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INDONESIA
Majalah Kedokteran Gigi Indonesia
Published by Universitas Gadjah Mada
ISSN : 24600164     EISSN : 24422576     DOI : https://doi.org/10.22146/majkedgiind.36959
Core Subject : Health,
Dentistry
Arjuna Subject : -
Articles 12 Documents
 1   2 
Search results for , issue "Vol 9, No 2 (2023): August" : 12 Documents clear
Evaluation of viscosity and pH of Zingiber officinale var. officinale juice in mouthwash formulation Stefani, Rosita; Vanessa, Gisela Ellenia; Fibryanto, Eko
Majalah Kedokteran Gigi Indonesia Vol 9, No 2 (2023): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.82071

Abstract

Zingiber officinale var. officinale juice has many benefits, including as a mixture of mouthwash. This research aims to analyze the differences in pH and viscosity values of Zingiber officinale var. officinale-containing mouthwashes with concentrations of 3.125%, 6.25%, and 12.5% on days 0, 14, 28, 42, and 56. Zingiber officinale var. officinale-containing mouthwashes with concentrations of 3.125%, 6.25%, and 12.5% were mixed with propylene glycol, PEG-40 hydrogenated castor oil, oleum menthae, benzoic acid, sodium benzoate, calcium lactate, sorbitol 70% and calcium thiocyanate. The formulation was measured with a pH meter (Jenway, United Kingdom) and a viscometer (Brookfield, Massachusetts) for 56 days. pH data was analyzed using GLM repeated measures ANOVA and one-way ANOVA (p < 0.05). Viscosity data was analyzed using GLM repeated measured ANOVA and the Kruskal-Wallis test (p < 0.05). The pH value of the 3.125% formulation showed significant difference for 56 days in the range of 5.50-5.61. The viscosity value showed no significant difference for 56 days in the range of 3.03-3.09 cP. The pH and viscosity value of the 6.25% formulation showed no significant difference for 56 days with pHs of 5.78-5.83, while the viscosity is 3.12-3.13 cP. The pH and viscosity value of the 12.5% formulation showed no significant difference for 56 days with pHs of 4.90, while the viscosity was 3.43-3.50 cP. The Zingiber officinale var. Officinale mouthwash formulation with a concentration of 3.125% was unstable, but it had the lowest viscosity value and was stable for 56 days. The pH and viscosity value of the 6.25% and 12.5% formulations were stable for 56 days. The highest pH value was in the 6.25% formulation.
Differences in levels of bone morphogenetic protein-2 in periodontitis patients with and without type 2 diabetes mellitus Pritama, Muhammad Fauzi Adityawan; Syaify, Ahmad; Suryono, Suryono
Majalah Kedokteran Gigi Indonesia Vol 9, No 2 (2023): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.83286

Abstract

Periodontitis is characterized by gingival bleeding, periodontal pocket formation, damage to the connective tissue attachment, and alveolar bone resorption. One of the risk factors that can increase the occurrence of periodontitis is diabetes mellitus (DM). In Indonesia, the incidence and prevalence of periodontitis are higher in patients with type 2 DM. In the present study, BMP-2 expression in periodontitis patients with and without type 2 DM was evaluated. We performed a descriptive analytical cross-sectional study in 40 respondents with stages II-III grades B-C chronic periodontitis. They were divided into a chronic periodontitis group with type 2 DM and a chronic periodontitis group without DM. Crevicular fluid of the gingival sulcus of the central maxillary anterior teeth from each respondent was taken using paper points for 5 minutes and placed in an Eppendorf tube. Each tube was labelled according to its group. All of the samples were examined by BMP-2 ELISA kit and measured by BioRad microplate reader with a wavelength of 450 nm. Data were analysed using SPSS 16.0 program. The independent sample t-test was used to compare the BMP-2 among two groups. The results of the study revealed the BMP-2 level in periodontitis patients with type 2 DM was 63.1 pg/ml, while in periodontitis patients without DM was 66.8 pg/ml. BMP-2 levels in periodontitis patients with type 2 DM were significantly lower than those in periodontitis patients without DM (p < 0.05).

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