Objective – Observations of research results related to adaptive user interfaces in e-commerce have been widely conducted; however, there is a need for evaluation and assessment of indicators based on user requirements. This study aims to conduct a systematic literature review and bibliometric analysis on adaptive user interfaces for MSMEs, based on existing empirical research. Methodology – The methodology applied is a Systematic Literature Review, using the term “adaptive user interface for MSMEs” in “Article Titles, Abstracts, and Keywords” within the Sciencedirect database, resulting in 5,622 publications from 1998 to 2025. The evaluation was carried out on November 21, 2025. The collected articles were analyzed using bibliometric analysis with VOSviewer software, based on fields of study including computer science, decision science, engineering, social sciences, business, management, accounting, and materials science. Findings – Research on adaptive user interfaces for MSMEs has been extensively conducted in line with the digitalization of the e-commerce sector. The observations sought gaps and indicators in each article. Gaps were identified; however, further research is still needed to provide more specific, comprehensive, and well-founded recommendations. Indicators focus on how to provide ease and comfort for users, as well as offering recommendations to them. Research Limitations – This study used the Sciencedirect database for articles related to adaptive user interfaces for MSMEs. Future research could enhance generalizability by integrating other databases such as the Web of Science.