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Formulasi Effervescent Rumput Laut sebagai Antihipertensi Mandiricha, Tara; Inassani, Lustyafa; Malik, Ibnu; Harum, Zahrotul Hasanah; Setiawan, Meddy
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 7, No 1 (2014)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (318.588 KB)

Eucheuma spinosum belongs to rhodophyceae seaweed that comprises bioactive peptides. Those peptides worked by decreasing blood pressure, i.e. ACE inhibitor drugs. These studies are conducted to determine reaction of Eucheuma spinosum distribution as natural ACE inhibitor in form of effervescent formulation. These study were true experimental wiith pre-post test only control group. Sample consists of 28 Wistar rats, divided into 4 groups; a group of control (K) and 3 groups of experiment (P1, P2, P3) were given Eucheuma spinosum, dose 200 mg/kgBW/day, 400 mg/kgBW/day, & 600 mg/kgBW/day. The result shows that there is an effect of Eucheuma spinosum distribution to the blood pressure of hypertensive rats.Keywords : Effervescent Eucheuma spinosum, hypertension, bioactive peptide, ACE Inhibitor

Formulasi Effervescent Rumput Laut sebagai Antihipertensi Mandiricha, Tara; Inassani, Lustyafa; Malik, Ibnu; Harum, Zahrotul Hasanah; Setiawan, Meddy
Jurnal Farmasi Indonesia Vol 7, No 1 (2014)
Publisher : Jurnal Farmasi Indonesia

Eucheuma spinosum belongs to rhodophyceae seaweed that comprises bioactive peptides. Those peptides worked by decreasing blood pressure, i.e. ACE inhibitor drugs. These studies are conducted to determine reaction of Eucheuma spinosum distribution as natural ACE inhibitor in form of effervescent formulation. These study were true experimental wiith pre-post test only control group. Sample consists of 28 Wistar rats, divided into 4 groups; a group of control (K) and 3 groups of experiment (P1, P2, P3) were given Eucheuma spinosum, dose 200 mg/kgBW/day, 400 mg/kgBW/day, & 600 mg/kgBW/day. The result shows that there is an effect of Eucheuma spinosum distribution to the blood pressure of hypertensive rats.Keywords : Effervescent Eucheuma spinosum, hypertension, bioactive peptide, ACE Inhibitor

Identifikasi Faktor Resiko Hipertensi pada Masyarakat Pesisir Pantai Isbandiyah; Mandiricha, Tara; Rahmanda, Risha Ayu; Permadi, Fauzi Jati; Anugrah, Dimas Fajar; Amalia, Risky; Cahya, Linggar Dwi
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 4 No. 3 (2024): Februari
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/comphijournal.v4i3.189

Penyakit hipertensi diperkirakan meningkat sekitar 60% pada tahun 2025 dengan hampir 1,5 juta kematian (9,4% dari total kematian) setiap tahunnya. Kejadian hipertensi pada masyarakat pesisir pantai akibat terbiasa mengkonsumsi makanan tinggi garam terutama dari hasil tangkapan atau pengasinan ikan. Tujuan studi literatur ini untuk mengetahui faktor resiko hipertensi masyarakat pesisir pantai. Menggunakan studi literatur melalui beberapa jurnal nasional dan internasional yang diperoleh dari 30 sumber referensi melalui pencarian di PubMed dan Google Scholar yang terpublikasikan dalam rentang 5 tahun terakhir. Diperoleh sebanyak 30 jurnal dengan teks lengkap yang memenuhi kriteria inklusi serta memuat faktor resiko yang signifikan berhubungan dengan kejadian hipertensi pada masyarakat pesisir pantai. Berdasarkan studi literatur 30 jurnal didapatkan bahwa faktor resiko hipertensi masyarakat pesisir pantai terbagi menjadi faktor resiko yang tidak dapat dimodikfikasi, meliputi usia, jenis kelamin, genetik dan faktor yang dapat dimodifikasi, berhubungan dengan gaya hidup dan sosioekonomi. Faktor resiko hipertensi masyarakat secara umum sama dengan masyarakat pada umumnya. Beberapa faktor gaya hidup seperti konsumsi garam, pekerjaan, pengetahuan dan sosioekonomi masyarakat pesisir berperan terhadap kejadian hipertensi lebih besar daripada masyarakat umumnya. Kata Kunci: hipertensi, faktor resiko, masyarakat pesisir

Indications and findings of upper gut endoscopy in pediatric patients Hasanah, Annisa'; Mandiricha, Tara
International Journal of Public Health Science (IJPHS) Vol 13, No 4: December 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i4.24340

Children undergoing more gastrointestinal endoscopies without the necessary indications risk serious adverse effects. Therefore, upper GI (UGI) endoscopy examination requires selective indications to minimize the risk of unnecessary use of UGI endoscopy. This study aimed to analyze the indications for endoscopy based on the main UGI complaints in pediatric patients at Dr. Saiful Anwar General Hospital Malang. A retrospective analysis of the first diagnostic endoscopy in children was conducted between July 2022 to July 2023 at Dr. Saiful Anwar General Hospital Malang. Among 60 patients were included with an age of 0-15 years old; 51.7% were boys and 48.3% were girls. The results showed recurrent abdominal pain (RAP) as the primary cause of UGI endoscopic indications (38.3%), followed by blood vomiting (33.3%), acute abdominal pain (21.6%), and prolonged vomiting (6.66%). In conclusion, recurrent abdominal pain in children is the most typical reason for upper gastrointestinal endoscopy, and persistent gastritis is the most typical underlying condition.

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