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WMJ (Warmadewa Medical Journal)
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Published by Universitas Warmadewa
ISSN : 25274627     EISSN : 25799010     DOI : doi.org/10.22225/wmj
Core Subject : Health,
Health Professions Medicine & Pharmacology
WMJ (Warmadewa Medical Journal) is the Journal of Medicine & Health, contains scientific articles (Original/ Research Articles, Review Articles, Case Reports) by academic community of the Faculty of Medicine and Health Sciences Warmadewa University, other Faculties of Medicine and Health Sciences and other related Institutions. It is the medium for hardskill and softskills development as an integral part of the Tri Dharma Perguruan Tinggi (Education, Research, Public Service) and health services in the forms of media of communication, information, scientific education, as a subsystem of Medicine and Health holistic and comprehensive services.
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Articles 5 Documents
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Search results for , issue "Vol 2 No 1 (2017): Mei 2017" : 5 Documents clear
Penerapan Mind Map pada Mahasiswa Blok Special Topic (Pirene) di Fakultas Kedokteran dan Ilmu Kesehatan (FKIK) Universitas Warmadewa Putu Nita Cahyawati; Putu Alit Sudarsana Sudarsana
WMJ (Warmadewa Medical Journal) Vol 2 No 1 (2017): Mei 2017
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.2.1.81.19-25

Abstract

Mind map merupakan metode penyusunan catatan demi mengoptimalkan seluruh potensi otak. Metode ini memungkinkan daftar informasi yang panjang dialihkan menjadi diagram yang dikombinasikan dengan berbagai warna, simbol, dan gambar, sehingga memudahkan otak dalam menyerap. Penerapan metode ini dalam pembelajaran diharapkan dapat membantu mahasiswa mencapai tujuan belajar. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh penerapan metode pembelajaran mind map terhadap motivasi dan kelulusan mahasiswa Fakultas Kedokteran dan Ilmu Kesehatan (FKIK) Universitas Warmadewa pada Blok Special Topic (Pirene). Selama Blok berlangsung setiap mahasiswa membuat mind map sesuai dengan kasus (pemicu) dalam Modul Blok. Motivasi mahasiswa terhadap penerapan mind map dievaluasi menggunakan kuesioner dan evaluasi kelulusan mahasiswa ditentukan menggunakan nilai ujian akhir menggunakan multiple choice question (MCQ). Rerata peningkatan motivasi belajar mahasiswa melalui penerapan mind map sebesar 82,2%. Kelulusan first taker mahasiswa mencapai 84,48% dengan nilai A sebesar 53,45% dan nilai B sebesar 31,03%. Mahasiswa dengan nilai mind map assessment rubric (MMAR) >1000  ternyata 100% lulus ujian akhir, walaupun masih belum jelas adanya korelasi langsung antara nilai MMAR dengan kelulusan mahasiswa  tersebut. Penerapan metode pembelajaran mind map pada Blok Special Topic (Pirene) berdampak baik terhadap peningkatan motivasi belajar mahasiswa dan kelulusan first taker mahasiswa.Kata Kunci: mind map, Blok Special Topic (Pirene), motivasi belajar, kelulusan [The Application of Mind Map on College Student Block Special Topic (Pirene) in Faculty of Medicine and Health Science, Warmadewa University]Mind map is a note-taking strategy to optimize the brain potential. This method allows a long list of information, transferred into a diagram combined with a variety of colors, symbols, and images, making it easier for the brain to absorb information. Application of this method as a learning strategy is expected to help students achieve the learning objectives. The aim of this study was to determine the effect of the application mind map as learning methods toward motivation and graduation in medical faculty students on Block Special Topic (Pirene). During the Block takes place, each student create a mind map accordance with the case (triggers) in Block Module. Motivation of students to the application of the mind map was evaluated using questionnaires and evaluation of student graduation is determined using the value of the summative MCQ exam. The mean of student motivation to learn through the implementation of a mind map was 82.2%. First taker graduation of students reaching 84.48% with a value of A was 53.45% and the value of B was 31.03%. Students with grades MMAR> 1000 was 100% pass the exam summative, although it is still not clear the direct correlation between the value of the MMAR with students graduation. The application of mind map on the Block Special Topic (Pirene) works to increase the student motivation to learn and graduation of first taker students.Keywords: mind map, Block Special Topic (Pirene), motivation to learn, graduation
KarakteristikPasien Preeklampsiadan Eklampsia di Rsud dr. T.C. Hillers Maumere Periode Januari – Juni 2016 I Nyoman Rake Genatra Sardeva
WMJ (Warmadewa Medical Journal) Vol 2 No 1 (2017): Mei 2017
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.2.1.72.26-32

