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INDONESIA
Jurnal Farmasi Klinik Indonesia
Published by Universitas Padjadjaran
ISSN : 23375701     EISSN : 2337 5701     DOI : -
Core Subject :
Indonesian Journal of Clinical Pharmacy (IJCP) is a scientific publication on all aspect of clinical pharmacy. It published 4 times a year by Clinical Pharmacy Master Program Universitas Padjadjaran to provide a forum for clinicians, pharmacists, and other healthcare professionals to share best practice, encouraging networking and a more collaborative approach in patient care. Indonesian Journal of Clinical Pharmacy is intended to feature quality research articles in clinical pharmacy to become scientific guide in fields related to clinical pharmacy. It is a peer-reviewed journal and publishes original research articles, review articles, case reports, commentaries, and brief research communications on all aspects of Clinical Pharmacy. It is also a media for publicizing meetings and news relating to advances in Clinical Pharmacy in the regions.
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Search results for , issue " Vol 3, No 2 (2014)" : 5 Documents clear
Pengaruh Penyimpanan terhadap Sterilitas Peralatan Pakai Ulang di Ruang Neurosurgical Critical Care Unit di Salah Satu Rumah Sakit di Bandung Budiman, Arif; Rindiantika, Yokaniza; Kurniawan, Insan S.; Hegandari, Hegandari
Indonesian Journal of Clinical Pharmacy Vol 3, No 2 (2014)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.532 KB) | DOI: 10.15416/ijcp.2014.3.2.61

Abstract

Neurosurgical Critical Care Unit (NCCU) merupakan ruang perawatan intensif yang memiliki nilaiprevalensi Infeksi Rumah Sakit (IRS) yang tinggi sebesar 16,7%. Hal tersebut dikarenakan NCCUdigunakan untuk merawat pasien sakit berat dan kritis pascabedah saraf. Tujuan penelitian ini adalah untukmengetahui sterilitas peralatan pakai ulang pada ruang NCCU dibandingkan dengan ruang penyimpananCentral Sterile Supply Department (CSSD). Pengujian sterilitas meliputi uji sterilitas media, uji fertilitasmedia serta uji peralatan pakai ulang menggunakan metode transport swab. Pengujian dilakukan selama28 hari, kemudian diinterpretasikan menggunakan perhitungan odds ratio. Hasil menunjukkan bahwaRuang NCCU pada hari ke-7 ditemukan peralatan yang terkontaminasi sedangkan pada ruang CSSDbaru ditemukan pada hari ke-28. Hal ini menandakan bahwa ruangan CSSD lebih steril dibandingkanruang penyimpanan NCCU. Walaupun tingkat sterilitas ruang CSSD lebih tinggi dibandingkan denganruang NCCU, tidak memberikan pengaruh yang signifikan terhadap sterilitas peralatan pakai ulang.Kata kunci: CSSD, IRS, NCCU, peralatan pakai ulang, sterilitasEffect of Storage to Reusable Equipment Sterility in Neurosurgical CriticalCare Unit at a Hospital in BandungAbstractNeurosurgical Critical Care Unit (NCCU) is an intensive care room which has a high prevalenceof Hospital Infection about 16.7%. That is because NCCU is used to treat patient post neurosurgry.This research aims to determine the sterility of reusable equipment from NCCU, compared to CentralSterile Supply Department (CSSD). The sterility test included sterility test of medium, fertility test andtrasnport swab method for reuseable equipment test. Tests carried out for 28 days, then interpreted usingodds ratio calculation. The result showed that NCCU on day 7 was contaminated, while CSSD wascontaminated on day 28. This indicated that CSSD more sterile than NCCU. Although the sterility ofCSSD higher than NCCU, did’nt have a significant effect on the sterility of reusable equipment.Key words: CSSD, hospital infection, NCCU, reusable equipment, sterility
Penggunaan Daftar Tilik (Checklist) sebagai Panduan Read-Back Mengurangi Potensi Risiko Medication Error Maharjana, Ida Bagus N.; Kuswardhani, Tuty; Purwaningsih, Cok I. I.
Indonesian Journal of Clinical Pharmacy Vol 3, No 2 (2014)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (848.443 KB) | DOI: 10.15416/ijcp.2014.3.2.37

