Anxiety is a psychological problem that is often experienced by teenagers, especially those who live in orphanages. This condition is influenced by various factors, including caregiver attention and social interaction. The aim of this research was to determine the relationship between caregiver attention and social interaction on anxiety levels in adolescents at the Al-Akbar Pekanbaru Orphanage. This research uses a quantitative design with a cross sectional approach and was carried out in December 2025. The population and sample in this study were all teenagers living at the Al-Akbar Pekanbaru Orphanage, totaling 45 respondents, using a total sampling technique. Data collection tools used caregiver attention questionnaires, social interactions, and the Hamilton Anxiety Rating Scale (HARS) instrument. Data analysis includes univariate and bivariate analysis using the Chi-Square test. The results showed that the majority of respondents had moderate category of caregiver attention (64.4%), medium category of social interaction (55.6%), and moderate level of anxiety (60.0%). The results of the bivariate test show that there is a significant relationship between caregiver attention and the level of adolescent anxiety (p-value = 0.000) and there is a significant relationship between social interaction and the level of adolescent anxiety (p-value = 0.000). The conclusion of the research is that there is a relationship between attention from orphanage caregivers and social interaction on anxiety among teenagers at the Al-Akbar Orphanage in Pekanbaru. Suggestions for the Al-Akbar Orphanage to improve the quality of caregivers' attention and social interaction activities as well as providing psychological assistance to reduce adolescent anxiety levels.Keywords: Anxiety, Caregiver Attention, Social Interaction, Adolescent