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INDONESIA
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)
Published by Universitas Sriwijaya
ISSN : 25409395     EISSN : 25409409     DOI : -
Core Subject : Science, Social,
Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science
Indonesian Journal of Fundamental and Applied Chemistry (IJFAC) is an international research journal and invites contributions of original research articles as well as review articles in several areas of chemistry. The journal aims to publish refereed, high-quality research papers with significant novelty and short communications in all branches of chemistry. Papers which describe novel theory and its application to practice are welcome, as are those which illustrate the transfer of techniques from other disciplines. IJFAC calls for papers that cover the following fields: Biochemistry Inorganic chemistry Physical chemistry Organic chemistry Analytical chemistry Applied Chemistry All papers are peer reviewed by at least two referees. Papers presented at conferences are peer reviewed and selected with the same standards as individually submitted papers. They therefore have the same archival value. Article should be submitted by the Online Submission Module at www.ijfac.unsri.ac.id or email to ijfac@unsri.ac.id
Arjuna Subject : -
Articles 8 Documents
 1 
Search results for , issue "Vol 10, No 1 (2025): February 2025" : 8 Documents clear
Antibacterial activity of deodorant stick formula from ethyl acetate fraction of beluntas leaves (Pluchea indica L.) against Pseudomonas aeruginosa and Streptococcus pyogenes bacteria that cause body odor. Adriana, Yulis; Fauziah, Siva
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 10, No 1 (2025): February 2025
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

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Abstract

Beluntas contains flavonoids, tannins and steroids which can inhibit growth and reduce the risk of infection by microorganisms. Empirically, beluntas leaves are used by people to overcome unpleasant body odor, usually body odor is caused by the Pseudomonas aeruginosa and Streptococcus pyogenes. Stick deodorant is a cosmetic made from; sodium stearate (steric acid and sodium hydroxide) and as a solvent using propylene glycol. The aim of this research was to formulate the ethyl acetate fraction of beluntas leaves into a stick deodorant and test the antibacterial activity of Pseudomonas aeruginosa and Streptococcus pyogenes using the well diffusion method and test physical, chemical and quality parameters. microbiology. Stick deodorant were made into three formulations with different concentrations of the ethyl acetate fraction of beluntas leaves, namely Formula I with a concentration of 20%, Formula II is 30% and Formula III is 40% with the harding agent stearic acid: NaoH 10% (8.5:7.5). The quality test of the three formulation sticks deodorants met the requirements for pH test (range 6-7.0), homogeneity test, melting point test (range 55.40-60.9 °C), Microbiology test and water capacity test (aw). The results of the inhibition test against Streptococcus pyogenes were between 23.33-8.33 mm in the very strong inhibition category, the comparison deodorant had no inhibitory area and gentamycin 0.01% as a positive control had an inhibitory area of 29.66 mm in the very strong category. The inhibitory power against Pseudomonas aeruginosa is 11.5-18.92 mm in the strong inhibitory category, the comparison deodorant has no inhibitory area and 0.01% gentamycin as a positive control has inhibitory area of 21.66 mm in the very strong category.Keywords: Ethyl acetate fraction, stick deodorant, Pluchea indica.L, Pseudomonas aeruginosa, Streptococcus pyogenes, inhibition test
Thermal and Kinetic Study of Fine Coal And Palm Kernel Shell Gasification Using TGA Analysis Dwipayana, Hendra; Faizal, Muhammad; Said, Muhammad; Hasanudin, Hasanudin
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 10, No 1 (2025): February 2025
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v10.i1.49

Abstract

Indonesia is rich in natural resources, including coal and palm kernel shells (PKS), which can be used in the gasification process. This study compares the gasification potential of palm kernel shells and fine coal, focusing on their thermal properties and activation energy. Thermogravimetric Analysis (TGA) shows that PKS have higher volatile matter (67.25%) and lower fixed carbon (20.90%) than fine coal (33.53% volatile matter, 32.98% fixed carbon). at 450 °C, PKS lose 11% of their mass in one hour and reach a 78% loss by the end of the process, while fine coal loses 70% after more than 200 minutes. The activation energy for PKS is lower (38.925 J/mol) than fine coal (41.012 J/mol). In gasification, palm kernel shells produce more hydrogen (26% mol) and less carbon dioxide (11% mol) than fine coal, which produces more methane (28% mol) and carbon dioxide (22% mol). These results suggest that PKS are a more efficient and eco-friendly option for gasification.Keywords: Fine coal, palm kernel shells, activation energy, thermogravimetric analysis (TGA), gasification
Harnessing Electrochemical Processes for Enhanced Struvite Crystallization: A Comprehensive Review Ariyanto, Eko; Yusmartini, Eka Sri; Gusmiatun, Gusmiatun; Fatimah, Fatimah; Purwoko, Mitayani
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 10, No 1 (2025): February 2025
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

