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INDONESIA
Jurnal Kesehatan Andalas
Published by Universitas Andalas
ISSN : 23017406     EISSN : 26151138     DOI : -
Core Subject : Health,
Health Professions
Jurnal Kesehatan Andalas merupakan Jurnal yang diterbitkan oleh Fakultas Kedokteran Universitas Andalas.
Arjuna Subject : -
Articles 42 Documents
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Search results for , issue "Vol 3, No 2 (2014)" : 42 Documents clear
Peran Kemokin dalam Patogenesis Rinitis Alergi Effy Huriyati; Bestari J Budiman; Ricki Octiza
Jurnal Kesehatan Andalas Vol 3, No 2 (2014)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v3i2.101

Abstract

AbstrakLatar belakang: Rinitis alergi merupakan penyakit dengan insiden yang cukup tinggi diseluruh dunia dengan prevalensi yang semakin meningkat setiap tahun. Patogenesis rinitis alergi melibatkan reaksi imun yang cukup komplek. Tujuan: Mengetahui peranan kemotaktik sitokin (Kemokin) dalam patogenesis rinitis alergi. Tinjauan pustaka: Kemokin sebagai kemotaktik sitokin berperan dalam semua tahap reaksi alergi. CC kemokin merupakan subfamili kemokin yang berperan dalam reaksi alergi. Kemokin bekerja pada permukaan sel-sel inflamasi berikatan dengan reseptor. CCR3 merupakan reseptor dengan kadar tertinggi yang ditemukan pada permukaan eosinofil dan eotaxin sebagai ligand yang spesifik bagi CCR3. Kesimpulan: Eotaxin dan reseptor CCR3 adalah faktor yang paling menonjol dalam patogenesis rinitis alergi yang melibatkan eosinophilKata kunci: Reaksi alergi, Th2, CC Kemokin, eosinofil, CCR3 AbstractBackground: Allergic rhinitis such a disease with high incidence among the world and its prevalence appears to be increasing every year. The pathogenesis of allergic rhinitis commit complex imunological reaction. Purpose: To know the role of chemotactic cytokine (chemokine) in pathogenesis of allergic rhinitis. Literature review: Chemokine as a chemotactics cytokine participate to all allergic reaction stage. CC chemokines were subfamilial chemokines which have role in allergic reaction. They working by binding with receptor on the surface of inflamatory cells. CCR3 is the receptor with the highes level could be found on eosinophil cell membran and eotaxin was the spesific ligand to itt. Conclusion: Eotaxin and CCR3 are the major factor in pathogenesis of allergic rhinitis which is involve eosinophil.Keywords: Allergic reaction, Th2, CC Chemokines, eosinophil, CCR3
Perbedaan Perlukaan Genitalia Perempuan Berdasarkan Posisi Persetubuhan Diluar Perkawinan di RSUP Dr. M. Djamil Padang Tahun 2010-2012 Ami Tri Nursasmi; Rika Susanti; Hafni Bachtiar
Jurnal Kesehatan Andalas Vol 3, No 2 (2014)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v3i2.37

Abstract

AbstrakPersetubuhan diluar perkawinan menjadi suatu masalah di pengadilan karena banyaknya perbedaan pendapat mengenai perlukaan selaput dara. Penelitian ini dilakukan untuk membuktikan perbedaan perlukaan selaput dara tersebut yang dilakukan di RSUP Dr. M. Djamil Padang, mencakup karakteristik korban, perlukaan selaput dara, perlukaan dibagian tubuh lain, dan hubungan perlukaan berdasarkan posisi persetubuhan. Penelitian ini bersifat analitik. Sampel sebanyak 81 responden yang telah mengalami persetubuhan diluar perkawinan. Data diambil dari Bagian Forensik RSUP Dr. M. Djamil Padang periode bulan Juli 2010 sampai dengan Juli 2012. Data diolah dengan menggunakan program komputer dan dianalisis melalui uji chi square. Dari 81 subjek penelitian ditemukan hasil tertinggi berupa usia korban adalah 12-18 tahun (62%), pekerjaan sebagai pelajar (56%), alamat berada di Kecamatan Koto Tangah (20%), hubungan korban dengan pelaku sebagai pacar (48%), perlukaan selaput dara pada arah jarum jam selain 5 dan 7 (47%), tidak tampaknya tanda-tanda kekerasan dibagian tubuh lain (81%). Dari uji chi square didapatkan nilai p = 0,585 dengan demikian Ha penelitian ditolak (p>0,05). Penelitian ini dapat disimpulkan bahwa tidak terdapatnya hubungan yang signifikan antara perlukaan selaput dara dengan posisi persetubuhan diluar perkawinan.Kata kunci: Persetubuhan, selaput dara, perlukaanAbstractNon marital sexual activity has been being a big issues on the court because there are contradictions argument about wounded hymen. This research is conducted to prove the difference of that wound occurs in public hospital of dr.M.Djamil Padang, including the victim’s character, hymen’s injury, another injury in other parts body, and the connection of each injuries based on intercourse position. This research having an analitical nature. 81 respondents of sample who done non marital sexual activity. The data taken from Forensics division of RSUP dr.M.Djamil Padang for period of July 2010 to July 2012. The data be treated with computer program and analyzed by chi square test. From 81 subjects of research found the highest result are the age of victim in range 12-18 years old (62%), the occupation as a student (56%), the address in Koto Tangah sub district (20%), the relation of victim and executants as a boyfriend (48%), wounded hymen injured in except area 5 and 7 (47%), no other visible injuries due to violation in other parts of the victim’s bodies (81%). From chi square test, the vale of p=0,585 as the result and the conclusion this research of Ha rejected (p>0,05)]. The conclusion of this research, there is no significant relationship between wounded hymen injured with non marital sexual activity.Keywords:sexual intercourse, hymen, injury

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