This Author published in this journals
All Journal MEDICINUS
Yogi Haditya
Program Studi Pendidikan Dokter Spesialis Penyakit Dalam, Fakultas Kedokteran, Universitas Udayana/RSUP Prof. dr. I.G.N.G. Ngoerah, Denpasar, Bali, Indonesia

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

Laporan Kasus Hepatopulmonary Syndrome (HPS) pada Pasien Sirosis Hepatis dengan Penyulit Melena Akut dan Orthodeoxia Yogi Haditya; I Ketut Mariadi
MEDICINUS Vol. 39 No. 6 (2026): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/jpeytk40

Abstract

Hepatopulmonary syndrome (HPS) is a complication that frequently occurs in patients with end-stage liver disease. It is characterized by a triad of abnormal arterial oxygenation, intrapulmonary vascular dilatations (IPVD), and chronic liverdisease. A 48-year-old man presented with complaints of shortness of breath for about 3 months, which improved when lying down but worsened when sitting or standing. The patient also reported blackish stool since one day prior to admission and had a history of liver cirrhosis since 2020. Vital signs were normal except for peripheral oxygen saturation, which was 86% when lying down and 79% when sitting. Physical examination revealed anemic palpebra, clubbing finger on hands and foots. Laboratory results revealed anemia, with an increased alveolar-arterial (A-a) gradient of 64.7 mmHg on blood gas analysis. A transthoracic contrast echocardiography (TTCE) or “buble study” was performed and the result show more than 20 microbubles in the left chambers of the heart after 5 cardiac cycles, indicating an intrapulmonary shunt caused by IPVD. These findings confirmed the diagnosis of HPS. Management of HPS is supportive, as there is no specific medical therapy available other than liver transplantation.