<![CDATA[Micro, Small, and Medium Enterprises (MSMEs) make a significant contribution to the Indonesian economy, particularly in employment absorption and as drivers of the real sector. However, MSMEs often face challenges in the distribution aspect, especially related to inefficient delivery routes that result in high operational costs. This study focuses on designing optimal distribution routes for a Cuanki MSME in Garut Regency by applying the heuristic Saving Matrix method combined with the Milk Run system. The research approach used is descriptive quantitative, with data obtained through direct observation, interviews with the business owner, and measurement of distances between customers using Google Maps. The analyzed data include daily customer demand, coordinate points, vehicle capacity, and existing distribution routes. The analysis stages involve the preparation of distance and demand matrices, calculation of distance savings using the Saving Matrix method, and determination of integrated distribution routes using the Milk Run system to combine multiple delivery points in a single trip according to vehicle capacity. The results show a significant improvement in distribution efficiency, indicated by a reduction in total travel distance from 182 km to 156.3 km, a decrease in fuel costs from IDR 236,842.11 to IDR 217,518.80, and monthly operational cost savings of 27.49% compared to actual conditions. These findings demonstrate that the combination of the Saving Matrix method and the Milk Run system is capable of improving distribution performance, reducing logistics costs, and optimizing vehicle capacity utilization.]]>
