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All Journal Smart Medical Journal Indonesian Journal of Medicine
Probowirasmi, Prasasti
Unknown Affiliation
Health Professions Medicine & Pharmacology Public Health

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Early vs. Late Initiation of Hemodialysis: Early Initiation as a Life-Saving Option in Stage III Leptospirosis Induced Acute Kidney Injury Probowirasmi, Prasasti; Arifin; Aliyah Roselyn, Nadiya; Helmi Fakhruddin
Indonesian Journal of Medicine Vol.11 No.1 (2026)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2026.11.1.892

Abstract

Background: Leptospirosis is a zoonotic disease endemic in tropical regions with a high burden among low-income populations. Its clinical spectrum ranges from mild illness to severe Weil’s disease, which may involve multiple organs with common and severe complication is acute kidney injury (AKI) with no specific therapy exists. In this report, we describe how early hemodialysis may improve outcomes. Case Presentation: A 60-year-old man presented with a 10-day history of fever. He also reported calf pain and jaundice that had appeared one week prior to admission. Over the past week, the patient experienced decreased urinary frequency, with urine becoming more concentrated in color. Laboratory tests revealed thrombocytopenia, leukocytosis, elevated SGOT and SGPT levels, hyperbilirubinemia, and azotemia. Leptospira IgM was positive. Urinalysis demonstrated proteinuria and bilirubinuria. The patient’s Modified Faine’s Criteria score was 34, and his SOFA score was 11. Results: Patient was diagnosed with Weil's disease with AKI III complicated by sepsis. The furosemide stress test was administered to the patient but the results was not favorable therefore hemodialysis was initiated leading to an improvement in the patient’s condition. Conclusion: Early initiation of hemodialysis in patients with leptospirosis induced AKI provides favorable immediate outcome and prevents them from falling into uremic syndrome leading to mortality.
Correlation Between HbA1c Levels and Chronic Complications in Patients with Type 2 Diabetes Mellitus at UNS Hospital Probowirasmi, Prasasti; Sukmagautama, Coana; Munawaroh, Siti
Smart Medical Journal Vol 8, No 1 (2025): April
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v8i1.94924

Abstract

Introduction: Diabetes mellitus has been a burden for global health with 422 million patients. Complication in diabetes patients increase the cost of patient care. This research was conducted to determine the correlation between HbA1c levels and chronic complications of type 2 diabetes mellitus in UNS hospital. Furthermore, the HbA1c predictive threshold and the incidence of chronic problems linked to type 2 diabetes mellitus are also explained in this paper.Methods: This study used a retrospective cross-sectional design based on 133 inpatient medical records from 2022. Data were collected using a purposive sampling method that adjust the inclusion and exclusion criteria. Data analysis using SPSS 23 software with logistic regression.Results: (1) There is a significant correlation of HbA1c levels and chronic complication of type 2 diabetes mellitus patients in UNS Hospital. (2) HbA1c score of 6.5% or above is best cutoff to use for determining whether type 2 diabetes mellitus was developing chronic problems. (3) The prevalence of the organ with the most involvement in complication is cardiovascular (51,4%).Conclusion: There is a significant correlation of HbA1c levels and chronic complication of type 2 diabetes mellitus in UNS Hospital with cardiovascular as the organ with the most involvement.
Co-Authors Aliyah Roselyn, Nadiya Arifin Helmi Fakhruddin Siti Munawaroh Sukmagautama, Coana