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MNJ (Malang Neurology Journal)
Published by Universitas Brawijaya
ISSN : 24076724     EISSN : 24425001     DOI : -
Core Subject : Science,
Neuroscience
Malang Neurology Journal is a peer-reviewed and open access journal that focuses on promoting neurological sciences generated from basic neurosciences and clinical neurology. This journal publishes original articles, reviews, and also interesting case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures of neurology disease, treatment, or other health issues related to neurology that is important also acceptable. Letters and commentaries of our published articles are welcome.
Arjuna Subject : -
Articles 20 Documents
 1   2 
Search results for , issue "Vol. 10 No. 1 (2024): January" : 20 Documents clear
A GLOBAL SCIENTOMETRIC ANALYSIS OF HERPES ENCEPHALITIS RESEARCH IN THE LAST 50 YEARS Yildirim, İrem; Alkan, Sevil
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.12

Abstract

Background: Herpes encephalitis is the most common of all encephalitis worldwide and has the highest mortality rate. The aim of this study is to review articles on this topic in order to provide a guide for future herpes encephalitis studies to assess current publishing trends and hotspots on herpes encephalitis research globally. Objective: People have been affected by the herpes virus for many years, but advances in supportive care and antiviral drugs have only recently made it possible for doctors to treat the most severe types of infections. To the authors' knowledge, however, no bibliometric analysis has been done to rate Herpes encephalitis research. In order to enhance research in this area, this study used a bibliometric analysis to assess current publishing trends and hotspots on herpes encephalitis research globally. Methods: The Web of Science database was searched for pertinent publications between January 1970 and December 2021. The research points, comprising publishing countries, affiliations, first authors, cited authors, cited references, and their clustering, as well as keyword co-occurence, were analyzed using VosViewer to identify  research trends and hotspots. Results: The results of this study's search methodology revealed that between 1970 and 2021, 2138 documents. Only articles (n=1223) were included the study.  89.37% of the articles were written in English. The first article published in 1970 and  most of the articles published in the years 1982, 1988, 2007, 2016, and 2017. The United States of America (USA) (29.109%), England (9.076%), France (7.441%), Japan (7.359%) and Germany (7.032) were the other top ranked countries. The most citation numbers were recorded in the year 2021. Conclusion: This bibliometric analysis outlined the general overview for Herpes encephalitis research and offered insightful guidance for continuing investigations.
A RARE CAUSE OF ENCEPHALOPATHY IN CHILDREN: PRES SYNDROME Tosun, Demet; Akçay, Nihal; Oğur, Mustafa; Şevketoplu, Esra
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.16

Abstract

Background: Major clinical symptoms of posterior reversible encephalopathy syndrome include headache, mental status changes, visual disturbances, seizures, especially in the posterior cerebral region, and radiographic findings of vasogenic edema, especially in the posterior cerebellar region. Case Report: We present our 6-year-old patient with chronic renal failure. admitted to our pediatric emergency department with an acute hypertensive crisis. Generalized tonic-clonic seizures and mental status changes were accompanied in the follow-up of the patient whose GCS was 11; With symptomatic treatment, regression in both clinical complaints and imaging findings of our patient is consistent with Posterior reversible encephalopathy syndrome (PRES). Conclusion: It is imperative to consider PRES syndrome as a differential diagnosis when pediatric patients exhibit symptoms of acute encephalopathy. It is crucial to emphasize the critical nature of early diagnosis and treatment, as well as the potential for complete recovery without sequelae.
WEB OF SCIENCE BASED BIBLIOMETRIC ANALYSIS STUDY: TUBERCULOSIS MENINGITIS FROM 1970 TILL TO PRESENT Alkan, Sevil; Celik, Mehmet; Gürbüz, Esra
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.4

