Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Majalah Obat Tradisional

TradMedJ
Website

Published by Universitas Gadjah Mada

ISSN : 14105918 EISSN : 24069086 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology Public Health

raditional Medicine Journal (Majalah Obat Tradisional), or Trad. Med. J. (ISSN 1410-5918 (print) and ISSN 2406-9086 (online)), is an international scientific journal published by Faculty of Pharmacy, Universitas Gadjah Mada, three times annually. Collaborating with Indonesian Pharmacist Association, Daerah Istimewa Yogyakarta, and we dedicate our journal to researches and development in traditional medicine. The journal receives papers on research laboratory, field research, and case studies of traditional medicine and its constituent, covering research topics including raw materials, cultivation, phytochemical, pharmacological effects and toxicology, formulation, and biotechnology.

Arjuna Subject : -

Articles 18 Documents

1 2

Search results for , issue "Vol 19, No 2 (2014)" : 18 Documents clear

SUSU KUDA SUMBAWA KHAS INDONESIA BAHAN KOSMETIK ANTIBAKTERI JERAWAT (Staphylococcus epidermidis) Fauzia Nur Laili; Erna Prawita Setyowati; Susi Iravati
Majalah Obat Tradisional Vol 19, No 2 (2014)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Sumbawa horse milk is one of pure milk of wild horses farmed by organic farmers in the island of Sumbawa, West Nusa Tenggara, Indonesia. The communities claim that milk has many benefits. In this study Sumbawa horse milk was effective as an antibacterial against Staphylococcus epidermidis (one of the bacteria caused acne). Antibacterial activity test performed by spread plate method and quantified by standard plate count. Percentage of the number of colonies after contact with Sumbawa horse milk for 5 minutes (used acid control). The result of 25% is 99.96%, 12.5% is 99.99%, 6.25% is 99, 67% and 3.125% is 99.73%. This suggests that Sumbawa horse milk has good antibacterial activity until 3.125%.

UJI AKTIVITAS ANTIANEMIA EKSTRAK ETANOLIK BIJI Parkia speciosa Hassk Shella Nursucihta; Hanifah Ataina Thai’in; Denade Mawlidya Putri; Dwijayanti Ngesthi Utami; Andayana Puspitasari Ghani
Majalah Obat Tradisional Vol 19, No 2 (2014)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Iron deficiency anemia is occurred due to lack of iron within the body, so that the amount of iron for erythropoiesis does not meet the requirement. Petai (Parkia speciosa Hassk) which is widespread in Indonesian archipelago, contain high existence of iron is supposed to be able to increase hemoglobin level in white mouse blood (Rattus norvegicus). The research was carried out by using petai from Wonosari whose made to dry extract by using freezedryer. Petai seed extract (Parkia speciosa Hassk.) injected to Wistar rat (Rattus norvegicus). Data analysis was using One Sample t-Test and ANOVA test in order to find out the effect of the doses towards pharmacological effect. The result showed that petai seed extract (Parkia speciosa Hassk) gave effect towards the enhancement of hemoglobin level (Hb) within white mouse blood (Rattus norvegicus). However, the optimum dosage was not able to be determined yet.

UJI AKTIVITAS REPELAN MINYAK ATSIRI JAHE EMPRIT (Zingiber officinale Roxb. “Cochin Ginger”) DAN JAHE MERAH (Zingiber officinale Roxb. var rubrum) DENGAN BASIS MINYAK WIJEN DAN MINYAK KELAPA TERHADAP NYAMUK Aedes aegypti Sri Mulyani; Reidinda Ratna Puspita Sari; Sitti Rahmah Umniyati
Majalah Obat Tradisional Vol 19, No 2 (2014)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Aedes aegypti is a vector for Dengue. The use of synthetic repellent cause several health issue. Zingiber officinale Roxb. “Cochin Ginger” essential oil (A) and Zingiber officinale Roxb. var rubrum essential oil (B) was used as a repellent for Aedes aegypti. Increasing of repellent activity was strived by formulating A and B with sesame oil and coconut oil as a base. The aim of this study was to compare repellent activity between A and B, to know the influence of oily base to repellent activity of A and B, to know the effective concentration of essential oil in oily base as a repellent.Isolation of essential oil was done by water and steam destilation. Quantitative and qualitative assays by GS-MS. Repellent activity was tested by three steps: initiation, effective consentration assay, and effective concentration of repellent activity. Essential oil on certain concentration (100%, 50% in the base, the effective concentration of SLD) and Lemon grass essential oil was applied on the surface of palm hand. The hand was put into 20x20x20 cm3 cage containing 25 female Aedes aegypti. The number of Aedes aegypti lied on the hand was noted to count protective capacity. First bite was counted as protective time. Analyse was done by One-way ANOVA and Post Hoc Test Tukey HSD (Homogeneous subsets) or Kruskal-Wallis and Mann-Whitney Test. The result showed that A and B contain camphene, mirsene, 1,8-sineol, l-linalool, l-borneol, neral, geraniol, sitral, and α-kurkumen (only A) that quantitatively different. Statistic result showed that B has a greater repellent activity than A. Sesame oil base give a better effect on repellent activity of sesame oil compare than coconut oil. The effective concentration of Zingiber officinale Roxb. “Cochin Ginger” essential oil and Zingiber officinale Roxb. var rubrum essential oil in sesame oil and coconut oil was 75, 85, 85 and 90%, respectively.

