Adolescents in Indonesia often face various challenges, such as academic pressure, interpersonal relationship dynamics, and the influence of social media, which can affect their Psychological Well-Being . Several studies have shown that the majority of high school students in Indonesia have a moderate level of Psychological Well-Being . This study aimed to examine the relationship between Emotional Intelligence and Self-Esteem on Psychological Well-Being in 235 tenth-grade students at SMAN 2 Klaten. The study used a quantitative correlational approach with probability sampling through a cluster random method. Data were collected using three instruments: Ryff's Psychological Well-Being Scale (Ryff, 1989), the Wong and Law Emotional Intelligence Scale (WLEIS; Goleman, 1995), and the Rosenberg Self-Esteem Scale (Rosenberg, 1965). All instruments were tested for validity and reliability, with validity coefficients ranging from 0.35–0.72 and Cronbach's Alpha reliability >0.70, indicating adequate internal consistency. The results of the regression analysis showed that Emotional Intelligence and Self-Esteem were positively and significantly related to Psychological Well-Being , both partially and simultaneously. These findings confirm that these two intrapersonal variables play a crucial role in supporting adolescent mental health. Therefore, it is recommended that schools and students develop emotional skills training programs and Self-Esteem strengthening programs through structured learning and counseling activities to optimally promote Psychological Well-Being Psychological Well-Being Psychological Well-Being Emotional Intelligence Self-EsteemPsychological Well-Being Emotional Intelligence Self-EsteemPsychological Well-Being Emotional Intelligence Self-EsteemPsychological Well-Being.