Background: Self-efficacy plays a crucial role in enhancing healthcare professionals’ confidence and assertiveness when conveying critical clinical information. Meanwhile, self-disclosure facilitates healthy openness, fosters team trust, and promotes interprofessional collaboration. Structured communication using the SBAR (Situation, Background, Assessment, Recommendation) framework is therefore essential to improve patient safety and reduce communication errors in clinical settings. Purpose: This study aimed to identify the relationship between self-efficacy and self-disclosure with the effectiveness of SBAR communication among healthcare professionals in a private hospital X in Tangerang. Methods: This study employed a quantitative correlational design with a cross-sectional approach. The population consisted of healthcare professionals working in a private hospital X. A proportional random sampling technique was used, resulting in a total sample of 140 respondents. Self-efficacy was measured using the General Self-Efficacy Scale (GSES), self-disclosure was assessed using the Self-disclosure Index (SDI), and SBAR communication effectiveness was measured using the SBAR Effectiveness Questionnaire. Data were analyzed using the Chi-square test for bivariate analysis and logistic regression for multivariate analysis Result: The findings showed that 67 respondents (47.2%) had high self-efficacy and 73 respondents (51.4%) had low self-efficacy. High self-disclosure was reported in 82 respondents (57.7%), while 58 respondents (40.8%) had low self-disclosure. Regarding SBAR communication, 67 respondents (47.9%) demonstrated effective communication, whereas 73 respondents (52.1%) were categorized as less effective. Bivariate analysis revealed a significant relationship between self-efficacy and SBAR communication effectiveness (p-value = 0.000; OR = 8.307) and between self-disclosure and SBAR communication effectiveness (p-value = 0.004; OR = 3.292). Implication: Healthcare professionals with high self-efficacy were approximately 8.3 times more likely to demonstrate effective SBAR communication compared to those with low self-efficacy. Similarly, respondents with higher self-disclosure were about 3.2 times more likely to exhibit effective SBAR communication. These findings highlight the importance of strengthening psychological factors, particularly self-efficacy and self-disclosure, to enhance structured communication and ultimately improve patient safety outcomes