PENGARUH PEMBERIAN FRAKSI LARUT AIR EKSTRAK ETANOLIK PISANG KAPAS (Musa paradisiaca L.) TERHADAP KADAR GLUKOSA DARAH SECARA IN VIVO DAN PELACAKAN SENYAWA AKTIFNYA Nunung Yuniarti; Rina Nur Maulawati; Suwijiyo Pramono
Majalah Obat Tradisional Vol 19, No 2 (2014)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Banana is one of Indonesian food which has many pharmacological activities. Pisang kapas (Musa paradisiaca L.), one of Indonesian banana, is well known empirically as laxative, so it can be used in the treatment of constipation. It has been reported that both of chloroformic and ethanolic extract of pisang kapas have antidiabetic activities. However, fractination of those are not yet performed and report about their antidiabetic activities are not yet available. Here we investigated the effect of water-dissolved fraction of ethanolic extract of cotton banana to reduce the blood glucose level in rat model and identified its active ingredient. The oral glucose tolerance method with 60 min glucose loading time was used to induce hyperglicemic condition in rats, either in control group or treatment group. Glibenclamid (positive control), sodium carboxymethyl cellulose (negative control) and the fraction were orally given to the rats in a single dose. To measure blood glucose level photometrically, enzimatic reaction by using diagnostic reagent Glucose GOD FS is applied. Paper chromatography was utilized to identify the ingredient of the fraction qualitatively. The fraction in dose of 0.25 g/kg reduced blood glucose level by 22.28 ± 0.76 %. The fraction contained reductants in addition to glucose, amino acids, and the acids in plants.

ANTIBACTERIAL ACTIVITY TESTING OF N-HEXANE FRACTION OF RED DRAGON (Hylocereus polyrhizus Britton & Rose) FRUIT PEEL ON Staphylococcus aureus ATCC 25923 Sri Amalia; Sri Wahdaningsih; Eka Kartika Untari
Majalah Obat Tradisional Vol 19, No 2 (2014)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Inappropiate antibiotic use was one of the main reason that caused pathogenic microorganism resistance, leads to ineffective treatment. One of those resistance bacteria is Staphylococcus aureus. The research for discovering new antibiotics can help with this issue. The peel of red dragon fruit (Hylocereus polyrhizus) is one of the plants that has antibacterial compounds. The aim of this research is to prove and determine the clear zone value of n-hexane fraction of red dragon fruit’s peel againts Staphylococcus aureus ATCC 2593. The peel was maserated with chloroform, then fractinated by n-hexane. Futhermore, the antibacterial properties of the fraction was tested using Disc Diffusion (Kirby-Bauer) methode with 20 and 40 mg/mL concentrations. Ampicillin used as control positive, and Dymetil sulfoxida (DMSO) used as control negative . Based on the phytochemical screening of the fraction, the n-hexane fraction of the dragon fruit’s peel contain terpenoid and alkaloid. Clear zones produced by 40 mg/mL is 12.80±1,69 mm and for 20 mg/mL is 11.17±1,11 mm.

