reproductive health-related issues. In the context of rapidly advancing digital technology, an individual's capacity to seek, comprehend, critically assess, and practically utilize online sexual health information collectively referred to as digital sexual health literacy (DSHL) has emerged as a significant determinant shaping reproductive health behaviors. Nevertheless, empirical evidence exploring DSHL and its association with reproductive health behavior among high school female students within the Indonesian context remains considerably scarce. This study aimed to examine the association between digital sexual health literacy and reproductive health behavior among female students enrolled at SMA Negeri 1 Selesai, Langkat Regency, North Sumatra Province. An observational analytical approach with a cross-sectional study design was employed. The minimum required sample size was calculated at 97 respondents, subsequently adjusted to 108 respondents to accommodate a 10% anticipated drop-out rate. Participants were recruited using proportionate stratified random sampling. A structured questionnaire served as the primary data collection instrument. Data were analyzed across three levels: univariate, bivariate using the chi-square test, and multivariate using binary logistic regression. The majority of respondents demonstrated a moderate level of DSHL (45.4%), while poor reproductive health behavior was prevalent among more than half of the study sample (52.6%). The chi-square analysis revealed a statistically significant association between the two variables (p=0.000; OR=4.21; 95% CI=2.14–8.29). Among all dimensions examined in the multivariate analysis, the ability to evaluate digital health information emerged as the most influential predictor (OR=3.133). A statistically significant relationship exists between digital sexual health literacy and reproductive health behavior in adolescent females. Consequently, enhancing DSHL through the development and implementation of digitally-based health education programs warrants prioritization as a key reproductive health intervention strategy.