Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal African Journal of Biochemistry and Molecular Biology Research Open Access DRIVERset
I, Okafor A.
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Enhancing the Extraction of 6-Gingerol from Zingiber officinale Rhizomes Using Dry Vacuum Evaporation to Improve Bioavailability I, Okafor A.; O, Ogar B.
African Journal of Biochemistry and Molecular Biology Research Vol 1 No 2 (2024): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v1i2.3817

Abstract

This study optimized the extraction and purification of 6-gingerol from ginger (Zingiber officinale) rhizomes through a multi-step process. Initially, cold maceration ethanol extraction was performed, followed by hexane defatting to remove impurities. Further purification was achieved through liquid-liquid extraction using a sequential solvent system of chloroform and ethyl acetate. The resulting extract was then fractionated using silica gel column chromatography with methanol, and finally concentrated using dry vacuum evaporation to minimize heat-induced degradation. HPLC analysis confirmed a significant concentration of 6-gingerol (33 mg/g) in the final extract. Thus, optimized method demonstrates an effective approach to produce high-quality ginger extracts enriched in 6-gingerol, with potential applications in pharmaceutical or nutraceutical products.
Enhancing the Extraction of 6-Gingerol from Zingiber officinale Rhizomes Using Dry Vacuum Evaporation to Improve Bioavailability I, Okafor A.; O, Ogar B.
African Journal of Biochemistry and Molecular Biology Research Vol 1 No 2 (2024): African Journal of Biochemistry and Molecular Biology Research
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajbmbr.v1i2.3817

Abstract

This study optimized the extraction and purification of 6-gingerol from ginger (Zingiber officinale) rhizomes through a multi-step process. Initially, cold maceration ethanol extraction was performed, followed by hexane defatting to remove impurities. Further purification was achieved through liquid-liquid extraction using a sequential solvent system of chloroform and ethyl acetate. The resulting extract was then fractionated using silica gel column chromatography with methanol, and finally concentrated using dry vacuum evaporation to minimize heat-induced degradation. HPLC analysis confirmed a significant concentration of 6-gingerol (33 mg/g) in the final extract. Thus, optimized method demonstrates an effective approach to produce high-quality ginger extracts enriched in 6-gingerol, with potential applications in pharmaceutical or nutraceutical products.
Co-Authors O, Ogar B.