Abstract

Preeklampsia dan eklampsia merupakan penyebab terbanyak kedua kematian ibu setelah perdarahan dimana preeklampsia berat dan eklampsia. Di provinsi Nusa Tenggara Timur khususnya di kabupaten Sikka, belum ada data ataupun laporan mengenai kejadian preeklampsia dan eklampsia. Penelitian ini bertujuan untuk mengetahui gambaran karakteristik pasien yang dirawat dengan preeklampsia dan eklampsia di RSUD dr. TC HILLERS Maumere periode Januari sampai dengan Juni 2016. Rancangan penelitian menggunakan survei deskriptif. Sampel pada penelitian ini diambil dari data sekunder. Setelah data dikumpulkan, kemudian dilakukan analisis data dengan teknik statistik deskriptif. Selama Januari 2016 sampai Juni 2016 didapatkan 112 kasus preklampsia dan eklampsia. Didapatkan kelompok umur ibu 20-35 tahun sebanyak 76 kasus (67,86%), primigravida sebanyak 54 kasus (48,22%), pendidikan SD sebanyak 51 kasus (45,54%), kelompok tidak bekerja sebanyak 95 kasus (84,82%), dan tidak ada riwayat hipertensi pada kehamilan sebelumnya 37 kasus (63,79%).Disimpulkan bahwa kasus preeklampsia dan eklampsia selama pada Januari sampai Juni 2016 adalah 112 kasus (9,54%), dari kasus tersebut sebanyak 67% terjadi pada umur 20-35 tahun, 48% pada primigravida, 45,54% dengan pendidikan SD, 84,82% tidak bekerja, dan 63% tidak memiliki riwayat hipertensi pada kehamilan sebelumnya.Kata Kunci: preeklampsia, eklampsia, karakteristik Preeclampsia and eclampsia is the most common cause of maternal death after bleeding. In Indonesia, severe preeclampsia and eclampsia is the leading cause of maternal death ranges from 1.5% - 25%, while the infant mortality between 45 percent to 50 percent. The magnitude of this problem not only because of preeclampsia affects the mother during pregnancy and childbirth, but also cause in postpartum. In East Nusa Tenggara province, especially in Sikka district, there is no data or reports on the prevalence or general description about incidence of preeclampsia and eclampsia. This research aimed to describe characteristics of patient with preeclampsia and eclampsia in Dr. T.C. Hillers Hospital Maumere between January to june 2016. This research was a descriptive survey. The sample in this study is taken from secondary data. After data is collected, then analyzed the data using statistical descriptive technique. During Januari – June 2016 there were 112 case of preeclampsia and eclampsia. The highest frequency in maternal age group 20-35 years old 76 case (67.86%), primigravida 54 case (48.22%), primary school  51 case (45.54%),  unemployed 95 case (84.82%), and did not have history of hypertension in a previous pregnancy 37 case (63.79%) Concluded thatcases of preeclampsia and eclampsia from January until June 2016 were112 cases, with maternal age of 20–30 years old 67.86%, primigravida parity 48.22%, level of education is primary school 45.54%, unemployed 84.82%, and without history of hypertension in a previous pregnancy (63,79%).Keywords: preeclampsia, eclampsia, characteristics
Peranan Laboratorium dalam Prevention of Mother to Child Transmission (PMTCT) HIV Sri Ratna Dewi; Umi S. Intansari
WMJ (Warmadewa Medical Journal) Vol 2 No 1 (2017): Mei 2017
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.2.1.74.33-43