PENGARUH KOMBINASI EKSTRAK TERPURIFIKASI HERBA SAMBILOTO (Andrographis paniculata (Burm.f.) Nees) DAN HERBA PEGAGAN (Centella asiatica (L.) Urban) TERHADAP TRANSLOKASI PROTEIN GLUT-4 PADA TIKUS DIABETES MELLITUS TIPE 2 RESISTEN INSULIN Novena Yety Lindawati; Agung Endro Nugroho; Suwijiyo Pramono
Majalah Obat Tradisional Vol 19, No 2 (2014)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Sambiloto herb (Andrographis paniculata (Burm. f.) Nees.) and pegagan herb (Centella asiatica (L.) Urban) are excellent medicinal plants which are being developed as traditional for antidiabetic. The research aims to see the effect of combination from purified extract of sambiloto herb and pegagan herb of translocation of GLUT-4 protein in model type 2 diabetes mellitus rats-insulin resistance compared with the use of each purified extract. Test preparations were divided into 8 groups include three from combination purified extract of sambiloto herb and pegagan herb: I (912,1: 300), II (651,5: 500), III (390,9: 700) in mg/kg BW, IV (purified extract of sambiloto herb 1303 mg/kg BW), V (purified extract of pegagan herb 1000 mg/kg BW), VI (positive control metformin 45 mg/kg BW), VII (negative control CMC-Na 0.5%) and VIII (normal control). Parameters measured semi quantitative data translocation of GLUT-4 protein in cells muscles of the thigh (soleus muscle) rats using Immunohistochemistry methods. Test animals are of type 2 diabetes mellitus insulin-resistance was induced by fructose (1,8 g/kg BW) and fat-rich food (95% pellet, 5% egg yolks and 5 mL/ 200 g BW lard) for 70 days. Determination of insulin resistance used 3 parameters such as blood glucose levels, lipid levels (triglycerides, LDL, cholesterol, and HDL), and hypoglikemic tests with glibenklamid compared to normal controls animals. Insulin resistance test results using statistical analysis Independent Samples t-Test showed significant differences (p< 0.05) between normal rats with fat-fructose rats at day-50 and -70. This indicate fat-fructose rats indicated type 2 DM insulin resistance. Group of combination I (combination purified extract of sambiloto herb and pegagan herb (912,1: 300 mg/kg BB) showed effect of translocation of GLUT-4 protein was better than each purified extract with significantly p<0.05 with oneway ANOVA.

UJI AKTIVITAS JAMU GENDONG KUNYIT ASAM (Curcuma domestica Val.; Tamarindus indica L.) SEBAGAI ANTIDIABETES PADA TIKUS YANG DIINDUKSI STREPTOZOTOCIN Mohamad Andrie; Wintari Taurina; Rizqa Ayunda
Majalah Obat Tradisional Vol 19, No 2 (2014)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Diabetes mellitus is a metabolic disorder characterized by hyperglycemia. “Jamu gendong kunyit asam” (Curcuma domestica Val.; Tamarindus indica L.) is a traditional medicine that has antioxidant activity which can contribute to diabetic because of the phenolic content. This aim of this study is to determine the effect of “jamu gendong kunyit asam” on lowering blood glucose levels and repairing damage of the islet cells. 25 male wistar rats (Rattus norvegicus) were divided into five groups. Group I as a normal group without any treatment, group II, III, IV and V were induced with streptozotocin (7mg/ 200gBB) then treated with CMC 1%, glibenclamide (0.27mg / 200gBB), “jamu gendong kunyit asam” 1.90mL/ 200gBB and 3.80mL/ 200gBB. The treatment was done for 28 days. Glucometer was used to measure the gloucose blood level on day 4, 8, 12, 16, 20, 24 and 28. The damages on the islet cells were examined under the microscope on the histology sample of pancreas prepared with Hematoxyllin eosin stain. Datas were analyzed statistically with One Way Anova test, T-Test, and the Kruskal-Wallis test using SPSS 17.0 for Windows. Results showed there is a significant difference (p> 0.05) in blood glucose levels and damage to the islets of Langerhans of the pancreas between the glibenclamide group and treatment of “jamu gendong kunyit asam”. From the research it can be concluded that the “jamu gendong kunyit asam” have antidiabetic activity which is showed by a decrease in blood glucose levels and an improvement of pancreatic islets of Langerhans in streptozotocin-induced diabetic rats with an effective dose of 1.90mL/ 200gBB.

