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Mutiara Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Muhammadiyah Yogyakarta
ISSN : 14118033     EISSN : 26140101     DOI : 10.18196/mm
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Mutiara Medika Fakultas Kedokteran dan Ilmu Kesehatan (MMJKK) Universitas Muhammadiyah Yogyakarta is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health.
Arjuna Subject : -
Articles 22 Documents
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Search results for , issue "Vol 14, No 1 (2014)" : 22 Documents clear
Role Model di Rumah Sakit Pendidikan Wiwik Kusumawati; Siti Aminah Tri Susila Estri; Seshy Tinartayu
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2014): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v14i1.2472

Abstract

Dosen pembimbing klinik pendidikan dokter tahap profesi di rumah sakit sebagai role model yang baik diperlukan untuk mengajarkan sikap perilaku, skills dan knowledge. Studi ini dilakukan untuk merumuskan konsep role model yang diharapkan oleh mahasiswa pendidikan dokter. Disain penelitian ini adalah deskriptif, cross sectional dengan pendekatan kuantitatif dan kualitatif. Metode pengumpulan data dengan kuesioner, wawancara mendalam dengan the general interview guide approach dan observasi dengan insider observer. Lokasi penelitian pada 8 rumah sakit pendidikan FKIK UMY, penentuan sampel secara purposive dengan criterion reference, yaitu mahasiswa yang menjalani stase paling lama di bagian atau mahasiswa di bagian 4 besar pada 8 RS pendidikan. Hasil penelitian menunjukkan, 70% dosen pembimbing klinik pada bagian 4 besar 8 rumah sakit pendidikan FKIK UMY merupakan role model yang baik. Berdasarkan kriteria role model dari Passi, 98% dosen pembimbing klinik menunjukkan clinical skills yang baik, 93% menunjukkan teaching skills dan personal quality yang baik. Terdapat kesesuaian terhadap role model yang diharapkan oleh mahasiswa dari hasil kuesioner, wawancara dan observasi. Rumusan role model yang baik menurut mahasiswa, yaitu mempunyai kemampuan mengajar atau teaching skills yang baik antara lain cukup waktu untuk membimbing, mampu berkomunikasi, me­motivasi mahasiswa belajar, memberikan feedback, dan memiliki pengetahuan yang luas serta up date.In clinical rotation at teaching hospital, the role of clinical teacher as a good role model was needed to teach attitude, skills and knowledge. The aim of this study is to develop concept of role model based on student’s opinions at school of medicine. This study is descriptive, cross sectional using quantitative and qualitative approach. Collecting data method conducted by distributing of questionaires, indepth interview by the general interview guide approach and direct observation by insider observer. This study conducted at 8 teaching hospitals of FKIK UMY. Sampling method by purposived and criterion refer­enced. The respondents was the students who conduct in longest clinical rotation i. e. 4 major departements at 8 teaching hospitals. This study revealed, 70% of clinical teacher in 4 major departements at 8 teach­ing hospitals is good role model. Regarding Passi’s criterias of role model, 98% of clinical teacher show good clinical skills, 93% show good teaching skills and personal quality respectively. There is similar result of concept of role model from questionaires, indepth interview and direct observation. Based on student’s opinions, a good role model should has good teaching skills such as sufficient of time to assist students, good communication skills, can motivate students, give feedback and has both wide and up date of knowledge.
Pengaruh Leptin terhadap Kadar Interleukin 6 Serum Tikus yang Diberi Pakan Tinggi Lemak Daniel Setiawan; Soemardini Soemardini; Rasjad M. Indra
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2014): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v14i1.2474

Abstract

Pada keadaan obesitas, meningkatnya jumlah sel lemak merupakan salah satu penyebab meningkatnya sitokin proinflamasi seperti IL-6. Obesitas dapat dimulai dengan terjadinya resistensi leptin. Penurunan resistensi perifer leptin akan mengembalikan fungsi leptin dalam memecah jaringan lemak sehingga kadar IL-6 dalam serum akan turun. Dalam penelitian ini leptin eksogen diberikan untuk mengatasi resistensi perifer leptin. Penelitian ini bertujuan untuk mengetahui apakah pemberian leptin eksogen dalam jangka pendek dapat mengatasi resistensi perifer leptin. Penelitian eksperimental dengan post test only control group design. Dua puluh lima tikus jantan dibagi menjadi 5 kelompok yaitu kelompok dengan pakan normal, kelompok dengan pakan tinggi lemak, kelompok pakan tinggi lemak dan pemberian leptin dosis 50 ng/ml; 100 ng/ml; dan 200 ng/ml. Tiap kelompok terdiri dari 5 ekor tikus. Setelah diberi pakan tinggi lemak enam puluh hari, tikus diberi injeksi leptin intravena sekali sehari selama 3 hari. Pada hari ke 3 setelah pemberian leptin, tikus dibedah dan diambil darahnya dari aorta. Darah disentrifus, untuk memisahkan serum dengan hematokrit, kemudian diukur kadar IL-6 dalam serum. Tikus yang diberi pakan tinggi lemak kadar IL-6 dalam serum lebih tinggi dibandingkan dengan kelompok yang diberi pakan normal. Tikus yang diberi pakan tinggi lemak dan pemberian leptin mempunyai kadar IL-6 dalam serum yang lebih rendah. Disimpulkan bahwa pemberian leptin eksogen dapat mengatasi resistensi leptin sehingga kadar IL-6 dalam serum menurun.In obesity, the increasing amount of fat cells is one among many factors that causes raise in proinflammatory cytokine such as IL-6. Obesity may begin with leptin resistance. Decline in leptin pe­ripheral resistance will return leptin function in breaking down fat tissues hence the serum concentration of IL-6 will decrease. In this study, exogenous leptin was given to overcome leptin peripheral resistance. This study aims to investigate whether short course of exogenous leptin administration can overcome leptin peripheral resistance. Experimental research with posttest only control group design. Twenty five male mouses were divided into 5 groups which are: group with normal diet, high fat diet, high fat diet with 50 ng/ml leptin administration, high fat diet with 100 ng/ml leptin administration, high fat diet with 200 ng/ ml leptin administration. Every group consists of 5 mouses. After given high fat diet for 60 days, mouses were given intravenous leptin injection once daily for 3 days. On the 3rd day after leptin administration, mice were resected and blood was taken from the aorta. The blood was centrifuged to separate the serum from the hematocrit, and then concentration of IL-6 was measured from the serum. Mouses given high fat diet had higher serum IL-6 concentration compared with control group. Mouses with high fat diet with leptin administration had lower serum IL-6 concentration. It can be concluded that exogenous leptin can overcome leptin resistance, thus serum IL-6 concentration decreases.

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