Siba, Salma salsabila
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Pengaruh Suplementasi Vitamin D Pada Kesehatan Tulang Ramadhani, Fitri; Siba, Salma salsabila; Yulia, Asri
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Vol 5 No 2: Desember 2024
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

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Abstract

Vitamin D is a key nutrient that plays an essential role in maintaining bone integrity through the regulation of calcium and phosphorus metabolism. Prolonged vitamin D deficiency leads to reduced bone mineral density and an increased risk of osteoporosis and fractures, particularly among older adults. This article presents a literature review of three scientific journals that examine the relationship between vitamin D supplementation, bone mineral density, and fracture prevention. The synthesized literature indicates that a supplementation dose of 800–1000 IU/day—especially when combined with calcium—provides significant protective effects on bone health. Higher doses do not offer additional meaningful benefits and may increase the risk of hypercalcemia. Thus, vitamin D serves as a strategic preventive intervention that can be considered for maintaining long-term bone health