UJI EFEKTIVITAS SEDIAAN GEL MINYAK ATSIRI KULIT BUAH JERUK PONTIANAK (Citrus nobilis Lour. Var. microcarpa) TERHADAP Escherichia coli DAN Staphylococcus aureus Wintari Taurina; Rafikasari Rafikasari
Majalah Obat Tradisional Vol 19, No 2 (2014)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Essential oil is a natural substance that has been known as antibacterial. This research aimed to examine the effectiveness of antiseptic gel from essential oil which taken from rind Pontianak orange. Essential oil from rind Pontianak orange are formulated into a gel and it tested its effectiveness as an antibacterial to Escherichia coli and Staphylococcus aureus. Based on the result of the study, the effective concentration of essential oil to inhibit Escherichia coli is 0,5%, while Staphylococcus aureus is inhibited at concentration 0,1%, 0,3% and 0,5%. The results of the gel test stabilization showed that the homogenity of gel, pH value and stable adhesion are good. Coverage gel increased during 30 days of storage. One Way Anova test analysis showed that the dispersive power of each gel formula does not differ significantly.

Page 2 of 2 | Total Record : 18

1 2

Filter by Year

2014 2014

Filter By Issues

All Issue Vol 30, No 3 (2025) Vol 30, No 2 (2025) Vol 30, No 1 (2025) Vol 29, No 3 (2024) Vol 29, No 2 (2024) Vol 29, No 1 (2024) Vol 28, No 3 (2023) Vol 28, No 2 (2023) Vol 28, No 1 (2023) Vol 27, No 3 (2022) Vol 27, No 2 (2022) Vol 27, No 1 (2022) Vol 26, No 3 (2021) Vol 26, No 2 (2021) Vol 26, No 1 (2021) Vol 25, No 3 (2020) Vol 25, No 2 (2020) Vol 25, No 1 (2020) Vol 24, No 3 (2019) Vol 24, No 2 (2019) Vol 24, No 1 (2019) Vol 23, No 3 (2018) Vol 23, No 2 (2018) Vol 23, No 1 (2018) Vol 22, No 3 (2017) Vol 22, No 2 (2017) Vol 22, No 1 (2017) Vol 21, No 3 (2016) Vol 21, No 2 (2016) Vol 21, No 1 (2016) Vol 20, No 3 (2015) Vol 20, No 3 (2015) Vol 20, No 2 (2015) Vol 20, No 2 (2015) Vol 20, No 1 (2015) Vol 20, No 1 (2015) Vol 19, No 3 (2014) Vol 19, No 3 (2014) Vol 19, No 2 (2014) Vol 19, No 2 (2014) Vol 19, No 1 (2014) Vol 19, No 1 (2014) Vol 18, No 3 (2013) Vol 18, No 3 (2013) Vol 18, No 2 (2013) Vol 18, No 2 (2013) Vol 18, No 1 (2013) Vol 18, No 1 (2013) Vol 17, No 3 (2012) Vol 17, No 3 (2012) Vol 17, No 2 (2012) Vol 17, No 2 (2012) Vol 17, No 1 (2012) Vol 17, No 1 (2012) Vol 16, No 3 (2011) Vol 16, No 3 (2011) Vol 16, No 2 (2011) Vol 16, No 2 (2011) Vol 16, No 1 (2011) Vol 16, No 1 (2011) Vol 15, No 3 (2010) Vol 15, No 3 (2010) Vol 15, No 2 (2010) Vol 15, No 2 (2010) Vol 15, No 1 (2010) Vol 15, No 1 (2010) More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Pudyastuti Kusumaningrum

Contact Email
mot.farmasi@ugm.ac.idm

Phone
-

Journal Mail Official
mot.farmasi@ugm.ac.id

Editorial Address
-

Location
Kab. sleman,

Daerah istimewa yogyakarta

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Pudyastuti Kusumaningrum

Contact Email mot.farmasi@ugm.ac.idm

Phone -

Journal Mail Official mot.farmasi@ugm.ac.id

Editorial Address -

Location Kab. sleman, Daerah istimewa yogyakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Pudyastuti Kusumaningrum

Contact Email
mot.farmasi@ugm.ac.idm

Phone
-

Journal Mail Official
mot.farmasi@ugm.ac.id

Editorial Address
-

Location
Kab. sleman,

Daerah istimewa yogyakarta

INDONESIA