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Berkala Kedokteran
Published by Universitas Lambung Mangkurat
ISSN : 14120550     EISSN : 25485660     DOI : http://dx.doi.org/10.20527
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Berkala Kedokteran is a journal contains scientific articles from original research and literature review in medical and health scope. It is published twice in a year, on February and September.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 15 Documents
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Search results for , issue "Vol 19, No 1 (2023)" : 15 Documents clear
Rice Bran’s Effect on Total Cholesterol, HDL, and LDL/HDL Ratio on Hypercholesterolemia Rats Endin Nokik Stujanna; Sidhi Laksono Purwowiyoto; Wawang Setiawan Sukarya
Berkala Kedokteran Vol 19, No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v19i1.15729

Abstract

Abstract: Hypercholesterolemia is a metabolism disorder characterized by increased or decreased lipid fraction in plasma. The of this research was to prove the effect of Rice bran to decrease of total Cholesterol rate, ratio of LDL / HDL and increase rate of HDL in hypercholesterolemia male white rats (Rattus norvegicus). The Research of the study was pure experiment by using post test randomized control design. Research Sample divided into five groups. The first group as a negative control, the second group as a positive control, and another groups were given rice brand, with various dose: 0,54 ml/a/day, 1,08 ml/a/day, 1,62 ml/a/day. The results of this research is rice brand can decrease of total cholesterol rate ( r2=0,964), decreased of ratio of LDL / HDL (r2=0,836), and increase of rate of HDL (r2=0,951) (ANOVA P=0,000). Rice bran can decrease total cholesterol rate, ratio of LDL / HDL and increase rate of HDL blood.
Berg Balance Scale (BBS) for Early Detection of Fall Risk in the Elderly in the Work Area of Antang Health Center Makassar City Siti Rahmani; Tut Handayani
Berkala Kedokteran Vol 19, No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v19i1.15707

Abstract

Abstract: Falling is one thing that cannot be avoided by everyone, especially the elderly who are affected by a decrease in muscle strength which is one of the factors for falling. The purpose of this study is to early detect the risk of falling in the elderly using the BBS (Berg Balance Scale) questionnaire and find out the age group of the elderly who are prone to experiencing high falling risks. The method used in this study is descriptive research with sampling techniques using purposive. The risk of falling is measured using a BBS (Berg Balance Scale) observation sheet. The results showed that respondents aged 60-74 years with a total of 77 people included in the low fall risk category, there were 64 elderly (83.1%), medium fall risk 12 elderly (15.6%) and respondents with a high risk of falling 1 elderly (1.3%). The conclusion of this study is that as you get older, especially 66 years old and above, the risk of falling will also increase, so it takes awareness of yourself and your family to pay attention to each other to be able to avoid falling.
Total Sleep Deprivation Reduces Quality of Spermatozoa in Male Albino Rat (Rattus norvegicus) Fitranto Arjadi; Sindhu Wisesa; Vitasari Indriani
Berkala Kedokteran Vol 19, No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v19i1.15719

Abstract

Abstract: Sleep deprivation-induced stress decreases the quality of spermatozoa due to the increase of glucocorticoid levels through the hypothalamic-pituitary-adrenal axis. Sleep recovery (SR) restores the effect of stress due to sleep deprivation by decreasing lipid peroxides and other free radicals and increasing glutathione antioxidants. This study aims to determine the spermatozoa quality in male albino rats (Rattus norvegicus) after the stress induction by diverse sleep deprivation protocols. This study is experimental research with posttest-only control group design in 30 male albino rats divided into five groups consisting of group I for negative control (no induction of sleep deprivation), group II for paradoxical sleep deprivation (PSD), group III for total sleep deprivation (TSD), group IV for PSD followed by SR, and group V for TSD followed by SR. PSD and TSD were performed by depriving rats sleep for 20 and 24 hours/day, respectively, for five days. SR was done for the next five days after PSD or TSD. Shapiro-Wilk test was used for normality of data distribution, and Levene's test was used for variance homogeneity. Comparative hypothesis was then analyzed with One Way Analysis of Variance (ANOVA) test, and significance between groups was analyzed with Tukey's Post-Hoc test. Group III (TSD) demonstrated the lowest mean of spermatozoa count (41,53±2,29), spermatozoa morphology (13,00±2,91), spermatozoa viability (31,00±7,39), and percentage of motility rate (37±8,58%) among all groups. In conclusion, total sleep deprivation (TSD) decreases the quality of spermatozoa in male albino rats (Rattus norvegicus).
Total Flavonoids Determination and Antioxidant Activity of Ethyl Acetate, Ethanol, and Methanol Extracts from Seluang Belum Root (Luvunga sarmentosa (Blume) Kurz.) Nashrul Wathan; Muhammad Ikhwan Rizki; Amalia Khairunnisa; Hilneser Simamora
Berkala Kedokteran Vol 19, No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v19i1.15733

Abstract

Abstract: Flavonoids are phenolic compounds from nature that found in almost all parts of the plants. Seluang belum (Luvunga sarmentosa (Blume) Kurz.) root is one of the medicinal plants used by Dayak people in Central and South Kalimantan where in previous studies its part was contains flavonoids. This study aims to evaluate the best solvent for extracting flavonoid content and antioxidant activity using ethanol, methanol and ethyl acetate. The antioxidant activity performed by in vitro technique by DPPH assay. Total flavonoids content on the extracts of L. sarmentosa root determined using UV-Vis spectrophotometric with aluminium chloride method and calculated as quercetin equivalents (QE). The results showed the highest antioxidant activities confirmed for the methanol extract (IC50 = 80.33 ppm). The highest of total flavonoids contents was recorded for the ethanol extract (6.56 ± 0.006% w/w Quercetin Equivalent). The results showed that treatment effect of different solvent extraction was significant (sig <0.05) on total flavonoid and antioxidant activities from L. sarmentosa root.
Effectiveness of Dexamethasone, Methylprednisolone and Hydrocortisone Administration on LDH, CRP, D-and PaO2/FiO2 Ratio Muhammad Zubaidi; Mohamad Isa; Ira Nurrasyidah
Berkala Kedokteran Vol 19, No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v19i1.15708

Abstract

Abstract: Steroids are the standard recommended therapy for COVID-19, especially in critically ill patients. Previous studies have shown that steroids are beneficial for inflammatory markers such as C-Reactive Protein (CRP), Lactate Dehydrogenase (LDH) and D-dimer as well as the value of the PaO2/FiO2 ratio. This study aims to determine the differences in the effects of the steroid’s dexamethasone, methylprednisolone and hydrocortisone on inflammatory markers. This research is a retrospective cohort study. The samples were all COVID-19 patients with critical degrees from January to June 2021. The independent variables were dexamethasone, methylprednisolone and hydrocortisone. The dependent variables are CRP, LDH, D-dimer and the ratio of PaO2/FiO2. The statistical test used was the Kolmogorov-Smirnov test and continued with the Kruskal-Wallis test and the Mann-Whitney U test. A total of 148 subjects with a total sample of dexamethasone 60, methylprednisolone 55 and hydrocortisone 33. The statistical test results showed a significant difference in the effect of the steroid dexamethasone, methylprednisolone and hydrocortisone on the value of the PaO2/FiO2 ratio (p=0.04). Administration of hydrocortisone and dexamethasone was statistically superior to methylprednisolone for increasing the PaO2/FiO2 ratio.

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