Corona virus 19 (Covid-19) is an infectious disease caused by a new type of corona virus. The cause of this new virus was unknown before it became an outbreak in Wuhan in December 2019. One way to overcome the Covid 19 infection is by administering a vaccine. Post-Immunization Adverse Events are medical events that are thought to be related to Covid-19 vaccination. Post-Immunization Adverse Events that appear after vaccination are much milder than if infected with Covid-19 or complications caused by the virus. Not everyone who is vaccinated against Covid-19 experiences post-vaccination side events.The aim of this research is to look at the follow-up events after Covid-19 vaccination. This research method is descriptive by collecting data using a questionnaire which will be filled in by the respondent. The research sample was people who had received the second Covid-19 booster vaccine and were undergoing outpatient treatment at the internal medicine clinic at the Tegalrejo Community Health Center, Yogyakarta. The total sample taken was 100 respondents and divided into the type of IndoVac vaccine, 1 respondent (1%); Sinopharm 2 respondents (2%); Pfizer and Astra each with 21 respondents (21%); Moderna 23 respondents (23%) and Sinovac 32 respondents (32%). Of the six types of vaccines, all types of vaccines experienced side effects after immunization such as pain at the injection site. For the Moderna and Pfizer vaccine types, the most people experienced fever, namely 11 respondents for each type of vaccine. The conclusion is that almost all types of Covid-19 vaccines given by the community at the Tegalrejo Community Health Center in the second booster experienced post-immunization side events such as pain at the injection site and fever