Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Jurnal Biodjati
Jihan Restu Buana
Undergraduate Program, Faculty of Biology, Universitas Gadjah Mada
Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
The Effects of Pasak Bumi (Eurycoma Longifolia Jack) Product on Liver Histology of Wader Pari (Rasbora Lateristriata Bleeker, 1854) Jihan Restu Buana; Bambang Retnoaji
Jurnal Biodjati Vol 11 No 1 (2026): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v11i1.47944

Abstract

Eurycoma longifolia Jack (commonly known as pasak bumi) is a medicinal plant that contains various bioactive compounds such as eurycomanone, saponins, sterols, and isoprenoids, which are known to exert multiple physiological effects, including on the liver as an organ. This study aimed to examine the effects of pasak bumi root product on liver histology in yellow rasbora (Rasbora lateristriata) as an animal model and to compare the effects between continuous and cyclic (5 days ON, 2 days OFF) administration methods. The experiment lasted 2 weeks, with three treatment groups: control (no extract), continuous administration (P1), and cyclic administration (P2). Observed parameters included liver tissue structure, such as the central vein and hepatocytes arrangement, as well as histological features of hepatocytes. Data were analyzed using one-way ANOVA followed by Duncan’s test. The results showed that pasak bumi administration affected the histological structure of the liver in R. lateristriata, with observable cellular damage including pyknosis, karyorrhexis, and necrosis. Continuous treatment (P2) caused more severe damage than cyclic treatment (P1), which showed tissue structures more similar to those of the control group. Therefore, cyclic administration is considered safer and tends to induce milder liver damage in fish than continuous administration
Co-Authors Bambang Retnoaji