Abstract

Human Immunodeficiency Virus (HIV) adalah retrovirus RNA yang dapat menyebabkan penyakit klinis, yaitu Acquired Immunodeficiency Syndrome (AIDS). Transmisi virus dari ibu ke anak (mother to child transmission/MTCT) dapat terjadi melalui darah maternal, sekresi saluran genital, dan ASI. Risiko penularan HIV dari ibu ke bayi dapat ditekan hingga 2% dengan program PMTCT. Tulisan ini bertujuan untuk memaparkan tentang peran laboratorium dalam mendukung program PMTCT HIV. Dalam hal ini laboratorium memegang peranan yang penting dalam mendeteksi HIV secara dini dan diikuti dengan evaluasi. Untuk menentukan bayi tidak mengidap HIV, diperlukan minimal dua kali pemeriksaan polymerase chain reaction (PCR) RNA HIV dengan hasil negatif, yaitu pada usia 4-6 minggu dan pada usia 4-6 bulan. Pada saat bayi berusia 18 bulan dilakukan pemeriksaan antibodi terhadap HIV dengan cara Enzyme-linked Immunosorbent Assay (ELISA) untuk konfirmasi. Laboratorium memegang peranan penting dalam melakukan deteksi dini HIV serta membantu dalam proses follow up sehingga dapat mendukung program PMTCT.                                                                        Kata kunci: PMTCT, HIV, PCR, ELISA   [Laboratory Role In The Prevention of Mother to Child Transmission (PMTCT) of HIV]The Human Immunodeficiency Virus (HIV) is a RNA retrovirus which causes the clinical disease termed the acquired immunodeficiency syndrome (AIDS). Mother-to-child transmission (MTCT) may occurred because of the intrapartum maternal blood exposure, infected genital tract secretions and during breastfeeding. The aim of this paper is to explain the role of laboratory to support PMTCT program. Laboratory plays an important role in PMTCT, that given the starting point of PMTCT is early detection of HIV and followed by evaluation. To determine the baby does not have HIV, it takes at least two times the HIV RNA PCR with negative results, (at 4-6 weeks of age and at the age of 4-6 months). And then infants examined for HIV antibodies by Enzyme-linked Immunosorbent Assay (ELISA) for confirmation at 18-month-old. Laboratory has an important role to support diagnose of HIV and their follow up, so it can be support PMTCT program.Keywords: PMTCT, HIV, PCR, ELISA
Ekstrak Air Biji Pepaya (Carica Papaya) dapat Menurunkan Kadar Kolesterol Total dan Kadar Serumglutamat Piruvat Transaminase (Sgpt) pada Tikus Putih Jantan Galur Wistar yang Hiperkolesterolemia Legis Ocktaviana Saputri; Bagus Komang Satriyasa; Wayan Putu Sutirta Yasa
WMJ (Warmadewa Medical Journal) Vol 2 No 1 (2017): Mei 2017
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.2.1.73.1-10

