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All Journal Jurnal Sains Farmasi dan Kesehatan
Jesika Diah Pitaloka
Farmasi, Ilmu Kesehatan, Universitas Anwar Medika
Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary

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Literatur Review : Pengembangan Sediaan Suppositoria Dari Berbagai Ekstrak Nailah Mutiara Wahid; Jesika Diah Pitaloka; Ria Fitriyanti Putri; Rizka Tri Amanda Hidayat; Zahratul Humaidah; Alvan Andika Permadani; Dewi Rahmawati; Dzakiya Zhihrotulwida; M. Fithrul Mubarak
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4689

Abstract

Suppositories are one of the pharmaceutical dosage forms administered via the rectal or vaginal route and are considered an alternative drug delivery system for patients who cannot take oral medications. The development of herbal-based suppositories has increased due to their perceived safety, minimal side effects, and diverse pharmacological activities. This study aims to review the development of suppository dosage forms based on various plant extracts through a literature review method. The method used in this study is a literature review by collecting and analyzing ten scientific articles discussing the formulation and evaluation of suppositories derived from various plant extracts such as Aloe vera, Amaranthus spinosus, Piper betle, Garcinia mangostana, Areca catechu, Peperomia pellucida, senna, Cynodon dactylon, and Cassia fistula. The analyzed parameters include formulation methods, types of bases used, physical evaluation results, and pharmacological activities. The results show that the fusion (moulding) method is the most commonly used technique in suppository preparation. The bases used include cocoa butter (oleum cacao), polyethylene glycol (PEG), and glycerinated gelatin, each influencing the physical characteristics of the suppositories such as melting point, melting time, hardness, and weight uniformity. In addition, various plant extracts demonstrate different pharmacological activities, including anti-inflammatory, antifungal, antibacterial, laxative, and anthelmintic effects. In conclusion, the development of herbal-based suppositories has significant potential as an effective and innovative drug delivery system. However, further studies, particularly stability testing and clinical trials, are required to ensure their safety and therapeutic effectiveness.
Peran Farmasi Klinis Pada Rekonsiliasi Untuk Mengurangi Ketidaksesuaian Pengobatan Nailah Mutiara Wahid; Nungki Hatit Isafani; Nisful Lailatun Nadiroh; Dwi Roisiyah; Ria Fitriyanti Putri; Jesika Diah Pitaloka; Meiva Shafa Herdini; Iftitah Nakhlah Sani; Wishnu Eka Adiwinata; Bella Fevi Aristia; Alfu Laila; Eka Putri Nurhidayah; Arya Sigit Kharismawan
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4846

Abstract

Medication reconciliation is an essential process in pharmaceutical care aimed at preventing medication discrepancies that may lead to medication errors and compromise patient safety. Clinical pharmacy plays a strategic role in this process through verifying, identifying, and clarifying patients’ medication histories. This review aims to analyze the role of clinical pharmacists in medication reconciliation to reduce medication discrepancies based on various research findings. This study used a literature review method by examining 10 journals related to medication reconciliation, medication discrepancies, and the role of clinical pharmacists in hospital settings. The results show that medication discrepancies are still frequently found at different stages of care, particularly during patient transitions. The most common discrepancies include omitted medications, dose differences, therapeutic duplication, and undocumented medication changes. The involvement of clinical pharmacists has been shown to reduce discrepancies through medication verification, interprofessional communication, and support from information systems and complete documentation. In conclusion, clinical pharmacists play an important role in improving the effectiveness of medication reconciliation and reducing medication discrepancies. Strengthening the role of clinical pharmacists, improving documentation systems, and enhancing interprofessional collaboration are essential to improve patient safety.
Co-Authors Alfu Laila Alvan Andika Permadani Arya Sigit Kharismawan Bella Fevi Aristia Dewi Rahmawati Dwi Roisiyah Dzakiya Zhihrotulwida Eka Putri Nurhidayah Iftitah Nakhlah Sani M. Fithrul Mubarak Meiva Shafa Herdini Nailah Mutiara Wahid Nisful Lailatun Nadiroh Nungki Hatit Isafani Ria Fitriyanti Putri Rizka Tri Amanda Hidayat Wishnu Eka Adiwinata Zahratul Humaidah