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All Journal Jurnal Respirologi Indonesia Respiratory Science
Wahju Aniwidyaningsih
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan General Hospital, Jakarta
Health Professions Medicine & Pharmacology

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Comparison Between Imprint Cytology and Histopathology Results in Pleural Effusion Cases Undergoing Pleuroscopy Wahju Aniwidyaningsih; Dian Prastiti Utami; Dicky Soehardiman; Mohammad Fahmi; Prasenohadi; Mia Elhidsi; Ginanjar Arum; Tina Reisa; Menaldi Rasmin; Ruth Emalian Sembiring; Romi Beginta; Eylin Rahardjo; Flora Dameria; Ni Putu Laksmi Ananda Martini
Jurnal Respirologi Indonesia Vol 46 No 2 (2026)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v46i2.1111

Abstract

Background: Pleuroscopy is a valuable minimally invasive procedure for evaluating undiagnosed pleural effusion. Rapid diagnosis of malignancy is often needed to reduce procedure time and patient discomfort, particularly when pleurodesis is planned. Imprint cytology is a quick and simple method, though underutilized in pleuroscopy practice in Indonesia. This study aimed to compare the diagnostic yield of imprint cytology and histopathology in pleural effusion cases undergoing pleuroscopy. Methods: This retrospective observational study was conducted from August to November 2024 and included patients with pleural effusion who underwent diagnostic pleuroscopy. Pleural biopsies were taken using forceps. Imprint cytology was performed by directly smearing the biopsy tissue onto slides, followed by staining. Histopathology was done using standard tissue processing. Results: Of the 25 patients who underwent pleuroscopy, 14 met the inclusion criteria. Pleuroscopic findings varied, with the most common being mass lesions (35.7%), followed by multiple nodules (21.4%) and sago-nodules (14.3%). Histopathology revealed malignancy in 10 patients (71.4%) and non-malignant in 4 (28.6%). Imprint cytology detected malignancy in 12 patients (85.7%) and non-malignant findings in 2 patients (14.3%). Conclusion: Imprint cytology offers a rapid and reliable diagnostic method during pleuroscopy, particularly in resource-limited settings. It may facilitate early detection of malignancy and support timely clinical decision-making.
Role of Interventional Pulmonology in Palliative Care Wahju Aniwidyaningsih; Ni Putu Laksmi Ananda Martini
Respiratory Science Vol. 6 No. 2 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i2.200

Abstract

Interventional pulmonology (IP) is a minimally invasive approach that plays a pivotal role in the evaluation and management of advanced thoracic diseases within palliative care. By integrating bronchoscopic and pleural techniques, IP provides effective symptom relief without the need for extensive surgical procedures or prolonged hospitalization. In malignant central airway obstruction, stenting, cryotherapy, and laser debulking offer rapid improvement in airflow and quality of life. For malignant pleural effusion, thoracentesis, pleurodesis, indwelling pleural catheters, and intrapleural fibrinolytic therapy for septated effusions provide safe and cost-effective strategies for symptom control. In selected cases of severe emphysema, bronchoscopic lung volume reduction using endobronchial valves improves lung mechanics and exercise capacity. In contrast, one-way endobronchial valves and spigots are valuable in managing persistent air leaks. With high procedural success rates and favorable safety profiles, IP is broadly applicable across diverse palliative respiratory conditions. Overall, IP provides a safe, effective, and patient-centered solution that complements standard palliative care, ensuring optimal quality of life while minimizing invasive burden.
Co-Authors Dian Prastiti Utami Dicky Soehardiman Eylin Rahardjo Flora Dameria Ginanjar Arum Menaldi Rasmin Mia Elhidsi Mohammad Fahmi Ni Putu Laksmi Ananda Martini Ni Putu Laksmi Ananda Martini Prasenohadi Romi Beginta Ruth Emalian Sembiring Tina Reisa