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Abstract

The recovery of nutrients from contaminated water and wastewater can effectively mitigate both the nutrient burden on water resources and the associated environmental issues affecting aquatic ecosystems. This approach presents a valuable solution towards achieving environmental and societal sustainability. Consequently, struvite crystallization technology has emerged as a promising method for nutrient recovery, as the resulting precipitate can be recycled as a natural fertilizer. This review aims to elucidate the characteristics of struvite and provide insight into the fundamental process of crystallization. Furthermore, it comprehensively discusses the various variables that influence struvite crystallization, with a special focus on its application in urine-contaminated water using electrochemical methods. The review also highlights the advantageous on environmental and economic aspects. In addition, the limitations of struvite crystallization technology are examined, and future research prospects are explored, particularly in the context of electrochemical techniques which offer innovative solutions for controlled nutrient extraction. Ultimately, this work serves as a foundational resource for the future utilization of struvite crystallization technology in nutrient recovery, in response to the escalating environmental challenges and depletion of natural resources.Keywords: Struvite formation, electrochemical process, magnesium anode, struvite crystallization, natural fertilizer
Antibacterial and Antibiofilm Activity Testing of Black Betel Leaves (Piper betle L. var. nigra) Ethanol Extract on Staphylococcus aureus and Pseudomonas aeruginosa Using Microdilution Method Adha, Tasya Hardina; Ikawati, Zullies; Pratiwi, Sylvia Utami Tunjung
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 10, No 1 (2025): February 2025
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v10.i1.59

Abstract

The use of antibiotics is key to treating infected wounds. However, its effectiveness has begun to decrease due to the high bacterial resistance, which is caused by the phenomenon of biofilm. Therefore, it’s necessary to discover new antibacterial and antibiofilm activity agents that can be used as alternative therapies. This study aims to test the antibacterial and antibiofilm activity of black betel leaves (Piper betle L. var. nigra) ethanol extract. Antibacterial and antibiofilm activity test was conducted using the microdilution method against Staphylococcus aureus and Pseudomonas aeruginosa with concentration variations 4; 2; 1; 0.5; 0.25; and 0.125 mg/mL, also used positive control kanamycin 10 mg/mL and negative control DMSO 1%. The results showed that the black betel leaves ethanol extract had low antibacterial activity with MIC50 > 4 mg/mL for both bacteria and vigorous antibiofilm activity with MBIC50 < 0.125 mg/mL for S. aureus and MBIC = 0.491 mg/mL for P. aeruginosa. The antibacterial activity of the black betel leaves ethanol extract was lower than it’s antibiofilm activity, the antibacterial and antibiofilm activities of the black betel leaves ethanol extract were higher against S. aureus than P. aeruginosa.Keywords: Antibacterial, Antibiofilm, Piper betle L. var. nigra
Comparison of Alum and Coal-Based Activated Carbon for the Treatment of Raw Water Subroto, Subroto; Said, Muhammad; Ibrahim, Eddy; Hariani, Poedji Loekitowati
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 10, No 1 (2025): February 2025
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v10.i1.23

Abstract

The availability of clean water is an essential element for supporting the life cycle and sustainable development. The efficiency of providing raw water sources is an important factor for adequate water quantity and quality. This study examines the effectiveness of alum compared with coal-based activated carbon in the removal of Fe, Mn, and turbidity in raw water from the Lematang River, Muara Enim Regency. Activated carbon in this study was produced using a KOH activator with varying activation temperatures (700 °C, 800 °C, and 900 °C). The research results showed that the quality of the third activated carbon met the active carbon quality standards (moisture, ash content, Methylene blue dye and iodine adsorption capacity), but the activated carbon with activation at a temperature of 800 °C had the largest surface area. Activated carbon was proven more effective in reducing Fe and Mn concentrations than alum, while alum was superior in reducing turbidity. After three cycles of activated carbon regeneration, the reduction in Fe and Mn remained below 5%. These results show that activated carbon is a cost-effective and eco-friendly option for raw water treatment.Keywords: Coal, activated carbon, alum, raw water, regeneration
Study of Mangan Peroxidase (Mnp) Enzymes from Pleurotus Ostreatus Produced using Coffee Grounds and Rice Bran as Substrates through Response Surface Methodology Jannah, Mifthahul; Hermansyah, Hermansyah; Hariani, Poedji Loekitowati
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 10, No 1 (2025): February 2025
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v10.i1.68

