Article Per Year (5 Year)
p-Index From 2021 - 2026
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All Journal International Journal of Health and Pharmaceutical (IJHP)
Lisdawaty Siregar
Department of Public Health, Adiwangsa University, Jambi, Jambi 36138, Indonesia
Nursing Public Health

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The Relationship Between Chronic Kidney Disease and the Severity of Pruritus in Patients Undergoing Hemodialysis at Royal Prima General Hospital in Medan Popy Fazriani; Ade Arhamni; Lisdawaty Siregar
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.483

Abstract

Chronic kidney disease-associated pruritus represents a prevalent complication that significantly impairs hemodialysis patient quality of life. This study examined the relationship between hemodialysis duration and uremic pruritus severity. An analytical cross-sectional design enrolled 34 chronic kidney disease patients receiving maintenance hemodialysis at Royal Prima General Hospital, Medan. Data collection utilized questionnaires and medical records; purposive sampling identified meeting participants inclusion criteria. Univariate analysis described demographic and clinical characteristics using frequency distributions. Bivariate chi-square analysis tested associations between hemodialysis duration (categorized as less than 6 to 12 months, 13 to 24 months, and greater than 24 months) and pruritus severity (mild, moderate, severe) using IBM SPSS Statistics software. Results demonstrated a highly significant association between dialysis duration and pruritus severity (χ² = 17.661, p = 0.000), with severe pruritus occurring in 0% of early-stage dialysis patients, 16.7% of intermediate-duration patients, and 82.4% of long-term recipients. Extended hemodialysis exposure correlates directly with progressive pruritus escalation through cumulative uremic toxin accumulation and inflammatory activation. These findings substantially systematic pruritus screening and multimodal management implementation for all dialysis patients, particularly targeting long-term recipients experiencing substantial symptom burden.
The Relationship Between Stress Levels And The Severity of Acne Vulgaris In Medical Students At Prima Indonesia University Class of 2022 Tarisa Mudhia Putri; Ade Arhamni; Lisdawaty Siregar
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.484

Abstract

Acne vulgaris is a chronic skin disease of the pilosebaceous follicle with multifactorial etiology. Psychological stress represents one significant etiological factor, as stress activates the hypothalamic-pituitary-adrenal axis, stimulating corticotropin-releasing hormone, which plays an important role in acne vulgaris development. Medical students experience high academic burdens that potentially cause stress, making them more susceptible to acne vulgaris with varying severity degrees. This cross-sectional analytic observational study investigated the relationship between stress levels and acne vulgaris severity among medical students at Universitas Prima Indonesia, class of 2022. A total of 35 respondents were selected through stratified random sampling. Data were collected using the Depression Anxiety Stress Scale-42 to measure stress levels and the Lehmann Acne Grading System to assess acne severity. Results showed that 60.0% of respondents experienced moderate stress, while 45.7% exhibited mild acne vulgaris. Chi-Square testing revealed a statistically significant relationship between stress levels and acne severity (p = 0.000). A clear dose-response pattern emerged, with mild stress predominantly associated with mild acne, moderate stress with moderate acne, and severe stress universally manifesting as moderate-to-severe acne manifestations. This investigation concludes that a significant correlation exists between stress levels and acne vulgaris severity in this population, necessitating stress management interventions and mental health education programs to reduce acne severity risk among medical students.
Co-Authors Ade Arhamni Popy Fazriani Tarisa Mudhia Putri