Andreas Rony Wijaya
Department of Statistics, Universitas Sebelas Maret

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A Comparative Study of PCA-Based Dimensionality Reduction and Best Subset Selection in Disease Classification Andreas Rony Wijaya; Atika Ratna Dewi; Muhammad Bayu Nirwana; Respatiwulan Respatiwulan; Sri Sulistijowati Handajani
JTAM (Jurnal Teori dan Aplikasi Matematika) Vol 10, No 3 (2026): July
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jtam.v10i3.38265

Abstract

Real-world datasets often contain many variables, some of which may be irrelevant or redundant. To build an effective classification model, it is important to simplify the data by keeping only the most influential features. One common approach that can be used for selecting the most influential variables is feature selection. However, when dealing with many variables, removing some may result in the loss of information. Hence, it is also necessary to consider methods that can simplify the model while retaining most of the information from the original variables. Dimensionality reduction is one such approach that effectively addresses this issue. This study employs a comparative quantitative research approach to evaluate the effectiveness of principal component analysis (PCA) as a dimensionality reduction method and best subset selection as a feature selection method in improving classification performance. The study utilizes a heart disease dataset from the UCI Machine Learning Repository consisting of 303 observations and 13 predictor variables as a case study. Both approaches are applied to reduce the number of predictor variables and make the model more interpretable. After applying both methods, three classification models — logistic regression, naïve Bayes, and linear discriminant analysis — are trained and evaluated using accuracy, recall, precision, and F1-score, and the results are further illustrated through ROC curves. Feature selection using best-subset selection yields seven variable combinations with the most significant predictors, whereas PCA requires eight principal components to explain 80% of the total variation.  The best classification performance was obtained using the feature-selected dataset, achieving an accuracy of 87% and an AUC of 0.93, outperforming both the original dataset model and the PCA-reduced dataset model. These results show that feature selection using best subset selection provides a better balance between simplicity and classification performance. Furthermore, the models obtained after feature reduction, both from best subset selection and PCA, still maintain good predictive ability as indicated by their relatively high AUC values.
Application of Proportional Hazard and Additive Models in the Survival Analysis of Breast Cancer Patients Muhammad Bayu Nirwana; Tiara Fitri Adani; Kayla Argya Puruhita; Andreas Rony Wijaya; Hasih Pratiwi; Silvina Rosita Yulianti
JTAM (Jurnal Teori dan Aplikasi Matematika) Vol 10, No 3 (2026): July
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jtam.v10i3.37028

Abstract

Breast cancer is the most common type of cancer among women and one of the highest causes of death among other types of cancer. This study aims to evaluate the methodological advantages of additive hazard models over the multiplicative Cox model in identifying temporal risk factors for breast cancer survival. Using secondary data from 1458 patients and 10 covariates, applying three methods, Cox proportional hazards model, Lin-Ying additive hazard model, and Aalen additive hazard model. The proportional hazard assumption test indicated that Cox regression model did not fully satisfy the assumption; therefore, the Lin–Ying and Aalen additive models were applied. In the Lin–Ying models, hormonal therapy, radiotherapy, the Nottingham Prognostic Index (NPI), and tumor size were identified as significant predictors of survival, whereas in the Aalen model, significant factors also included age and chemotherapy in addition to those four covariates. These findings highlight that while the Cox model provides efficient estimation and interpretable hazard ratios, the Lin–Ying and Aalen models offer more robust alternatives when the proportional hazard assumption is violated. The Aalen model was selected based on the results of the Aalen plot. Overall, risk control efforts in breast cancer patients should focus on managing NPI scores and tumor size as well as ensuring appropriate therapies, particularly hormonal therapy and radiotherapy, which have been demonstrated to provide protective effects.