Background: The oropharyngeal Leak pressure (OLP) and the minimum effective cuff volume are the two most important determinants of the clinical performance of any supraglottic airway (SGA) device. This study aims to evaluate the clinical performance of the Blockbuster LMA compared with the LMA ProSeal. Methods: One-Hundred patients (18-65 years) posted for elective surgeries under general anesthesia were prospectively randomized into group P (LMA ProSeal) and Group B (Blockbuster LMA). The primary outcome was to measure the OLP at 5 and 30 min after device insertion, and, secondarily, to compare the minimum effective cuff volume to prevent leak, ease and time of insertion, number of attempts, leak fraction, anatomical position of the devices, and adverse respiratory events, if any. Result: The OLP of LMA ProSeal was lower than Blockbuster LMA (28.14 ± 2.79 cmH2O versus 32.62 ± 2.66 cmH2O at 5 minutes and 29.28 ± 3.1 cmH2O versus 33.82 ± 2.55 cmH2O at 30 minutes). The cuff pressure exerted by the Blockbuster LMA at the minimum effective volume to prevent leak was higher than that of the LMA ProSeal. The first attempt success rate and Brimacombe score were higher in Blockbuster LMA. The airway-sealing quality and the incidence of postoperative adverse respiratory events were similar between the two groups. Conclusion: Blockbuster LMA has a higher OLP, a better first-attempt success rate, and an anatomical position than LMA ProSeal, with higher pressure at the minimum effective volume of cuff inflation to prevent leaks, along with the added advantage of acting as a conduit for intubation.