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All Journal AcTion: Aceh Nutrition Journal
Eka Yunita Amna
Section of Growth and Development and Social Pediatrics, Section of Pediatric Nutrition and Metabolic Diseases Dr. Zainoel Abidin Hospital, Banda Aceh, Provinsi Aceh
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Vitamin D and calcium status in children with thalassemia beta major: A cross sectional study in Banda Aceh RR. Rima Aulia Fiska; Eka Destianti Edward; Eka Yunita Amna; Heru Noviat Herdata; Nora Sovira; Jufitriani Ismy
AcTion: Aceh Nutrition Journal Vol 10, No 3 (2025): September
Publisher : Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/action.v10i3.2486

Abstract

Frequent blood transfusions in children with beta-thalassemia major result in iron overload, leading to hemosiderosis in various body tissues, and impair the function of these organs, disrupting vitamin D metabolism, which contributes to osteoporosis and other morbidities, which are believed to be associated with hypocalcemia, which significantly affects growth. This study aimed to investigate the relationship between vitamin D and calcium status in children with β-thalassemia major at dr. Zainoel Abidin Public Hospital in Banda Aceh, Indonesia. Methods: An analytical observational study employed a cross-sectional design involving 40 children aged 2–18 years with a beta-thalassemia major attending the Children's Thalassemia Clinic at dr. Zainoel Abidin Public Hospital in Banda Aceh, Indonesia. from July to November, 2024. Categorical data were analyzed using the Spearman test, with a p-value of <0,05. Results, of the 40 subjects, 55% subjects were male, in 45% of subjects, there was Vitamin D deficiency, 25% was vitamin D insufficiency, hypocalcemia in 77,5% subjects. Among subjects with vitamin D deficiency, 94,4% also had hypocalcemia (r = 0,037, p = 0,017). In conclusion, there was a significant association between vitamin D and calcium status in children with beta-thalassemia major.
Nutritional status trajectories in cured and non-cured pediatric tuberculosis patients following six-month anti-TB treatment Zulfahlayya Zulkifli; Bakhtiar Bakhtiar; Eka Yunita Amna; Heru Noviat Herdata; Mulya Safri; Darnifayanti Darnifayanti
AcTion: Aceh Nutrition Journal Vol 11, No 2 (2026): June
Publisher : Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/action.v11i2.2923

Abstract

Pediatric tuberculosis (TB) remains a critical public health issue in Indonesia, with 809,000 new cases reported in 2023. Malnutrition is a common comorbidity; however, the nutritional trajectory that differentiates children who achieve clinical recovery from those who do not remains underexplored. This retrospective cohort study analyzed 102 children aged 2–18 years with pulmonary TB who were treated at RSUD dr. Zainoel Abidin, Banda Aceh, from January 2024 to January 2025. Patients with comorbidities and incomplete medical records were excluded. Nutritional status was assessed using the CDC 2000 Growth Charts at three time points: baseline, 2 months, and 6 months, and analyzed using Repeated Measures ANOVA (p<0.05). Among the participants, 96 (94.1%) recovered, whereas 6 (5.9%) did not. The mean body weight increased significantly from 21.9 kg at baseline to 25.0 kg at six months (p<0.001), with the proportion of children classified as well-nourished rising from 45.1% to 71.6%. Nutritional trajectories improved significantly over the treatment period (p<0.001), with more consistent gains observed in the recovery group. In conclusion, these findings indicate that six-month anti-tuberculosis therapy (ATT) is effective not only in resolving infection but also in enhancing the nutritional status of children. Monitoring nutritional trajectories may serve as a valuable prognostic indicator for evaluating treatment response and predicting clinical outcomes in pediatric TB.
Co-Authors Bakhtiar Bakhtiar Darnifayanti Darnifayanti Eka Destianti Edward Heru Noviat Herdata Heru Noviat Herdata Jufitriani Ismy Mulya Safri Nora Sovira RR. Rima Aulia Fiska Zulfahlayya Zulkifli