Abstract

Background: Tuberculous meningitis (TBM) is the most dangerous and incapacitating type of tuberculous and has a high mortality rate. Objective: We aimed to reveal the general perspective of tuberculous meningitis, with bibliometric analysis. Methods: This study included only articles as a document type, searched in the Web of Science database, indexed in ‘‘Science Citation Index Expanded’’ and ‘‘Emerging Sources Citation Index’’ from 1970 to the present. Results: A total of 2370 publications were reached and 1516 articles were included in the study. 87.401% of them were published in Science Citation Index Expanded and 12.599% in  the Emerging Sources Citation Index. The articles were mostly published in English (92.084%) language. Most of the articles (6.266%) were published in 2021. 107 countries contributed to the tuberculous meningitis literature. India, the USA, and South Africa were the countries with the highest number of articles published. Most articles were published in “The International Journal of Tuberculosis and Lung Disease’’ journal. The countries that financially supported tuberculous meningitis studies the most were the USA and the United Kingdom (UK). Conclusion: TB continues to be an important public health problem globally, especially in low-middle-income countries. In this study, it was observed that there has been a significant increase in publications related to TBM in recent years. It was seen that the USA and UK were the countries that provided the most publications and financial support to the studies, although they were not, particularly the countries where TBM was watched most frequently.
PROFILE OF CHARACTERISTIC, RISK FACTOR, AND CLINICAL SEVERITY OF ISCHEMIC STROKE PATIENTS Perdana, Philips Carel; Ardhi, Mohammad Saiful; Susanto, Hermawan
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.8

Abstract

Background: Ischemic strokes account for 87% of all strokes, making them the second leading cause of disability and one of the leading causes of mortality worldwide. Using the National Institutes of Health Stroke Scale (NIHSS), the clinical severity of an ischemic stroke can be assessed. Objective: The objective of this study is to ascertain the clinical severity, risk factors, and characteristics of patients with ischemic stroke at the neurology department of RSUD Dr. Soetomo Surabaya. Methods: The participants in this descriptive observational study comprise individuals who sought medical attention at the neurology department of RSUD Dr. Soetomo between January 2019 and December 2020 due to an ischemic stroke. The observed profile comprises the following factors: age, gender, obesity, smoking status, alcohol consumption, physical inactivity, family history of vascular disease, form of infarction, dyslipidemia, hypertension, cholesterol, and diabetes. Results: In the medical record data collection of 89 ischemic stroke patients, 36 patients were excluded when they first entered the hospital. So a total of 53 ischemic stroke patients were collected. 29 (54.72%) patients are male. The age range is dominated by 48 - 62 years from 29 (54.72%) patients. 44 (83.02%) patients are Javanese. 18 (33.96%) patients had a history of smoking, 1 (1.89%) patient consumed alcohol, and 1 (1.89%) patients were inactive physically. 13 (24.53%) patients have a family history of vascular disease, 45 (84.91%) patients have hypertension, 26 (49.06%) patients have dyslipidemia, and 19 (35.85%) patients have diabetes. 34 (64.15%) patients had moderate strokes, 15 (28.30%) patients had mild strokes, 2 (3.77%) patients had moderate-severe strokes, and 2 (3.77%) patients had severe strokes according to the results of the NIHSS assessment on the first admission. Conclusion: Ischemic stroke patients were mostly in the age range of 48 – 62 years. Comorbidities such as hypertension, dyslipidemia, hypertriglyceridemia, and diabetes are present in the majority of patients. The NIHSS scoring identified moderate stroke patients as having the most frequent outcomes, followed by patients with mild stroke.
ANGIOPLASTIC STENOSIS IN SPONTANEOUS BILATERAL CAROTIC ARTERY DISSECTION: A CASE REPORT Subandi, Subandi; Danuaji, Rivan; Suroto, Suroto; Mirawati, Diah Kurnia; Budianto, Pepi; Hambarsari, Yetty; Hamidi, Baarid Luqman; Prabaningtyas, Hanindia Riani; Hutabarat, Ervina Arta Jayanti; Ristinawati, Ira; Tejomukti, Teddy; Tedjo, Raden Andi Ario; Santosa, Novian Anindito; Putra, Stefanus Erdana; Hafizhan, Muhammad
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.20

Abstract

Case: A 28-years-old woman presented with sudden right extremities weakness, right sided facial droop, and not being able to speak. On examination, the patient had upper motor neuron (UMN) hemiplegia and motor aphasia. On blood laboratory, we found D-dimer level of 1068 ng/dl. A non-contrast head CT-scan and CT-angiography showed left cerebral hemisphere infarction, and bilateral carotid artery stenosis. Further investigation with transcranial Doppler demonstrated partial stenosis of internal carotid artery (ICA). On cerebral digital subtraction angiography (DSA), we observed pseudoaneurysm on the right ICA and flame-shaped appearance on the left ICA, both are common radiological finding of ICA dissection. Then we performed stenting angioplasty on bilateral ICA to provide recanalization, and aspirin 80mg q.d. and clopidogrel 75mg q.d. was initiated. Conclusion: Spontaneous dissection of the carotid artery can occur on young adults. DSA is considered as the gold standard for vascular examination, and stenting with angioplasty was performed for recanalization to prevent the progression to severe stroke.
MAGNETIC RESONANCE IMAGING FINDINGS IN SEIZURE PATIENTS WITH NORMAL NEUROLOGICAL EXAMINATION Ardalani, Ghasem Fatahzadeh; Anari, Hasan; Sadegiyeh-Ahari, Saeed; Rezvanipour, Hossein
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.5

