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INDONESIA
Indonesian Journal of Urology
Published by Universitas Airlangga
ISSN : 0853442X     EISSN : 23551402     DOI : 10.32421
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The aim of Indonesian Journal of Urology is to encompass the whole spectrum of urology. The journal publishes papers on a wide range of urological issues such as oncology, functional urology, reconstructive urology, laparoscopy, robotic surgery, endourology, female urology, andrology, pediatric urology, and sexual medicine. We welcome authors for original article (research), review article, interesting case reports, special article, clinical practices, and medical illustrations that focus on the clinical area of urology.
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Articles 36 Documents
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Search results for , issue "Vol 27 No 2 (2020)" : 36 Documents clear
COMPARISON OF PAIN PERCEPTION BETWEEN INTRAVENA TRAMADOL INJECTION WITH PERIPROSTATIC LIDOCAINE INJECTION IN TRANSRECTAL ULTRASONOGRAPHY GUIDED PROSTATE BIOPSY PATIENT Sawal, Zuhri; Djatisoesanto, Wahjoe; Djojodimedjo, Tarmono
Indonesian Journal of Urology Vol 27 No 2 (2020)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v27i2.646

Abstract

Objective: To compare the pain perception between intravenous tramadol administration and PNB technique using lidocaine in TRUS guided prostate biopsy. Material & Methods: The design of this study is a prospective randomized clinical trial. The population of this study is BPH patients who will undergo TRUS guided prostate biopsy procedure according to the indication in our center. Randomization was done for the determination of groups 1 and 2. Group 1 was given tramadol injection 100 mg intravenously, while group 2 was given a local injection of lidocaine periprostatic. The Wong-Baker scale directly determined pain perception during the procedure. Results: The total samples in this study were 20 samples that met the inclusion and exclusion criteria with 10 samples in each group. The lidocaine group had a lower Wong Baker’s pain scale in both probe USG insertion and prostate biopsy than the tramadol group. However, it’s not statistically significant (p=0.089; p=0.125, respectively). Conclusion: The use of intravenous tramadol can be used as an alternative anesthetic/analgesic method in prostate biopsy patients. The pain scale of the intravenous tramadol can be compared with periprostatic lidocaine with lesser complications compared to periprostatic lidocaine.
COMPARISON OF PAIN PERCEPTION BETWEEN INTRAVENA TRAMADOL INJECTION WITH PERIPROSTATIC LIDOCAINE INJECTION IN TRANSRECTAL ULTRASONOGRAPHY GUIDED PROSTATE BIOPSY PATIENT Sawal, Zuhri; Djatisoesanto, Wahjoe; Djojodimedjo, Tarmono
Indonesian Journal of Urology Vol 27 No 2 (2020)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v27i2.646

Abstract

Objective: To compare the pain perception between intravenous tramadol administration and PNB technique using lidocaine in TRUS guided prostate biopsy. Material & Methods: The design of this study is a prospective randomized clinical trial. The population of this study is BPH patients who will undergo TRUS guided prostate biopsy procedure according to the indication in our center. Randomization was done for the determination of groups 1 and 2. Group 1 was given tramadol injection 100 mg intravenously, while group 2 was given a local injection of lidocaine periprostatic. The Wong-Baker scale directly determined pain perception during the procedure. Results: The total samples in this study were 20 samples that met the inclusion and exclusion criteria with 10 samples in each group. The lidocaine group had a lower Wong Baker’s pain scale in both probe USG insertion and prostate biopsy than the tramadol group. However, it’s not statistically significant (p=0.089; p=0.125, respectively). Conclusion: The use of intravenous tramadol can be used as an alternative anesthetic/analgesic method in prostate biopsy patients. The pain scale of the intravenous tramadol can be compared with periprostatic lidocaine with lesser complications compared to periprostatic lidocaine.
THE EFFECT OF VITAMIN E (α- TOCOPHEROL) AS NEPHROPROTECTOR ON BLOOD UREA NITROGEN AND SERUM CREATININE LEVEL OF STRAIN WISTAR RATS AFTER CISPLATIN TREATMENT: IN VIVO STUDY Affandi, Yohan; Djatisoesanto, Wahjoe; Hakim, Lukman
Indonesian Journal of Urology Vol 27 No 2 (2020)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v27i2.649

Abstract

Objective: To analyze the differences in kidney function of Wistar strain rats that received a combination of vitamin E and cisplatin, compared with cisplatin alone. Material & Methods: An experimental prospective study with post-test only control design, using male Wistar strain rats (Rattus norvegicus). Rats were randomized using the simple randomized sampling method. Treatment was given in the form of exposure to cisplatin 5 mg/kg (positive control group), with a combination of vitamin E 100 mg/kg and 200 mg/kg (treatment group), to evaluate its effect on kidney function as measured by blood urea nitrogen (BUN) and creatinine serum. Results: Statistical analysis of Mann Whitney showed that there were no differences in BUN levels in the positive control group (cisplatin 5 mg/kg) against each treatment group (p>0.05). Further analysis showed that there was no significant difference between treatment group 1 (Vitamin E 100 mg/kg) and treatment group 2 (Vitamin E 200 mg/kg). There was no difference in serum creatinine levels in the positive control group compared to a treatment group that received both vitamin E 100 mg/kg and the vitamin E 200 mg/kg (p>0.05). further analysis revealed no significant difference in serum creatinine levels between the group that receives vitamin E 100 mg/kg and 200 mg/kg. Conclusion: Vitamin E at doses of 100 mg/kg and 200 mg/kg did not have the nephroprotective feature in cisplatin-exposed Wistar rats.
THE EFFECT OF VITAMIN E (α- TOCOPHEROL) AS NEPHROPROTECTOR ON BLOOD UREA NITROGEN AND SERUM CREATININE LEVEL OF STRAIN WISTAR RATS AFTER CISPLATIN TREATMENT: IN VIVO STUDY Affandi, Yohan; Djatisoesanto, Wahjoe; Hakim, Lukman
Indonesian Journal of Urology Vol 27 No 2 (2020)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v27i2.649

