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Bioaktif Ekstrak Buah Pare (Momordica Charantia) dalam Regulasi Glukosa Darah dan Resistensi Insulin : Literature Review Nurul Hikmah; Sri Julyani M; Dian Fahmi Utami
KOLONI Vol. 5 No. 2 (2026): JUNI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v5i2.867

Abstract

Diabetes mellitus is characterized by elevated blood glucose levels exceeding the normal fasting range of 80-90 mg/dL or the non-fasting range of 140-160 mg/dL. Diabetes mellitus encompasses a group of metabolic diseases characterized by hyperglycemia due to abnormalities in insulin secretion, insulin action, or both. The research methodology used was a literature review. This study aims to examine the function of bioactive bitter melon (Momordica charantia) fruit extract in regulating blood glucose and insulin resistance. This subject is important because of the increasing incidence of diabetes mellitus, which requires effective and safe complementary therapy solutions. The methodology used involved a literature review, analyzing 10 scientific journals sourced from the ResearchGate, PubMed, and Google Scholar databases, which were then selected according to predetermined inclusion and exclusion criteria. The analysis used a content analysis method to ensure significant conclusions. The research findings indicate that bitter melon fruit extract has considerable potential to lower blood glucose levels and improve insulin resistance due to its bioactive compounds, including charantin, polypeptide-p, flavonoids, and polysaccharides. The mechanisms include enhancing insulin sensitivity, inhibiting gluconeogenesis, and providing antioxidant and anti-inflammatory effects. Therefore, bitter melon extract has potential as a complementary therapy in the management of diabetes mellitus, although further research is needed to confirm its long-term effectiveness and safety.
Hubungan Work Life Balance Dengan Kinerja Perawat Di Instalasi Rawat Inap Rumah Sakit Ibnu Sina YW-UMI Kota Makassar Riani Nur Afiah Namudat; Wardiah Hamzah; Nurul Hikmah
Window of Public Health Journal Vol. 7 No. 2 (2026)
Publisher : Pusat Kajian dan Pengelolaan Jurnal FKM UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/rdgg3514

Abstract

Nurses play a crucial role in hospital services, making optimal performance essential for healthcare quality. An imbalance between work and personal life (work-life balance) may negatively affect nurses’ performance. This study aimed to analyze the relationship between work-life balance and nurse performance in the inpatient unit of Ibnu Sina YW-UMI Hospital, Makassar.This study employed a quantitative, cross-sectional design. A total of 53 nurses were selected using cluster purposive sampling. The independent variable was work-life balance, which included three dimensions: time balance, involvement balance, and satisfaction balance. The dependent variable was nurse performance. Data were collected using a structured questionnaire and analyzed using the chi-square test at the 0.05 significance level. The results showed that most nurses had good work-life balance and performance. Bivariate analysis indicated a significant relationship between all dimensions of work-life balance (time, involvement, and satisfaction) and nurse performance (p-value = 0.000). Nurses with better work-life balance tended to perform better than those with poorer balance. In conclusion, work-life balance is significantly associated with nurse performance. Therefore, hospitals should pay greater attention to maintaining nurses’ work-life balance by optimizing workload management and work schedules to improve overall performance.