Abstract

Background: Imaging plays a critical role in the treatment and diagnosis of individuals experiencing seizures, particularly those whose seizures cannot be explained. In various circumstances, CT scans and MRIs (Magnetic Resonance Imaging) are utilized in tandem. Objective: The purpose of this research was to evaluate the MRI findings of patients referred to Alavi Hospital with seizures and a normal neurological examination. Methods: This case-series study examined one hundred patients with epilepsy who underwent normal neurological examinations. All patients' imaging reports were meticulously examined, and any changes were documented in pre-established checklists that comprised of the following: age, gender, family history, EEG (electroencephalogram) results, neurological assessments (including motor, plantar, and tendon reflexes), and MRI findings derived from the patients' files and clinical histories. Result: In the range of 11 to 58 years, the mean age of patients was 7.46 + 32.62 years. Males comprised forty-six (46%) of the patients. In45% of the cases, a familial history of seizures was documented (n=45). Normal EEG results were obtained in 62 cases (62%). Twenty cases (20%) of abnormalities were detected on MRI, seven of which were tumor lesions, as reported by the radiologist. The imaging of the patient's brain revealed no significant correlation between the pathological findings and variables such as age, gender, or family history. No significant correlation was observed between electroencephalogram results and pathological findings on brain imaging in patients with epilepsy. Conclusion: brain imaging partially compensates for the false negatives that occur during electroencephalograms, and concurrently employing both modalities enhances the ability to diagnose underlying issues in patients experiencing seizures.
EVALUATION OF THE OPTIC NERVE IN MIGRAINE PATIENTS BY MAGNETIC RESONANCE IMAGING HISTOGRAM ANALYSIS Kara, Turgay; Dogan, Adil; Baykara, Murat; Yıldız, Cemile Buket Tugan; Tural, Ibrahim Cagri
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.6

Abstract

Background: Migraine is a chronic, paroxysmal neurovascular primary headache disease seen in approximately 15% of the world. In many studies on migraine, changes in the gray and white matter at the microvascular level have been detected. 90% of patients with aura have visual auras. Histogram analysis is an artificial intelligence application that can detect microscopic pathology in tissues before visual pathology. Objective: Histogram analysis was utilized in our investigation to ascertain whether or not the optic nerve, which is ordinarily visible on magnetic resonance images, was impacted. Methods: 120 adult migraine patients and 120 control group were involved. MRI was performed on a Philips 1.5 Tesla Ingenia device. For histogram analysis, optic nerve region of interest (ROI) measurement was performed in the coronal planes from the edges of the intraorbital segment, whose borders can be clearly distinguished, by using the manual drawing tool for both eyes. The data were analyzed through the MatLab program. Results: The average age of individuals diagnosed with migraine was 37.04 ± 9.57 years, whereas the control group had an average age of 37.8 ± 10.8 years. Between the two groups, 27 distinct parameters computed via histogram analysis were compared. In the control and migraine groups, no statistically significant distinction was observed between the right and left eyes. In contrast to the migraine and control groups, the Mean Local Standard Deviation of the Matrix was found to be The histogram's 5th, 10th, 25th, and 75th percentiles, the average squared, the root sum of squared, the size percent M, the most frequently used value, the median, and the average are all quantified using the root sum of squares. The number of pixels is also indicated. It was determined that ROI values were statistically significant (p0.05). Conclusion: In migraine patients, alterations in the optic nerve, which are typically discernible on conventional magnetic resonance images, may be identified via histogram analysis.
THE EFFECT OF HIGH-INTENSITY FOCUSED ELECTRO-MAGNETIC (HIFEM) THERAPY ON URINARY INCONTINENCE Daryanto, Besut; Kustono, Andri; Negara, Edvin Prawira
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.9

