indonesia. Twenty-six female patients between 31-65 years old with advanced or MBC was enrolled. No prior taxane or cumulative doxorubicin of 250 mg/m2 was allowed and patients should not have a heart disease. Treatment consisted of doxorubicin 50 mg/m2 as intravenous (IV) bolus followed one hour later by docetaxel 60 mg/m2 by IV infusion over 1 hour every 3 weeks for 6 cycles. Premedication with oral corticosteroid was administered a day prior to chemotherapy until the second day of each cycle. Left ventricular ejection fraction was recorded at baseline and after the 6th cycle. At the end of study, a total of 156 cycles of chemotherapy have been delivered. Five and 11 patients had a complete response (CR) and partial response (PR), respectively, which accounted for a 61.54% best overall response. Three patients with extensive liver metastases showed complete disappearance after 6 cycles. Most frequent grade 3-4 toxicities were leukopenia (80.77%) and febrile neutropenia (5.77%). Leukopenia was usually short in duration, occurred mainly during the first and second cycle and did not require dose reduction. No patient developed heart failure. There was one death due to progressive disease after 6 cycles. Combination of doxorubicin 50 mg/m2 and docetaxel 60 mg/m2 was sufficiently active as first-line chemotherapy of MBC, especially in patients with liver metastases, with a manageable toxicity profile. (Med J Indones 2005; 14: 20-5) Keywords: docetaxel, doxorubicin, advanced or metastatic breast cancer, phase II trial, anthracycline and taxane combination
Onset response of bupivacaine 0.5% which has been added with sodium bicarbonate on epidural block
Medical Journal of Indonesia Vol. 14 No. 1 (2005): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i1.167

Abstract

There are many advantages in using epidural anesthesia technique.However, there are also some constraints, such as the relatively long onset, particularly in the case of bupivacaine.Whereas the need of a rapid onset ofanesthesia technique for emergency cares is increasinglately. The objectiveof this studywas to find a method to hasten theonset of bupivacaine. This is a cross sectionalrandomized double blind controlled clinical trial performed on 40 patients who would undergo lower abdomen and extremity surgerywith epidural block.We evaluated the onset of action of bupivacaine which hasbeen added with sodium bicarbonate. Consecutive sampling method was appliedto get the sample. Thecriteria of sample are ASA I –II patient, agedof 20-60 years old, 50-60 kg of weight, 150-170 cm of height. Patients wereallocated randomly into two groups. The treatment group would get epidural block using mixtureof 20 cc of bupivacaine 0,5% + 0.5 cc of sodium bicarbonate 1.4 %, whereas the control group received20 cc bupivacaine 0.5 % + 0.5 cc aqua bides.Time to reach sensoric blockat the level of thoracal 10 dermatomeusing the pinprick methodand time to reach motoric blockade usingthe bromage scalewas recorded. The result of this study showed a significant shortening of theonset of sensory blockade (p<0.05) in the treatment group (10.2+1.4 minutes) compared with the control group (19.5+1.3 minutes). The onset of motor blockade had also a significant shortening (p<0.05) in the treatment group(13.3+1.6 minutes) compared with the control group (23.0+1.2 minutes). It was concluded that the additionof sodium bicarbonate can hasten the onset of bupivacaine on epidural block. (Med J Indones 2005; 14: 7-10) Keywords : onset response, bupivacaine 0.5%, sodium bicarbonate, epidural block
Safety and tolerability of moxifloxacin in the treatment of respiratory tract infections: a post-marketing surveillance conducted in Indonesia
Medical Journal of Indonesia Vol. 14 No. 1 (2005): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i1.168