Abstract

Rumah sakit sebagai lini terakhir pelayanan kesehatan berkewajiban memberikan pelayanan berkualitas dan beorientasi pada keselamatan pasien, salah satunya tanggung jawab dalam mencegah medication error. Kolaborasi dan komunikasi yang efektif antar profesi dibutuhkan demi tercapainya keselamatan pasien. Read-back merupakan salah satu cara dalam melakukan komunikasi efektif. Before-after study dengan pendekatan TQM PDCA. Sampel adalah catatan obat pada rekam medik pasien rawat inap RSUP Sanglah pada minggu ke-3 bulan Mei (before) dan minggu ke-3 bulan Juli (after) 2013. Perlakuan dengan menggunakan checklist, meminta waktu 2 menit untuk read-back oleh dokter dan perawat seusaivisite bersama. Didapatkan 57 sampel (before) dan 64 sampel (after). Before 45,54% ketidaklengkapan pengisian catatan obat pada rekam medik pasien yang berpotensi risiko medication error menjadi 10,17% setelah perlakuan read-back dengan checklist selama 10 minggu, dengan pencapaian 77,78% berdasarkan pendekatan TQM PDCA. Panduan read-back menggunaan daftar tilik (checklist) sebagai komunikasi efektif dapat menurunkan ketidaklengkapan pengisian catatan obat pada rekam medik yang berpotensi risiko medication error, 45,54% menjadi 10,17%.Kata kunci: Checklist, medication error, read-backChecklist Usage as a Guidance on Read-Back Reducing the Potential Risk of Medication ErrorHospital as a last line of health services shall provide quality service and oriented on patient safety, one responsibility in preventing medication errors. Effective collaboration and communication between the profession needed to achieve patient safety. Read-back is one way of doing effective communication. Before-after study with PDCA TQM approach. The samples were on the medication chart patient medical records in the 3rd week of May (before) and the 3rd week in July (after) 2013. Treatment using the check list, asked for time 2 minutes to read-back by the doctors and nurses after the visit together. Obtained 57 samples (before) and 64 samples (after). Before charging 45.54% incomplete medication chart on patient medical records that have the potential risk of medication error to 10.17% after treatment with a read back check list for 10 weeks, with 77.78% based on the achievement of the PDCA TQM approach. Checklistusage as a guidance on Read-back as an effective communication can reduce charging incompletenessdrug records on medical records that have the potential risk of medication errors, 45.54% to 10.17%.Key words: Checklist, medication error, read-back
Evaluasi Penggunaan dan Efektivitas Antibiotik Profilaksis pada Pasien Bedah Sesar di Rumah Sakit Surakarta Tahun 2010 Mutmainah, Nurul; Setyati, Puri; Handasari, Niken
Indonesian Journal of Clinical Pharmacy Vol 3, No 2 (2014)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (234.399 KB) | DOI: 10.15416/ijcp.2014.3.2.44

