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Mutiara Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Muhammadiyah Yogyakarta
ISSN : 14118033     EISSN : 26140101     DOI : 10.18196/mm
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Mutiara Medika Fakultas Kedokteran dan Ilmu Kesehatan (MMJKK) Universitas Muhammadiyah Yogyakarta is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health.
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Articles 1 Documents
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Search results for , issue " Vol 18 No 1: January 2018" : 1 Documents clear
Gambaran Leukosit Pro Inflamasi pada Status Asmaticus di RSUD Kebumen Rahayu, Ester Tri; Arjana, Adika Zhulhi; Juwariyah, Juwariyah; Yuantari, Rahma; Irfan, Rozan Muhammad
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 18 No 1: January 2018
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.180108

Abstract

Asma merupakan kondisi penyempitan jalan nafas yang selama ini hanya dianggap sebagai reaksi hipersensitifitas tipe 1 karena pada kondisi lain juga dapat disebabkan oleh inflamasi dan koagulasi. Pada hipersensitifitas tipe 1 terdapat peran neutrofil dan eosinofil dan dalam penelitin ini akan dipetakan fenotip asma berdasarkan aktifitas eosinof dan neutrofil yaitu eosinofilik dan neutrofilik pada serangan akut asma. Penelitian dilakukan dengan desain observasional retrospektif terhadap data sekunder pasien asma dewasa, dalam waktu 1 tahun kebelakang dengan sampel sebanyak 91 orang di RSUD Kebumen. Pengambilan data menggunakan data rekam medis. Analisis data menggunakan uji ANOVA untuk data terdistribusi normal, dan uji rerata Kuskal-Wallis untuk data tidak normal. Karakteristik subyek sejumlah 91 orang, dengan 31 subyek pria dan rerata umur 38 tahun. Delapan puluh empat persen subjek adalah asma derajat ringan, 4 % berat dan sisanya sedang. Pada uji rerata eosinofil dan neutrofil, terdapat berbedaan rerata antar derajat serangan namun tidak signifikan secara statistik. Subyek asma neutrofilik lebih mendomasi dibandingkan eosinofilik. Walaupun begitu, belum dapat diambil kesimpulan hubungan kadar eosinofil dan neutrofil terhadap derajat asma karena belum ada hasil statistik yang signifikan.

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