Abstract

Hiperkolesterolemia merupakan kelainan metabolisme lemak yang dianggap sebagai faktor yang berkontribusi dalam peningkatan risiko PJK. Biji pepaya diduga memiliki aktivitas hipolipidemik karena mengandung senyawa fitokimia yang berpengaruh pada metabolisme lemak. Penelitian ini menggunakan model eksperimental randomized pretest-posttestcontrol-group design terhadap 30 ekor tikus yang hiperkolesterolemia setelah diinduksi pakan tinggi kolesterol selama 48 hari. Tikus tersebut dibagi ke dalam 3 kelompok yaitu kelompok kontrol negatif (P0), kontrol positif (P1), dan kelompok perlakuan (P2).Aktivitas antihiperkolesterolemik dinilai melalui pengukuran kadar kolesterol total dan SGPT pretest dan posttest. Berdasarkan hasil penelitian, ekstrak air biji pepaya dosis 300 mg/kg/hari mampu menurunkan kadar kolesterol total sebesar 13,39% dan kadar SGPT sebesar 31,4% (p<0,05). Uji One Way Anova menunjukkan bahwa kadar kolesterol total dan SGPT posttest antar kelompok berbeda bermakna (p<0,05). Uji LSD menunjukkan bahwa pemberian ekstrak air biji pepaya dapat secara signifikan menurunkan kadar kolesterol total pada tikus yang hiperkolesterolemia jika dibandingkan dengan kelompok placebo. Kadar tersebut tidak berbeda signifikan dengan kelompok yang diberi simvastatin (beda rerata 0,6 mg/dL; p>0,05). Penurunan kadar SGPT diketahui berbeda bermakna jika dibandingkan kelompok placebo. Hasil tersebut dapat membuktikan bahwa pemberian ekstrak air biji pepaya dapat menurunkan kadar kolesterol total dan SGPT pada tikus putih jantan galur wistar yang hiperkolesterolemia.Kata Kunci: hipekolesterolemia, ekstrak biji papaya, kolesterol total, SGPT. [Aqueous Extract of Papaya (Carica Papaya) Seeds Decreased Total Cholesterol and Alanine Aminotransferase (Alt) Levels in Hypercholesterolemic Male Wistar Rats]Hypercolesterolemic is fat metabolism disorder which contributes to increase the risk of CHD. Papaya seeds issuspected having anti-hipercholesterolemic activity, because contains several phytochemical compounds. This study uses a model of experimental randomized pretest-posttestcontrol-group design in 30 rats that had induced hypercholesterolemia with high cholesterol diet for 48 days. Rats were divided into 3 groups: negative control (P0), positive control (P1), and the treatment group (P2). Antihypercholesterolemic activities were assessed through total cholesterol and ALT pretest and posttest levels. Results of this study has shown that aqueous extract of papaya seeds dose 300 mg/kg/day can reduce total cholesterol by 13.39% and ALT by 31.4% (p<0.05). One Way ANOVA test showed that the levels of total cholesterol and SGPT posttest are significantly different between groups (p<0.05). Further test with LSD showed that the aqueous extract of papaya seeds can significantly reduce total cholesterol when compared to P0. These results do not differ significantly from group that given simvastatin (mean difference 0.6 mg/dL; p>0.05). Decreased levels of ALT are also known significantly different when compared to P0.These result proved that aqueous extract of Carica papaya seeds can decreased total cholesterol and ALT levels in hypercholesterolemic male wistar rats.Keywords: hypercholesterolemic, papaya seeds extract, total cholesterol, ALT
Pemberian Susu Sapi Formula (Enfamil A+1® dan SGM Ananda Presinutri®) Tidak Meningkatkan Estrogen dan Tidak Menurunkan Testosteron pada Bayi Tikus Putih (Rattusnorvegicus) Galur Wistar Jantan Anggrieni Wisni
WMJ (Warmadewa Medical Journal) Vol 2 No 1 (2017): Mei 2017
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.2.1.71.11-18

