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All Journal JURNAL ANALIS LABORATORIUM MEDIK Bali Medika Jurnal Jurnal Media Sains Jurnal Ilmiah Medicamento Jurnal Kesehatan Terpadu Pena Dimas: Jurnal Pengabdian Masyarakat Multidisciplinary Indonesian Center Journal Bali International Scientific Forum
Sutrisna Putra, I Gusti Putu Agus Ferry
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Journal : Bali International Scientific Forum

 1 
Pengaruh Variasi Dosis Dekstrometorfan Terhadap Kadar Serum Glutamic Pyruvic Transaminase dan Gamma Glutamyl Transferase Pada Tikus Wistar Iswari, Ni Wayan Gita; Putra, I Gusti Putu Agus Ferry Sutrisna; Widayanti, Ni Putu
Bali International Scientific Forum Vol. 1 No. 1 (2020): Bali International Scientific Forum
Publisher : Bali International University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34063/bisf.v1i1.127

Abstract

Background: Dextromethorphan is an antitussive drug commonly found in cough medicine, besides that dextromethorphan has the function as an expectorant or cough suppressant. Dextromethorphan is widely misused by the community, especially adolescents. Objective: to determine the effect of variations in dextromethorphan doses on SGPT and GGT levels in wistar rats. Method: using an experimental research design using the pretest-posttest control group design method. The analysis technique uses SPSS One Way Annova analysis. Results: Giving doses of dextromethorphan can increase levels of SGPT and GGT, namely in group P1 of 5.68% and 14.06%, P2 of 16.67% and 26.82%, and P3 of 20.95% and 36.54 %. Conclusion: There are effects of variations in dextromethorphan doses on increasing levels of SGPT and GGT in Wistar rats. Suggestion: It is necessary to conduct examination parameters and need to do research with more varied and longer doses.
Pengaruh Ekstrak Batang Dan Daun Pakis Sayur (Diplazium Esculentum) Terhadap Kadar Hemoglobin, Hematokrit dan Jumlah Eritrosit Pada Tikus Putih Jantan yang Disuntikkan Natrium Nitrit (NaNO2) Sashmita, Geby; Putra, I Gusti Putu Agus Ferry Sutrisna; Widayanti, Ni Putu
Bali International Scientific Forum Vol. 1 No. 1 (2020): Bali International Scientific Forum
Publisher : Bali International University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34063/bisf.v1i1.128

Abstract

Background: Anemia is a decrease in hemoglobin level, hematocrit value and the number of erythrocytes in the body due to a lack of iron intake in the body. One plant that is rich in iron is vegetable ferns (diplazium esculentum). This research was conducted at the Animal Unit Laboratory of the Faculty of Medicine, Udayana University. Objective: To determine the effect of vegetable ferns and stem extracts on hemoglobin levels, hematocrit values and the number of erythrocytes. Method: This study uses true experimental design. Results: The results of this study prove that stem fern extract and vegetable ferns can increase hemoglobin levels, hematocrit values and the number of erythrocytes in experimental male rats with a dose of 0.18 grams, 0.36 grams and 0.72 grams. Conclusion: There was a significant effect on male white mice with anemia treatment after being given stem and vegetable fern leaf extract, where the administration of vegetable fern extracts and ferns with a dose of 0.72 grams resulted in an increase in hemoglobin levels of 52.07%, a hematocrit value of 32, 91% and the number of erythrocytes is 29.41%.
Pengaruh Pemberian Variasi Dosis Rifampisin Terhadap Kadar Gamma Glutamyl Transferase dan Alkaline Phosphatase Pada Tikus Putih Galur Wistar Jeharu, Sofiana Agustin; Putra, I Gusti Putu Agus Ferry Sutrisna; Widayanti, Ni Putu
Bali International Scientific Forum Vol. 1 No. 1 (2020): Bali International Scientific Forum
Publisher : Bali International University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34063/bisf.v1i1.129

Abstract

Background: Tuberculosis is a contagious infectious disease caused by the bacterium Mycobacterium tuberculosis. Rifampicin is a first-line drug for the treatment of tuberculosis. Rifampicin has a bactericidal effect and the sterilizing effect is effective against intracellular and extracellular tuberculosis bacteria. In addition, one of the side effects of using rifampicin is hepatotoxicity. Objective: to determine the effect of rifampicin drug dosage on GGT and ALP levels in wistar rats. Methods: using an experimental study design with the pretest and posttest control group design method with the use of test animals 24 wistar rats divided into 4 groups. The technique of analyzing data using SPSS One Way Annova was followed by a Post-Hoc Test. Results: The results of the study showed an average increase in GGT levels in treatment groups 1, 2 and 3 was 29.5%, 40.9% and 55.4% and the mean increase in ALP levels in treatment groups 1, 2 and 3 was 27.5 %, 46.7% and 53.5%. The One Way ANOVA test results obtained p = 0.00 (p <0.05) followed by the Post Hoc test obtained α> 0.05. Conclusions: there was a significant effect on the levels of GGT and ALP after the administration of dose variations of the rifampicin drug in wistar strain white rats.
Perbandingan Hasil Creatinin Clirens Test (CCT) dan Estimasi Laju Filtrasi Glomerulus (eLFG) Pada Pasien Kemoterapi di Rumah Sakit Prima Medika Wijayanti, Sariati; Putra, I Gusti Putu Agus Ferry Sutrisna; Juliantara, I K. Putra
Bali International Scientific Forum Vol. 1 No. 1 (2020): Bali International Scientific Forum
Publisher : Bali International University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34063/bisf.v1i1.130

Abstract

Background: Creatin clirens test (CCT) is a reliable examination to estimate LFG. To solve some weaknesses in the creatinine clirens test, we can use estimation of glomerulus filtration rate (eLFG). Estimation of glomerulus filtration rate (eLFG) can be used as the Cockcroft Gault (CG) formula, Modification of Diet in Renal Disease (MDRD), and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI). Each formula has advantages and disadvantages. Objective: The aim of this study was to compare the results of CCT with eLFG (CG, MDRD, CKD-EPI) and the correlation between results of CCT and eLFG (CG, MDRD, CKD-EPI). Method: Research on the comparison of the results of creatinine clarity test (CCT) and estimation of glomerulus filtration rate (eLFG) is a type of comparative analytical study with a retrospective approach. Result: The results showed that there were no differences in the results of CCT and eLFG (CG, MDRD, CKD-EPI) (p > 0.05). In addition, there is correlation between CCT and eLFG (CG, MDRD, CKD-EPI) (r > 0.05). Conclusion: It can be concluded that there is no difference in the results of CCT and eLFG (CG, MDRD, CKD-EPI). In addition, there is a correlation between the results of CCT and eLFG (CG, MDRD, CKD-EPI).
Co-Authors Aprilianti, Ni Kadek Dwi Dewi Puspita Apsari Dewi Puspita Apsari Diah Prihatiningsih I K. Putra Juliantara Iswari, Ni Wayan Gita Jeharu, Sofiana Agustin Lestari, Ni Kadek Yuni Ni Luh Putu Ari Sukmayanti Ni Putu Widayanti Ni Wayan Trisnadewi, Ni Wayan Pramesti, Theresia Anita Putri, Maylina Putu Gede Subhaktiyasa Sashmita, Geby Setiawati, Ni Putu Dinda Sita, A.A. Sagung Ranya Sri Idayani, Sri Sukmayanti, Ni Luh Putu Ari Sukmayanti, Ni Luh Putu Ari Utami, A. A Sagung Ranya Sita Damara Wijayanti, Sariati