Abstract

Penggunaan antibiotik profilaksis pada operasi bedah sesar dapat mengurangi risiko infeksi yangberhubungan dengan komplikasi dan infeksi pascaoperasi. Penelitian ini bertujuan untuk mengetahuigambaran dan ketepatan penggunaan serta efektivitas antibiotik profilaksis pada pasien bedah sesar padadua rumah sakit di Surakarta tahun 2010. Penelitian ini termasuk penelitian deskriptif dengan pengambilandata rekam medis secara retrospektif. Analisis dilakukan terhadap penggunaan antibiotik yang meliputiketepatan antibiotik dibandingkan dengan ketepatan dosis dan  waktu pemberian berdasarkan standar WHO. Sebanyak 200 pasien yang diteliti, ditemukan 76% berusia 20–35 tahun, usia kehamilan sudah cukup bulan (90,5%), lama perawatan di rumah sakit lebih dari 5 hari (46,5%), dan indikasi terbanyakbedah sesar adalah ketuban pecah dini (29%). Antibiotik profilaksis yang digunakan adalah ampisilin(24%), ampisilin-sulbaktam (23%), seftriakson (19,5%), sefotaksim (16%), amoksisilin-klavulanat(11%), dan  sefazolin (6,5%). Ditemukan kesesuaian pemilihan obat dengan standar WHO (30,5%),yang meliputi tepat dosis (6,5%) dan tepat waktu pemberian (52%). Penggunaan antibiotik 100% efektifuntuk mencegah luka infeksi setelah operasi.   Kata kunci: Antibiotik, bedah sesar, profilaksisEvaluation of the Use and Effectiveness of Antibiotics for Prophylactic inPatients with Cesarean Section  at Hospitals in Surakarta in 2010AbstractThe use of antibiotics for prophylactic in sectio cesarean can reduce the risk of infection-relatedcomplications and postoperative infections. This study aims to describe and evaluate the usage  and theeffectiveness of prophylactic antibiotics in cesarean section  patients in two hospitals in Surakarta inyear 2010. The study used retrospective data from medical records. The analysis was then conducted onthe use of antibiotic including the appropriateness of antibiotic (compare to the standard of WHO), theappropriateness of dose and the time of administration. The data from two hundred of patients  showedthat 76% of patients were between 20–35 years old and the patients with aterm pregnancy were 90.5%,46.5% of patients had the length of stay in hospital more than 5 days and 29% of cesarean deliveryindicated by amniotic premature rupture. Antibiotics that used for prophylactic were ampicillin (24%),ampicillin-sulbactam (23%), ceftriaxone (19.5%), cefotaxime (16%), amoxicillin-clavulanate (11%),and cefazolin (6.5%). It was found that 30,5% of drugs were selected based on standard,  6.5% of drugswere given in the appropriate  dose and 52% of drugs were administrated on-time. In conclusion, theantibiotics are 100% effective to prevent the incidence of surgical wound infection.Key words: Antibiotics, cesarean section, prophylactic
A Case Report: Red Skin Syndrome- as the Rebound Effect of Using a Long Term Potent Topical Corticosteroid Octaviani, Cristine D.
Indonesian Journal of Clinical Pharmacy Vol 3, No 2 (2014)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (195.428 KB) | DOI: 10.15416/ijcp.2014.3.2.50

Abstract

31 years old male suffered from a rare skin disorder, diagnosed of red skin syndrome. Seven years ago, symptoms was begun with a light itching on skin area of body as well as face, and visited a general  practitioner,  diagnosed  of  light  allergic  rhinitis.  He  was  prescribed  oral  corticosteroid, methyl prednisolone 4 mg b.i.d and very potent topical corticosteroid, clobetasol. The symptoms was significantly disappeared and being rebound after stopping the prescription. To maintain this rebound effect, for seven years in on-off unhealed conditions, he used topical cream corticosteroid, clobetasol, that fully masked this worst rebound condition. When application of the topical cream was stopped, rebound effect relapsed and even red skin syndrome became worse than before. After20 months of being fully stopped from corticosteroid, the symptoms finally slowly reduced. He almost fully recovered and had a normal life until now December 2013. By this case, we can learn that this red skin syndrome, resulted from side effect of corticosteroid, will be stopped by fully stopping administering orally or topically, and this will take quite long time for skin to recover.Key words: Corticosteroid, rebound, red skin syndrome Studi Kasus: Red Skin Syndrome sebagai Efek Penggunaan Kortikosteroid Topikal dalam Waktu LamaSeorang lelaki berumur 31 tahun menderita gangguan kulit yang didiagnosis sebagai red skin syndrome. Sekitar tujuh tahun yang lalu, gejalanya diawali dengan gatal ringan pada daerah kulit tubuh dan wajah, serta sempat datang berobat ke dokter umum dan didiagnosis sebagai rinitis alergi ringan. Pasien diresepkan kortikosteroid oral methyl prednisolone, 4 mg b.i.d dan krim clobetasol. Dengan pemberian ini dalam waktu tiga hari gejalanya langsung hilang namun kembali muncul ketika pemakaian obat dihentikan, tanpa tapering off. Dalam menjaga keadaan kulitnya, selama kurang lebih tujuh tahun dengan keadaan hilang-kambuh, pasien menggunakan pengganti kortikosteroid oral, yaitu krim topikal kortikosteroid clobetasol yang kemudian dapat menutupi kondisi on-off rebound tersebut. Ketika penggunaan krim topikalnya dihentikan, efek rebound kembali muncul bahkan dengan kondisi yang lebih buruk. Setelah berhenti total 20 bulan dari penggunaan terakhirnya, perlahan gejalanya mereda. Keadaan pasien membaik hingga bulan Desember 2013. Red skin syndrome sebagai efek samping dari pemberian topikal kortikosteroid baik oral maupun topikal pada kasus ini dapat dihentikan total dengan cara menghentikan seluruh pemberian obat dan menunggu waktu cukup lama hingga kulit kembali pulih. Kata kunci: Kortikosteroid, rebound effect, red skin syndrome
Evaluasi Nilai Blood Urea Nitrogen dan Serum Kreatinin pada Pemberian Kemoterapi Paklitaksel-Karboplatin pada Pasien Kanker Serviks Sel Skuamosa Stadium IIB-IIIB Noviyani, Rini; Suwiyoga, Ketut; Dewi, Anak A. A. W. P.; Niruri, Rasmaya; Tunas, I. K.; Budiana, I N. G.
Indonesian Journal of Clinical Pharmacy Vol 3, No 2 (2014)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/ijcp.2014.3.2.55