Abstract

This study aimed to optimize the production of Manganese Peroxidase (MnP) enzyme from Pleurotus ostreatus using agricultural waste substrates such as coffee grounds (CG) and rice bran (RB) through Response Surface Methodology (RSM) approach. Optimization was conducted using a Central Composite Design (CCD) with three main variables, namely MnSO₄ concentration (0.5-1.5) mM, incubation temperature (25-35) °C, and reaction time (20-30) min. The enzyme fractionation process was carried out by ammonium sulfate saturation (0-20%), (20-40%), (40-60%), followed by dialysis, and SDS-PAGE analysis. The results showed that the 0-20% fraction of CG:RB (50:50) substrate had the highest enzyme activity, which was 20.588 ± 0.141 U/mL, with the highest specific activity of 76.967 ± 0.325 U/mg. The highest protein content was found in CG:RB (0:100) substrate at 0.825 ± 0.016 mg/mL. However, the enzyme activity was lower due to the presence of non-enzymatic proteins and natural inhibitors. This study successfully demonstrated that the substrate combination of CG:RB (50:50) provided optimal results for MnP production. The Response Surface Methodology proved effective in optimizing process variables, providing great potential for biotechnology applications using agricultural waste as an environmentally friendly raw material.Keywords: Pleurotus ostreatus, Manganese Peroxidase, Coffee Dregs, Rice Bran, RSM, SDS-PAGE
The Effect of Oxidative Stress on Growth and Antioxidant Activity of Microalgae Oocystis sp Musifa, Eva; Warni, Mega; Talib, Ramanisa Muliani; Dharma, Abdi; Mardiah, Elida; Harvianti, Yuniar; Indah, Indah; Tania, Alinda
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 10, No 1 (2025): February 2025
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v10.i1.30

Abstract

This study was conducted to see the effect of growth and antioxidant activity of microalgae Oocystis sp before and after adding NaOCl to Growmore medium combined with urea. Antioxidant activity test was conducted by calculating IC50 spectrophotometrically with the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. Oocystis sp extract was obtained by sonication and maceration process with methanol solvent. The results showed the best growth curve for the growth of microalgae Oocystis sp in a mixture of Growmore medium 0.02% b/v and Urea 0.002% b/v. These results also showed a decrease in Oocystis sp growth in a mixture of Growmore medium 0.02% b/v and Urea 0.002% b/v with the lowest growth decrease in the addition of NaOCl with a concentration of 0.01%. The IC50 value of Oocystis sp extract in methanol solvent has high antioxidant activity in Growmore 0.02% b/v + Urea 0.002% b/v medium, which is 55.5862 mg/L. It can be concluded that NaOCl affects the growth and antioxidant activity of microalgae Oocystis sp, but at certain concentrations NaOCl experienced a negative effect.Keywords: Microalgae, Oocytis sp, Oxidative Stress, Growth, Antioxidant
Thermogravimetric Analysis of EFB and Palm Shells as Gasification Fuels: Kinetic and Activation Energy Study Komala, Ria; Rohendi, Dedi; Gulo, Fakhili; Faizal, Muhammad
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 10, No 1 (2025): February 2025
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v10.i1.37

Abstract

Solid waste from palm oil industry such as EFB and palm kernel shells pose environmental challenges if not properly managed. This study investigated the thermal characteristics and decomposition kinetics of EFB and palm kernel shells through proximate analysis and thermogravimetric analysis (TGA). The results indicate that palm kernel shells have a greater fixed carbon content (21.03–21.35%) than does EFB (19.60–20.06%), whereas EFB has a greater ash content (4.74–5.38%) than does palm kernel shells (1.25–1.31%). EFB showed a weight loss of 94.67% after 233.33 minutes of heating, whereas it was 99% for the palm kernel shells. The peak temperatures reached were 936.67 °C for the EFB and 930 °C for the palm kernel shells. At 600°C, EFB produced more syngas than palm kernel shells did. The calculated activation energies were 4482.19 J/mol for EFB and 4484.97 J/mol for palm kernel shells. This research enhances the understanding of the gasification efficiency of these materials, aiding in the optimization of eco-friendly energy production.Keywords: Empty fruit bunches, palm kernel shells, activation energy, thermogravimetric analysis, gasification

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