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INDONESIA
INDONESIAN JOURNAL OF PHARMACY
Published by Universitas Gadjah Mada
ISSN : 23389427     EISSN : 23389486     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Indonesian Journal of Pharmacy (ISSN-e: 2338-9486, ISSN-p: 2338-9427), formerly Majalah Farmasi Indonesia (ISSN: 0126-1037). The journal had been established in 1972, and online publication was begun in 2008. Since 2012, the journal has been published in English by Faculty of Pharmacy Universitas Gadjah Mada (UGM) Yogyakarta Indonesia in collaboration with IAI (Ikatan Apoteker Indonesia or Indonesian Pharmacist Association) and only receives manuscripts in English. Indonesian Journal of Pharmacy is Accredited by Directorate General of Higher Education (DGHE) DIKTI No. 58/DIKTI/Kep/2013.
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Articles 1 Documents
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Search results for , issue " Vol 21 No 4, 2010" : 1 Documents clear
The effect of fumaric acid-sodium bicarbonate on the green tea effervescent granule’s quality made by dry granulation Lestari, Agatha Busi susiati; Trisusilawati, Maria Yuli
INDONESIAN JOURNAL OF PHARMACY Vol 21 No 4, 2010
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (592.732 KB) | DOI: 10.14499/indonesianjpharm0iss0pp218-224

Abstract

Tea plant (Camellia  sinensis  L.)  had been  known  to  contains epigallocathecin gallate (EGCG) that can be used to maintain the healthy. In this research, the green tea was  tried to be formulated in effervescent dosage form, with  the  focus  on  the  effect  among  fumaric  acid,  sodium  bicarbonate,  and  the interaction  between  fumaric  acid  and  sodium  bicarbonate  on  the  green  tea extract  effervescent granule’s  physical properties, that made by dry granulation method.  Physical  properties  of  effervescent  granule  that  been  study  were moisture  content,  flow  rate,  disintegration  time,  and  pH  of  the  solution.  The result showed that sodium bicarbonate was dominant in determining pH, granule flow  rate  and  moisture  content  of  granule,  whereas  fumaric  acid  dominant  in disintegration time of effervescent granule.Key words: green tea, fumaric acid, effervescent granule, dry granulation

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