Abstract

Objective: To analyze the differences in kidney function of Wistar strain rats that received a combination of vitamin E and cisplatin, compared with cisplatin alone. Material & Methods: An experimental prospective study with post-test only control design, using male Wistar strain rats (Rattus norvegicus). Rats were randomized using the simple randomized sampling method. Treatment was given in the form of exposure to cisplatin 5 mg/kg (positive control group), with a combination of vitamin E 100 mg/kg and 200 mg/kg (treatment group), to evaluate its effect on kidney function as measured by blood urea nitrogen (BUN) and creatinine serum. Results: Statistical analysis of Mann Whitney showed that there were no differences in BUN levels in the positive control group (cisplatin 5 mg/kg) against each treatment group (p>0.05). Further analysis showed that there was no significant difference between treatment group 1 (Vitamin E 100 mg/kg) and treatment group 2 (Vitamin E 200 mg/kg). There was no difference in serum creatinine levels in the positive control group compared to a treatment group that received both vitamin E 100 mg/kg and the vitamin E 200 mg/kg (p>0.05). further analysis revealed no significant difference in serum creatinine levels between the group that receives vitamin E 100 mg/kg and 200 mg/kg. Conclusion: Vitamin E at doses of 100 mg/kg and 200 mg/kg did not have the nephroprotective feature in cisplatin-exposed Wistar rats.
THE EFFECT OF VITAMIN E (α-TOCOPHEROL) TO TNF-α SERUM LEVELS IN WISTAR WHITE STRAIN RATS EXPOSED TO CISPLATIN Muhammad Shidqy, Eldien; M. Soebadi, Doddy; Hakim, Lukman
Indonesian Journal of Urology Vol 27 No 2 (2020)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v27i2.651

Abstract

Objective: To analyze the protective effect of vitamin E on TNF-α levels in white Wistar strains exposed to Cisplatin. Material & Methods: The design of this study was an experimental laboratory with post-test only control group design, with the evaluation of TNF-α levels carried out after the animals were treated. The grouping of experimental animals was carried out by randomization. This study using male Wistar white rats as samples. The control group in this study included a negative control group (CN), which was given an injection of 1 cc intravenous normal saline 0.9% on the 7th day as a placebo, then on the 10th day the blood sample was taken. The positive control group (CP), which was given cisplatin treatment at a dose of 5 mg/kg intraperitoneally, once on the 7th day. Treatment group (P1) was treated using cisplatin 5 mg/kg intra-peritoneally and Vitamine E 100 mg/KgBW, and Treatment group (P2) was treated using cisplatin 5 mg/kg intra-peritoneally and Vitamine E 200 mg/KgBW. Blood samples were taken on the 10th day, intra-cardiac and TNF-α levels were analyzed using ELISA. Results: There were significant differences in the mean TNF-α levels in the negative control group for all treatment groups with a p-value <0.05. There was also a significant difference in TNF-α levels in the positive control group for treatment group 1 and treatment 2 with p<0.05. On the other hand, further analysis showed that there was no significant difference between treatment group 1 and treatment group 2 (p>0.05). Conclusion: TNF-α levels in mice given cisplatin was much higher compared with the control group. Vitamin E 100 and 200 mg/kgBW cause a decrease in TNF-α protein levels in mice injected with cisplatin when compared with controls. There is no difference in TNF-α levels in mice receiving vitamin E at doses of 100 and 200 mg/kgBW
THE EFFECT OF VITAMIN E (α-TOCOPHEROL) TO TNF-α SERUM LEVELS IN WISTAR WHITE STRAIN RATS EXPOSED TO CISPLATIN Muhammad Shidqy, Eldien; M. Soebadi, Doddy; Hakim, Lukman
Indonesian Journal of Urology Vol 27 No 2 (2020)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v27i2.651

Abstract

Objective: To analyze the protective effect of vitamin E on TNF-α levels in white Wistar strains exposed to Cisplatin. Material & Methods: The design of this study was an experimental laboratory with post-test only control group design, with the evaluation of TNF-α levels carried out after the animals were treated. The grouping of experimental animals was carried out by randomization. This study using male Wistar white rats as samples. The control group in this study included a negative control group (CN), which was given an injection of 1 cc intravenous normal saline 0.9% on the 7th day as a placebo, then on the 10th day the blood sample was taken. The positive control group (CP), which was given cisplatin treatment at a dose of 5 mg/kg intraperitoneally, once on the 7th day. Treatment group (P1) was treated using cisplatin 5 mg/kg intra-peritoneally and Vitamine E 100 mg/KgBW, and Treatment group (P2) was treated using cisplatin 5 mg/kg intra-peritoneally and Vitamine E 200 mg/KgBW. Blood samples were taken on the 10th day, intra-cardiac and TNF-α levels were analyzed using ELISA. Results: There were significant differences in the mean TNF-α levels in the negative control group for all treatment groups with a p-value <0.05. There was also a significant difference in TNF-α levels in the positive control group for treatment group 1 and treatment 2 with p<0.05. On the other hand, further analysis showed that there was no significant difference between treatment group 1 and treatment group 2 (p>0.05). Conclusion: TNF-α levels in mice given cisplatin was much higher compared with the control group. Vitamin E 100 and 200 mg/kgBW cause a decrease in TNF-α protein levels in mice injected with cisplatin when compared with controls. There is no difference in TNF-α levels in mice receiving vitamin E at doses of 100 and 200 mg/kgBW

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