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All Journal The ASEAN Journal of Military and Preventive Medicine
Mahfudz Shidiq
Faculty of Medicine and Health Sciences, Republic of Indonesia Defense University, Bogor, Indonesia

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Heat Therapy Intervention and Pulse Dose Itraconazole as Combination Treatment for Chromoblastomycosis: An Unusual Case Report Sissy Sissy; Clara Virginia Allun; Daniel Ahmad Romero; Mahfudz Shidiq
The ASEAN Journal of Military and Preventive Medicine Vol. 1 No. 1 (2024): January
Publisher : Perkumpulan Kedokteran Militer

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/ajmpm.v1i1.3

Abstract

Chromoblastomycosis (CBM) is a rare chronic fungal infection caused by dematiaceous fungi, presenting a significant challenge in Indonesia. This case involves a 54-year-old man who reported a lump on his right leg persisting for 10 years. Examination revealed multiple erythematous nodules with well-defined borders and a verrucous surface, forming a linear pattern around the ankle, some covered by brownish crusts. The patient denied itching and pain in the lesions. The initial diagnosis of chromoblastomycosis was confirmed through culture and histopathology. Treatment involved pulsed doses of intraconazole and heat therapy. Remarkably, lesions significantly improved after one month, underscoring the efficacy of combination therapy for chromoblastomycosis. Pulsed dose itraconazole enhances treatment compliance with its cost-effectiveness, while heat therapy, as a physical intervention, proves to be an easily administered option with promising efficacy. Considering the prolonged management required for CBM, it is imperative to factor in the patient's socioeconomic condition during treatment planning.
Co-Authors Clara Virginia Allun Daniel Ahmad Romero Sissy Sissy