Abstract

Kemoterapi paklitaksel-karboplatin merupakan salah satu terapi untuk kanker serviks. Toksisitas kemoterapi pada ginjal dapat dinilai menggunakan nilai Blood Urea Nitrogen (BUN) dan serum kreatinin. Pada penelitian potong lintang prospektif ini diperoleh 6 pasien kanker serviks yang memenuhi kriteria penelitian. Pemeriksaan kadar BUN dan serum kreatinin dilakukan sebelum kemoterapi pertama dan sesudah kemoterapi seri ketiga. Rentang waktu kemoterapi pertama ke kemoterapi ketiga adalah tiga minggu. Pengambilan sampel penelitian menggunakan consecutive sampling. Data penelitian dianalisis menggunakan paired test dengan interval kepercayaan 95% dengan SPSS 17.0. Hasil evaluasi nilai BUN dan serum kreatinin sebelum dan sesudah kemoterapi menunjukkan tidak terdapat perbedaan yang bermakna antara sebelum kemoterapi pertama dengan sesudah kemoterapi ketiga (p>0,05). Hasil penelitian ini dapat digunakan dokter sebagai pertimbangan untuk memberikan kemoterapi dengan regimen paklitaksel-karboplatin sesuai prosedur yang berlaku karena terbukti tidak menimbulkan penurunan fungsi ginjal pada pasien kanker serviks skuamosa.Kata kunci: BUN, kanker serviks, kemoterapi, paklitaksel-karboplatin, serum kreatininEvaluation of Blood Urea Nitrogen and Serum Creatinine in Squamous Cell Cervical Cancer Patients Stadium IIb-IIIb Who Receiving Paclitaxel- Carboplatin ChemotherapyPaclitaxel-carboplatin chemotherapy is one of cervical cancer therapy. Renal toxicity from chemotherapy can be assessed using the value of  Blood Urea Nitrogen (BUN) and serum creatinine. In a prospective cross sectional study was obtained 6 cervical cancer patients who met the research criterias. Examination of BUN and serum creatinine performed before first and after third chemotherapy with the interval time of 3 weeks. Sampling method using consecutive sampling. Data were analyzed using paired test with 95% confidence intervals using the SPSS 17.0. BUN and serum creatinine before and after chemotherapy values obtained p>0.05. BUN and serum creatinine values showed no significant difference between before the first chemotherapy to after third chemotherapy. The doctor may consider using this combination chemotherapy in accordance with the procedures in force due to chemotherapy using paclitaxel- carboplatin shown to be effective and not cause renal toxicity in squamous cervical cancer patients.Key words: BUN, cervical cancer, chemotherapy, paclitaxel-carboplatin, serum creatinine

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