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Pharmacon
Published by Universitas Muhammadiyah Surakarta
ISSN : 14114283     EISSN : 26855062     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Pharmacon: Jurnal Farmasi Indonesia is a collection of publication journals, covering all aspects of Pharmaceutical sciences, including Technology of Formulations, Excipients Optimization, Extract and Herbal Standardizations, Pharmacological activity determination on natural sources, Drug Synthesize and Development, Molecular Biology, Antibiotic Screening, Metabolite Profiling and Quantification, Clinical Pharmacy, Health and Environmental issues, published by Faculty of Pharmacy, Muhammadiyah University of Surakarta. We look forward to working with pharmaceutical community of researchers as we are intended to serve as a major resource for pharmaceutical information.
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Articles 12 Documents
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Search results for , issue "Vol 14, No 1 (2017)" : 12 Documents clear
Optimum Conditions for Extraction of Antibacterial Compounds from Citrus Aurantifolia Fruit Peel Waste Rima Munawaroh
Pharmacon: Jurnal Farmasi Indonesia Vol 14, No 1 (2017)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v14i1.5779

Abstract

Citrus fruit peel is a major waste in citrus fruit processing industry. The research on extraction activecompounds of Citrus aurantifolia (lime) fruit peel waste and antibacterial activity assay has been done. Theaim of research was to get optimum condition to extract their active compounds which have antibacterialactivity. The dried lime fruit peel was extracted by maceration method using ethanol 48%, 72%, and 96%.The dried and fresh lime fruit peel were also extracted using ethyl acetate. Antibacterial assay was done bydiffusion agar against Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922. The resultshowed that optimal condition to extract antibacterial compound using fresh sample with ethyl acetate assolvent. The ethyl acetate extract of fresh sample was more active against S. aureus than E. coli.
ANTIBACTERIAL ACTIVITY OF ETHANOLIC EXTRACT AND INFUSE OF Bauhinia variegata LEAVES AGAINST Streptococcus pyogenes istiqamatush sholihah
Pharmacon: Jurnal Farmasi Indonesia Vol 14, No 1 (2017)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v14i1.424

Abstract

Bauhinia variegata is a plant that has many virtues and widely grown in Indonesia. Yet the virtues and uses are still limited as the shade and ornamental plant. The purpose of this study is to determine the antibacterial ethanol extract activity and the infuse of Bauhinia Variegata leaves toward Streptococcus pyogenes and to determine the classes of compounds that have antibacterial activity. Bauhinia variegata leaves are extracted by maceration and infundation with 96% ethanol and distilled water. The test method of antibacterial activity is used disc difusson Kirby Bauer methods. The Analyses of the compounds which are contained in the Bauhinia Variegata leaves are done by TLC (Thin Layer Chromatography) and test tubes. The results showed that ethanol extract and infuse of Bauhinia Variegata leaves has no antibacterial activity toward Streptococcus pyogenes. TLC results and test tubes showed that the ethanol extract of Bauhinia Variegata leaves contain tannins, saponins, terpenoids, and alkaloids. While, the infuse of Bauhinia variegata leaves are saponins and alkaloids. Keywords: Bauhinia variegata, antibacterial, Streptococcus pyogenes, maceration, infundation.

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