Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Jurnal Ilmu Psikologi dan Kesehatan
Linda Khafidho Nur Khasanah
Fakultas Ilmu Kesehatan, Universitas Anwar Medika
Health Professions Immunology & microbiology Library & Information Science Neuroscience Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Tinjauan Metode Granulasi Basah dalam Formulasi Tablet Effervescent Linda Khafidho Nur Khasanah; Cholifatus Shahroh; Aprillia Cahyaningtyas; Selviana Eka Rahma Nilasari; Rimba Setia Buana Khanza Arifin; Dewi Rahmawati
Jurnal Ilmu Psikologi dan Kesehatan | E-ISSN : 3063-1467 Vol. 3 No. 2 (2026): Juli - September
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jipk.v3i2.2213

Abstract

Effervescent tablets are one of the pharmaceutical dosage forms widely developed due to their ability to enhance dissolution rate, bioavailability, and patient compliance, especially for individuals who have difficulty swallowing conventional tablets. In the formulation of effervescent tablets, an appropriate powder processing method is required to produce granules with optimal physical properties, one of which is the wet granulation method. This study aims to comprehensively review the role of wet granulation in the formulation of effervescent tablets based on literature from various scientific journals. The method used in this study is a Systematic Literature Review (SLR), with data sources obtained from electronic databases such as Google Scholar, PubMed, and ScienceDirect within the last 5–10 years. The results of the review indicate that wet granulation improves powder flowability, compressibility, and content uniformity. In addition, this method enhances the mechanical strength of tablets and improves dissolution characteristics, resulting in better quality effervescent tablets. However, wet granulation also has limitations, particularly its sensitivity to moisture, which may trigger premature effervescent reactions, as well as its relatively complex manufacturing process. In conclusion, wet granulation is an effective method for the formulation of effervescent tablets when process parameters and material selection are properly optimized.
Co-Authors Aprillia Cahyaningtyas Cholifatus Shahroh Dewi Rahmawati Rimba Setia Buana Khanza Arifin Selviana Eka Rahma Nilasari