Abstract

Moxifloxacin 400 mg tablet has been marketed in Indonesia for several indications, i.e. acute exacerbation of chronic bronchitis (AECB), community-acquired pneumonia (CAP), and acute bacterial sinusitis (ABS). To assess the safety and tolerability of moxifloxacin, a post-marketing surveillance study was conducted in the year 2001 involving 589 physicians. Clinical efficacy was also evaluated, both by physicians and patients, using a 6-symptom total score, which was scaled 0-12. A total of 1715 patients with acute sinusitis, CAP, AECB, and other infections were treated with oral moxifloxacin 400 mg once daily. There were 151 (8.8%) patients with adverse events (AEs) and 5 (0.29%) patients with serious adverse events (SAEs) that were considered related to moxifloxacin treatment. The most common adverse reactions were nausea (4.96%), dizziness (1.52 %), vomiting (0.64%), headache (0.47%), andweakness (0.47%). Twenty three (1.34%) patients discontinued treatment due to adverse events. Tolerance to treatment was rated very good and good by 647 (37.7%) and 919 (53.6%) of patients, respectively. Based on physicians’ clinical assessment, 57.7% of patients were cured and 39.9% were improved at the end of treatment. Mean total symptom score, as assessed by the patients, decreased from 6.43 on day-1 to 2.76 on day-3. Totally, 95.3% of patients felt better after receiving moxifloxacin and 97.6% of patients had good impression on moxifloxacin treatment. In conclusion, treatment of respiratory tract infections, mainly AECB, CAP and ABS, with moxifloxacin 400 mg once daily in this post-marketing surveillance was shown to be safe and well tolerated. Moxifloxacin was also shown to be highly effective in the treatment of these infections with rapid improvement of symptoms. (Med J Indones 2005; 14: 11-19) Keywords : post-marketing survtillance, PMS, moxifloxacin, respiratory tract infections
The effect of high protein enteral nutrition on protein status in acute stroke patients
Medical Journal of Indonesia Vol. 14 No. 1 (2005): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i1.169

Abstract

The objective of this study was to determine the effect of high protein enteral nutrition on protein status in acute stroke patients. The subjects were divided into two groups using block randomisation, i.e. the intervention group that received high protein enteral nutrition (HPEN), and the control group that received enteral hospital diet. Thirty six out of 60 acute stroke patients had completed 7 days of follow-up. The results showed that HPEN have increased prealbumin level, decreased urinary creatinine excretion, and decreased the decline of albumin serum compared to the control group. (Med J Indones 2005; 14: 37-43) Keywords: albumin, prealbumin, urinary urea nitrogen, urinary creatinine, nitrogen balance
Antibiotic prescription practices in six primary health centers in South Sumatra
Medical Journal of Indonesia Vol. 14 No. 1 (2005): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i1.170

Abstract

Drug utilization study, especially antibiotic usage in therapy of mild acute upper respiratory infections and acute diarrheas has been conducted in six Primary Health Center (PHC) in urban, suburban and rural area in the Province of South Sumatra. We conducted systematic random sampling during which 15% of patients in each PHC were taken. We collected information about drug utilization from medical record of out patient in each PHC for three months period (January to March 1997). We recorded the characteristics of patients, the diagnosis, the number and type of drug (including injection) used. The number of cases studied was 1781, with the average number of drug per prescription being 2.7; the percentage of cases receiving an injection was 43%, and the percentage of cases receiving antibiotic was 48%. Sixty-four percent of 1277 acute respiratory tract infections (common cold), and 79% of 140 cases of acute diarrhea received antibiotic. This study showed that there is overuse or inappropriate use of drugs, especially antibiotic for acute nonspecific diarrhea and mild acute respiratory tract infections. (Med J Indones 2005; 14: 44-9) Keywords: drug utilization study, antibiotic use, acute upper respiratory infection, acute diarrhea
Non-Ulcer dyspepsia relation with environmental factors - A study in Sub Himalayas, India
Medical Journal of Indonesia Vol. 14 No. 1 (2005): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i1.171

