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Medical Journal of Indonesia
Published by Universitas Indonesia
ISSN : 08531773     EISSN : 22528083     DOI : 10.13181
Core Subject : Health,
Medicine & Pharmacology
This quarterly medical journal is an official scientific journal of the Faculty of Medicine Universitas Indonesia in collaboration with German-Indonesian Medical Association (DIGM) Indexed in: IMSEAR; CAB Abstracts; Global Health; HINARI; DOAJ; DRJI; Google Scholar; JournalTOCs; Ulrichsweb Global Serial Directory; WorldCat; New Jour; Electronic Journals Library; ISJD Accredited (2013-2018) by DIKTI Kemendikbud Republik Indonesia (No:58/DIKTI/Kep/2013)
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Articles 13 Documents
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Search results for , issue "Vol. 19 No. 4 (2010): November" : 13 Documents clear
The application of correction factors on serum retinol of Indonesia school children
Medical Journal of Indonesia Vol. 19 No. 4 (2010): November
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v19i4.417

Abstract

Aim: Vitamin A deficiency among children is still a public health problem in Indonesia. Serum/plasma retinol concentration is the best indicator in assessing vitamin A status. However, there is growing concern that infection/ inflammation lowers serum  retinol concentration, thus creating potential misinterpretation of vitamin A status, which could affect policy makers in planning suitable nutrition programs targeted at community. The aim of this study was to highlight the importance of applying correction factors, to better interpret serum retinol as a nutritional statusbiomarker.Methods: A cross sectional study involving 54 apparently healthy school children was conducted in East Nusa Tenggara. Height, body weight, concentrations of serum retinol, CRP and AGP were assessed. Based on concentrations of serum CRP and AGP, four infl ammation groups were determined, namely reference,  incubation, early convalescence and late convalescence groups. Correction factor was obtained by dividing serum retinol  concentration of reference group by that of the other three groups. Correction factors were then used to correct serum retinol concentration without any  influence of infection/ inflammation.Results: The prevalence of stunting and underweight were 43% and 22% respectively, but there was no wasting among the school children. Applying correction factor lowered the prevalence of vitamin A defi ciency from 20.4% to 18.5%; thus changing vitamin A defi ciency from a severe public health problem to a moderate public health problem.Conclusion: Correcting serum retinol concentration for the infl uence of infection reduced the apparent severity of vitamin A deficiency. This could affect policy for planning nutrition programs designed for communities. (Med J Indones 2010;  19:258-63)Keywords: correction factor, infection, school children, serum retinol
Gonadothropin-releasing hormone agonist as a treatment of choice for central precocious puberty
Medical Journal of Indonesia Vol. 19 No. 4 (2010): November
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v19i4.418

Abstract

Precocious puberty is defi ned as pubertal development which occurs too early. The age limit in this term is based on the onset of puberty in normal population. Some points have to be taken into account, such as ethnicity, gender, nutritional conditions, and secular trends. In girls, precocious puberty is defi ned by breast development occured before 8 years old. In boys, precocious puberty is defi ned as gonadarche or pubarche before 9 years of age. The clinical course of precocious puberty varies widely, ranging from alternating, slowly progressive, and rapidly progressive    form. The rapidly progressive forms of idiopathic central precocious puberty need to be treated because it may result in early epiphyseal closure and short fi nal height, and also pyschosocial problems in the affected children and the family. The aims of treatment are to arrest physical maturation, prevent early menarche, and also improve adult height combined with normal body proportions. Gonadotropin releasing hormone analogue is the treatment of choice for central precocious puberty. Gonadotropin releasing horomone analogue has suppressive effect on the pituitarygonadal axis, therefore it suppresses LH secretion. This leads to the return of estradiol and testosterone to prepubertal levels. Treatment using gonadotropin releasing horomone analogue is shown to reduce breast size, pubic hair, ovarian and uterine size in girls, and decrease testicular size in boys. Gonadotropin releasing hormone analogue is effective in halting progression of secondary sexual characteristics development, presenting menstrual cycle, slowing bone-age advancement, and also improving fi nal height. (Med J Indones 2010; 19:287-92)Keywords: gonadache, GRH analogue, pubarche , precocious puberty
Tobacco control policy in Indonesia
Medical Journal of Indonesia Vol. 19 No. 4 (2010): November
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.v19i4.551

Abstract

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