Abstract

Kandungan fitoestrogen dalam susu formula kedelai dan estrogen pada formula pengganti cair telah terbukti meningkatkan estrogen darah dan menurunkan testosteron. Penekanan testosteron pada masa fetus akan menyebabkan terjadinya berbagai kelainan reproduksi. Dari analisis laboratorium diketahui susu Enfamil A+1® mengandung fitoestrogen sebanyak 1,54 pg/g dan estrogen sebanyak 2,04 pg/g, sedangkan susu SGM Ananda Presinutri® mengandung fitoestrogen sebanyak 1,48 pg/g dan estrogen sebanyak 1,87 pg/g. Penelitian ini bertujuan untuk mengetahui efek pemberian susu sapi formula terhadap kadar hormon estrogen dan testosteron pada bayi tikus putih galur Wistar jantan. Penelitian ini adalah penelitian eksperimental murni post-test only control group design menggunakan 27 ekor bayi tikus jantan yang dibagi secara random menjadi 3 kelompok. Kelompok Kontrol diberi air susu ibu tikus bayi wistar (ASI) ad libitum dan akuabidest. Kelompok Perlakuan 1 (P1) diberi ASI ad libitum dan Enfamil A+1®. Kelompok Perlakuan 2 (P2) diberi ASI ad libitum dan SGM Ananda Presinutri®. Penelitian dilakukan selama 18 hari sejak bayi tikus berusia 3 hari. Kadar hormon estrogen dan testosteron diukur dengan metode Enzyme-linked Immonosorbent Assay (ELISA).  Kadar estrogen rata-rata kelompok kontrol adalah 26,5689 ±4,76152  kelompok P1 adalah 25,5322 ±7,26736 dan kelompok P2 adalah 30,8356 ±6,78459. Kadar estrogen kelompok P1 dan P2 dibanding kontrol adalah tidak berbeda bermakna dengan p=0,194. Kadar tetosteron rata-rata kelompok kontrol adalah 0,4978 ±0,05826 ng/ml, kelompok P1 adalah 0,4800 ±0,07297 ng/ml dan kelompok P2 adalah  0,3856 ±0,18702 ng/ml. Kadar testosteron kelompok P1 dan P2 dibanding kontrol adalah tidak berbeda bermakna dengan nilai p=0,127. Dari penelitian ini disimpulkan bahwa pemberian susu sapi formula Enfamil A+1® maupun SGM Ananda Presinutri® tidak meningkatkan kadar estrogen dan tidak menurunkan testosteron pada bayi tikus putih galur Wistar jantan.  Dalam arti klinis dapat disimpulkan bahwa pemberian ASI bersama susu sapi formula Enfamil A+1® maupun SGM Ananda Presinutri® ditinjau dari efek terhadap kadar hormon estrogen dan testosteron aman diberikan pada bayi tikus putih galur wistar jantan.Kata kunci: Susu sapi formula, Enfamil A+1®, SGM Ananda Presinutri®, estrogen, testosteron. [The Administration of Formula Cowmilk (Enfamil A+1® and SGM Ananda Presinutri®) Did Not Increase Estrogen Level Nor Reduced Testosteron Level in Male Albino Rat (Rattusnorvegicus) Wistar Strain Baby].Phytoestrogenconcentration of soy-based formula milk and estrogen in liquid replacement  formula milk proved to increase blood estrogen and reduce testosterone.  Pressure to testosterone during fetus stage could cause various reproduction disorder. Laboratoryanalysis showed that Enfamil A+1® contained phytoestrogen as much as 1.54 pg/g and estrogen as much as 2.04 pg/g, while SGM Ananda Presinutri® contained phytoestrogen as much as 1.48 pg/g and estrogen as much as 1.87 pg/g. The research was aimed to observe the effect of formula milk administration to the level of estrogen and testosterone level in male albino rat (Rattus norvegicus) Wistar strain baby. The research was true experimental post-test only control group design using 27 male white rat baby agregated randomly into 3 groups.  The control group was fed with breast milk adlibitum and aquabidest.  The first treatment group (P1) was fed with breast milk adlibitum and Enfamil A+1®.  The second treatment group (P2) was fed with breast milkadlibitum and SGM Ananda Presinutri®.  The research was carried out for 18 days since baby rat was 3 days old.  The average concentration of estrogen in control group was 26.5689 ±4.76152 pg/ml, while P1 and P2 group had average concentrations of 25.5322 ±7.26736 pg/ml and 30.8356 ±6.78459 pg/ml respectively.  The estrogen level of P1 and P2 group was not significanly difference than control group with level of p=0.194. Average testosterone levels of control group, P1 group and P2 group were 0.4978 ±0.05826 ng/ml, 0.4800 ±0.0729 ng/ml and 0.3856 ±0.18702 ng/ml respectively.  Testosterone level of P1 and P2 group was not significantly difference with level of p=0.127. The research concluded that administration of Enfamil A+1® formula milk or SGM Ananda Presinutri® formula milk did not increase estrogen level and did not reduce testosterone level to male Wistar strain rat baby. In clinical ways can be concluded that the administrasion of Enfamil A+1® and SGM Ananda Presinutri® was safe in observation of estrogene and testosterone level to male Wistar strain rat baby.Keywords: formula cowmilk, Enfamil A+1®, SGM Ananda Presinutri®, estrogen, testosterone.

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