Abstract

Non ulcer dyspepsia is a common gastrointestinal problem, the etiopathogenesis of which is not well established. This study was planned to see the effect of environmental factors like smoking, tea, alcohol, and NSAIDs consumption with non-ulcer dyspepsia. This study was conducted in the department of Gastroenterology, Medicine and Radiology of I.G. Medical College, Shimla, India. Three hundred patients of non-ulcer dyspepsia were included in the study. Each case was matched with community control of same age and sex. A detailed history of smoking, tea, alcohol, and NSAIDs consumption was taken from the patients and controls. Consumption of tea as an environmental factor was found to be statistically significant in non-ulcer dyspepsia patients as compared to controls using multivariate regression. In the present study, environmental factors like smoking, alcohol, NSAIDs consumption did not show positive co-relation with non-ulcer dyspepsia. (Med J Indones 2005; 14: 50-4) Keywords: smoking, alcohol, tea, Non-steroidal anti-inflammatory drugs (NSAIDs)
Current status of glucosamine and chondroitin therapy in osteoarthritis
Medical Journal of Indonesia Vol. 14 No. 1 (2005): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v14i1.172

Abstract

Osteoarthritis (OA) is the most common form of arthritis. Radiographic and or pathologic changes of OA are present in most people older than 65 years old. The management of OA is divided into medical / non surgical and surgical treatment. The medical treatment consisted of pharmacologic and non pharmacologic treatment. The pharmacologic treatment of OA is still problematic for many patients, either due to a lack of efficacy or due to the toxicity of the drugs used in the treatment of OA, so that many OA patients seek for alternative medication. Glucosamine and chondroitin are the most commonly used alternative agents for the treatment in OA. Many studies had been conducted to evaluate the efficacy of glucosamine and chondroitin in the treatment of OA. So far the result is controversial. The purpose of this article is to highlight the current status of the use of glucosamine and chondroitin in OA treatment. (Med J Indones 2005; 14: 55-8) Keywords: Osteoarthritis, Glucosamine, Chondroitin