Abstract

Introduction: Urinary incontinence (UI) is an involuntary leakage of urine, regardless of the amount or frequency, which alters physical, emotional, and social well-being and quality of life. The therapy currently being studied is magnetic stimulation (MS) has been used to stimulate the pelvic floor muscles. It is based on Faraday's law of magnetic induction, where a changing magnetic field over time induces electrical activity that depolarizes nerves and causes contraction of the pelvic floor muscles. However, the research on the effect of High-Intensity Focused Electromagnetic is still minimal, especially in Indonesia, so its effectiveness in overcoming UI in Indonesia is still doubtful. Method: This study used a prospective cohort design where patients were followed for one month. Patients were followed from when they were first diagnosed until the therapy was completed and evaluated. The variables in this study were as follows: pre and post International Prostate Symptom Score (IPSS), Overactive Bladder Syndrome Score (OABSS), Barhal index, and progress of patient complaints from the first therapy. Result: This research was conducted for 6 sessions, and significant results were obtained in sessions 1, 4, 5, and 6. From this data, we conclude that the HIFEM therapy had a significant effect from session 4. Furthermore, we found a significant therapeutic effect between sessions 4 and 6, but not between sessions 4 and 5. There was also a significant therapeutic effect between sessions 5 and 6. Conclusion: HIFEM can improve incontinence and OAB complaints. HIFEM works to strengthen the pelvic floor muscles.
THYMOMA REMISSION WITH STEROID THERAPY IN MYASTHENIA GRAVES WITH GIANT THYMOMA Şimşek, Fatma
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.17

Abstract

The thymoma is an uncommon neoplasm. It is detected incidentally in some patients. Myasthenia gravis (MG) is an autoimmune disease and closely related to thymoma. Between 10% and 20% of patients with MG have thymoma and 30%–50% of patients with thymoma have MG. Thymectomy is part of the treatment for MG patients. However, the patient must be stabilized before thymectomy. We present a 26-year-old male case with giant thymoma. In the initial evaluation of the patient, a giant-sized thymoma was observed, which was thought to cause vascular invasion.  Interestingly, the introduction of corticosteroid therapy for MG symptom management resulted in unexpected significant remission of giant thymoma. After steroid treatment, thymectomy was performed. This case demonstrated that steroid therapy was effective and well tolerated for the treatment of both thymoma and MG. Therefore, steroid therapy should be continued for a while for thymoma remission before surgery in MG patients with giant thymoma. Treatment is arranged according to the clinical findings of the patient. Each patient's response to treatment and duration of treatment may differ from each other.   After thymectomy, long-term follow-up is required for the possibility of thymoma becoming malignant.
THE CORRELATION BETWEEN NEUTROPHYL-LYMPHOCYTE RATIO AND OPTIC NERVE FUNCTION IN METABOLIC SYNDROME PATIENTS Prayitnaningsih, Seskoati; Puspasari, Eka Fajarina; Hamid, Aulia Abdul; Rosandi, Rulli
MNJ (Malang Neurology Journal) Vol. 10 No. 1 (2024): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2024.010.01.10

Abstract

Background: The neutrophil lymphocyte ratio (NLR) is a new biomarker in predicting various cardiovascular disorders and was expected to be a biomarker for Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) in metabolic syndrome (MetS) patients. Objective: This study aims to determine the correlation between NLR and optic nerve function in MetS patients. Methods: A cross sectional study involving 42 patients divided into 3 groups, consist of control group(14 patients, 28 eyes), MetS without NAION group(14 patients, 28 eyes) and MetS with NAION group(14 patients, 19 eyes). The study was conducted at Saiful Anwar General Hospital on January-March 2019. Optic nerve function evaluation includes visual acuity (VA) from Snellen chart, Retinal Nerve Fiber Layer(RNFL) from OCT, contrast sensitivity from Pelli Robson test, and visual field defect from Humphrey's perimetry. NLR was calculated and compared among groups using anova test. Then the correlation between NLR and optic nerve function was investigated using Pearson and Spearman test. Results: The NLR was significantly different among groups (p= 0.009), mean of control, MetS without NAION, and MetS with NAION groups 1.70, 1.86, and 2.40 respectively. There were signifficant negative correlation between NLR and visual field defect (p= 0.001,r= -0.487), contrast sensitivity (p= 0.015,r= -0.372), and VA (p= 0.041,r= -0.316), whereas positive correlation between NLR and RNFL statistically insignificant (p= 0.171, r = 0.215). Conclusion: There were signifficant negative correlation between NLR and visual field defect, contrast sensitivity, VA, whereas positive correlation between NLR and RNFL statistically insignificant. NLR is expected to be a potential biomarker for screening NAION in MetS patients.

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