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All Journal African Multidisciplinary Journal of Sciences and Artificial Intelligence Open Access DRIVERset African Journal of Biochemistry and Molecular Biology Research Open Access DRIVERset African Journal of Sciences and Traditional Medicine Open Access DRIVERset Kwaghe International Journal of Sciences and Technology Open Access DRIVERset
Mathew, Twan Sale
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Nursing Public Health Social Sciences

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Journal : Open Access DRIVERset

 1 
The Devastating Impact of Heavy Metal Contamination on Plant Growth and Development: Unveiling Phytotoxicity and Exploring Remediation Strategies Ataitiya, Hylalibiya; Ahmad, Kabiru Bashir; Kaugama, Aminu Ado; Idris, Shamsu Abdullahi; Adam, Ansar Bilyaminu; Abubakar, Musa Yahaya; Mathew, Twan Sale
African Journal of Sciences and Traditional Medicine Vol 1 No 1 (2024): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v1i1.3495

Abstract

Heavy metal contamination poses a significant threat to plant growth and development, leading to reduced crop yields, impaired ecosystem functioning, and potential human health risks. This review provides a comprehensive overview of the phytotoxic effects of heavy metals on plant species, highlighting the mechanisms of uptake, transport, and accumulation. We explore the devastating impacts on plant morphology, physiology, and biochemistry, including altered root architecture, reduced photosynthesis, and impaired reproductive development. This review highlights the urgent need for effective remediation approaches to mitigate the phytotoxic effects of heavy metals and ensure sustainable ecosystem functioning. We identify knowledge gaps and future research directions, emphasizing the importance of interdisciplinary collaboration to address this critical environmental issue.
Phytochemical Analysis of Carrot, Red Pepper, Spinach and Lettuce Cultivated at Ajiwa, Batagarawa, Lambun Sarki and Dankama Vegetable Farms, Katsina State, Nigeria Dahiru, Sabiru; Salele, Yazid; Mathew, Twan Sale; Adam, Ansar Bilyaminu
African Journal of Sciences and Traditional Medicine Vol 1 No 1 (2024): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v1i1.3724

Abstract

Katsina state for long has been a major aggregation centre for cash crops including vegetables due to the availability of suitable land and adequacy of water supply, phytochemical analysis of vegitables cultivated at , batagarawa, lambun sarki and dankama vegetable farms were investigated, This study investigates the metabolites present in sample, the presence of tannins, flavonoids and saponins were tested. The results of the study showed the presence flavonoids, and tannins in lettuce, red pepper showed the presence only flavonoids, carrot showed the presence flavonoids, saponin and tannins, spinach showed the presence of tannin and saponin, while lettuce showed the presence Tannins, Saponins, Flavonoids. Therefore, lettuce, spinach and carrot could serve as potential source of natural antioxidants, red pepper could serve as a source of both antioxidant and anti-inflammatory.
Challenges and Opportunities in Repurposing Natural Products for the Treatment of Neglected Trophical Diseases: A Review of Scaffold Optimization Strategies Abubakar, Musa Yahaya; Mathew, Twan Sale; Shamsuddeen, Ruslan; Abdullahi, Saeed; Bilyamin, Ansar; Chinedu, Emmanuel Kinsley
African Journal of Sciences and Traditional Medicine Vol 1 No 1 (2024): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v1i1.3725

Abstract

Neglected Tropical Diseases (NTDs) are serious health issues that affect the entire world, especially in low-income tropical and subtropical areas, yet they do not get enough facilities. Natural items have great potential for treating NTD because of their varied chemical scaffolds. Nevertheless, there are a number of difficulties in optimizing these scaffolds for drug development. Attempts at synthesis and modification are complicated by the structural complexity of natural compounds. Economic and regulatory hurdles also obstruct advancement. Despite these difficulties, there are plenty of chances. Natural products are a significant source of structural variety that makes them ideal for drug discovery. developments in biotechnology and synthetic biology. Sustainable production is improved via biotechnology. Targeted optimization is made easier by advances in computer power and molecular understanding. Research collaborations can expedite the process of discovery and development. Finding efficient scaffolds can be done quickly by looking for NTD activity in already-existing natural product libraries. By tackling these issues scientifically and cooperatively, we can develop novel, practical, and affordable treatments for non-traumatic disabilities (NTDs), which will eventually improve the health of impacted communities.
Co-Authors Abdullahi, Saeed Abubakar, Musa Yahaya Adam, Ansar Bilayamin Adam, Ansar Bilyamin Adam, Ansar Bilyaminu Ahmad, Kabiru Bashir Ataitiya, Hylalibiya Bilyamin, Ansar Chinedu, Emmanuel Kinsley Dahiru, Sabiru Haladu, Mohammed Haladu, Muhammed Idris, Abdullahi Mustaph Idris, Abdullahi Mustapha Idris, Shamsu Abdullahi Kaugama, Aminu Ado Mohammad, Haladu Muhammad, Haladu Mahmud Muhammad, Shittu Abubakar Musa, Haruna Reuben, Pambani Salele, Yazid Sani, Ibrahim Shamsuddeen, Ruslan Shamsudden, Ruslan