Page 1 of 2 | Total Record : 11

 1   2 

Filter by Year

2005 2005


Reset
Filter By Issues
All Issue Online First Vol. 34 No. 4 (2025): December Vol. 34 No. 3 (2025): September Vol. 34 No. 2 (2025): June Vol. 34 No. 1 (2025): March Vol. 33 No. 4 (2024): December Vol. 33 No. 3 (2024): September Vol. 33 No. 2 (2024): June Vol. 33 No. 1 (2024): March Vol. 32 No. 4 (2023): December Vol. 32 No. 3 (2023): September Vol. 32 No. 2 (2023): June Vol. 32 No. 1 (2023): March Vol. 31 No. 4 (2022): December Vol. 31 No. 3 (2022): September Vol. 31 No. 2 (2022): June Vol. 31 No. 1 (2022): March Vol. 30 No. 4 (2021): December Vol. 30 No. 3 (2021): September Vol. 30 No. 2 (2021): June Vol. 30 No. 1 (2021): March Vol. 29 No. 4 (2020): December Vol. 29 No. 3 (2020): September Vol. 29 No. 2 (2020): June Vol. 29 No. 1 (2020): March Vol. 28 No. 4 (2019): December Vol. 28 No. 3 (2019): September Vol. 28 No. 2 (2019): June Vol. 28 No. 1 (2019): March Vol. 27 No. 4 (2018): December Vol. 27 No. 3 (2018): September Vol. 27 No. 2 (2018): June Vol. 27 No. 1 (2018): March Vol. 26 No. 4 (2017): December Vol. 26 No. 3 (2017): September Vol. 26 No. 2 (2017): June Vol. 26 No. 1 (2017): March Vol. 25 No. 4 (2016): December Vol. 25 No. 3 (2016): September Vol. 25 No. 2 (2016): June Vol. 25 No. 1 (2016): March Vol. 24 No. 4 (2015): December Vol. 24 No. 3 (2015): September Vol. 24 No. 2 (2015): June Vol. 24 No. 1 (2015): March Vol. 23 No. 4 (2014): November Vol. 23 No. 3 (2014): August Vol. 23 No. 2 (2014): May Vol. 23 No. 1 (2014): February Vol. 22 No. 4 (2013): November Vol. 22 No. 3 (2013): August Vol. 22 No. 2 (2013): May Vol. 22 No. 1 (2013): February Vol. 21 No. 4 (2012): November Vol. 21 No. 3 (2012): August Vol. 21 No. 2 (2012): May Vol. 21 No. 1 (2012): February Vol. 20 No. 4 (2011): November Vol. 20 No. 3 (2011): August Vol. 20 No. 2 (2011): May Vol. 20 No. 1 (2011): February Vol. 19 No. 4 (2010): November Vol. 19 No. 3 (2010): August Vol. 19 No. 2 (2010): May Vol. 19 No. 1 (2010): February Vol. 18 No. 4 (2009): October-December Vol. 18 No. 3 (2009): July-September Vol. 18 No. 2 (2009): April-June Vol. 18 No. 1 (2009): January-March Vol. 17 No. 4 (2008): October-December Vol. 17 No. 3 (2008): July-September Vol. 17 No. 2 (2008): April-June Vol. 17 No. 1 (2008): January-March Vol. 16 No. 4 (2007): October-December Vol. 16 No. 3 (2007): July-September Vol. 16 No. 2 (2007): April-June Vol. 16 No. 1 (2007): January-March Vol. 15 No. 4 (2006): October-December Vol. 15 No. 3 (2006): July-September Vol. 15 No. 2 (2006): April-June Vol. 15 No. 1 (2006): January-March Vol. 14 No. 4 (2005): October-December Vol. 14 No. 3 (2005): July-September Vol. 14 No. 2 (2005): April-June Vol. 14 No. 1 (2005): January-March Vol. 13 No. 4 (2004): October-December Vol. 13 No. 3 (2004): July-September Vol. 13 No. 2 (2004): April-June Vol. 13 No. 1 (2004): January-March Vol. 12 No. 4 (2003): October-December Vol. 12 No. 3 (2003): July-September Vol. 12 No. 2 (2003): April-June Vol. 12 No. 1 (2003): January-March Vol. 11 No. 4 (2002): October-December Vol. 11 No. 3 (2002): July-September Vol. 11 No. 2 (2002): April-June Vol. 11 No. 1 (2002): January-March Vol. 10 No. 4 (2001): October-December Vol. 10 No. 3 (2001): July-September Vol. 10 No. 2 (2001): April-June Vol. 10 No. 1 (2001): January-March Vol. 9 No. 4 (2000): October-December Vol. 9 No. 3 (2000): July-September Vol. 9 No. 2 (2000): April-June (Special Issue: Skin Cancer) Vol. 9 No. 1 (2000): January-March Vol. 8 No. 4 (1999): October-December Vol. 8 No. 3 (1999): July-September Vol. 8 No. 2 (1999): April-June (Special Issue: Breast Cancer) Vol. 8 No. 1 (1999): January-March (Special Issue: Implant Contraceptive) Vol. 7 No. 4 (1998): October-December Vol. 7 No. 3 (1998): July-September Vol. 7 No. 2 (1998): April-June Vol. 7 (1998): Supplement 1 Vol. 7 No. 1 (1998): January-March Vol. 6 No. 4 (1997): October-December Vol. 6 No. 3 (1997): July-September Vol. 6 No. 2 (1997): April-June Vol. 6 No. 1 (1997): January-March Vol. 5 No. 4 (1996): October-December Vol. 5 No. 3 (1996): July-September Vol. 5 No. 2 (1996): April-June Vol. 5 No. 1 (1996): January-March Vol. 4 No. 4 (1995): October-December Vol. 4 No. 3 (1995): July-September Vol. 4 No. 2 (1995): April-June Vol. 4 No. 1 (1995): January-March Vol. 3 No. 4 (1994): October-December Vol. 3 No. 3 (1994): July-September Vol. 3 No. 2 (1994): April-June Vol. 3 No. 1 (1994): January-March Vol. 2 No. 1 (1993): January-March Vol. 1 No. 3/4 (1992): July-December Vol. 1 No. 2 (1992): April-June Vol. 1 No. 1 (1992): January-March More Issue