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Nur Mahdi
Program Studi Farmasi Fakultas MIPA Universitas Lambung Mangkurat Banjarbaru, Kalimantan Selatan
Health Professions Nursing Public Health

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FORMULASI DAN UJI EFEKTIVITAS SEDIAAN LOTION ANTIOKSIDAN DARI EKSTRAK ETANOL DAUN SUNGKAI (Peronema Canescens Jack.) Nur Syamsiah; Nur Mahdi; Ani Agustina
Journal of Pharmacology Experiment and Pharmaceutical Technology Vol. 2 No. 2 (2026): JPEPT
Publisher : DSM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64015/jpept.v2i1.4

Abstract

Perawatan kulit penting untuk melindungi kulit dari sinar ultraviolet, oleh karena itu kulit harus selalu dijaga kebersihan, kesehatan, dan perawatannya. Salah satu perawatan kulit yang umum digunakan untuk tubuh adalah lotion yang baik untuk kulit dan dapat melindungi kulit dari sinar ultraviolet dan radikal bebas. Tujuan penelitian ini adalah untuk menentukan aktivitas antioksidan ekstrak etanol daun sungkai (Peronema Canescens jack) menggunakan metode DPPH dengan konsentrasi 15 ppm, 30 ppm, 45 ppm, 60 ppm, dan 75 ppm. Nilai IC50 yang diperoleh adalah 13,661 ppm. Penelitian dimulai dengan pembuatan simplisia kemudian ekstrak yang diperoleh diuji untuk skrining fitokimia dan uji aktivitas antioksidan dan dilanjutkan dengan pembuatan formulasi lotion yang dibuat dengan empat konsentrasi, yaitu F0 (Basis), F1 (0,0015%), F2 (0,003%), dan F3 (0,0045%). Lotion tersebut kemudian diuji untuk evaluasi stabilitas fisik melalui uji organoleptik, homogenitas, pH, dan dispersibilitas. Hasil pengujian antioksidan menggunakan metode DPPH dengan konsentrasi 15 ppm, 30 ppm, 45 ppm, 60 ppm dan 75 ppm memperoleh hasil IC50 dari ekstrak etanol daun sungkai sebesar 13,661 ppm (sangat kuat). Sedangkan hasil uji evaluasi penambahan ekstrak etanol daun sungkai pada preparat tersebut terdapat perbedaan pada uji adhesi. Berdasarkan hasil uji stabilitas fisik, dapat dilihat bahwa formula F1 adalah formula terbaik, dilihat dari hasil uji adhesi yang menunjukkan bahwa formula F1 lebih baik daripada preparat lainnya, sedangkan hasil uji lainnya tidak signifikan
FORMULASI DAN EVALUASI STABILITAS FISIK SEDIAAN KRIM PELEMBAB WAJAH MENGANDUNG EKSTRAK ETANOL DAUN KELAPA SAWIT (Elaeis guineensis. Jacq.) Halimatus Sa'diah; Ani Agustina; Nur Mahdi; Deni Setiawan
Journal of Pharmacology Experiment and Pharmaceutical Technology Vol. 2 No. 2 (2026): JPEPT
Publisher : DSM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64015/jpept.v2i2.5

Abstract

Ethanol extract of oil palm leaves (Elaeis guineensis Jacq.) is known to have antioxidant activity that has the potential to be developed as an active ingredient in facial moisturizing cosmetics. This study aims to formulate ethanol extract of oil palm leaves into a facial moisturizing cream preparation and evaluate the physical characteristics and stability of the preparation. The study was conducted experimentally in a laboratory with four formulas, namely F0 (0%), FI (0.0133%), F2 (0.0266%), F3 (0.0399%) of oil palm leaf extract. Evaluation of the preparation included organoleptic tests, homogeneity, pH, spreadability and viscosity during 28 days of storage at room temperature. The results showed that all formulas were semi-solid, homogeneous, and organoleptically stable without changes in color, odor, or phase separation during storage. The pH value of all formulas was in the range of 6-7 cm and the viscosity met the requirements of a cream preparation. Statistical analysis showed no significant differences in spreadability and viscosity between the formulas (p>0.05). Based on the research results, the ethanol extract of oil palm leaves can be formulated into a facial moisturizing cream with good characteristics and stability.
NARRATIVE REVIEW : KAJIAN KANDUNGAN SENYAWA FLAVONOID DAN FENOLIK PADA TANAMAN MANGGA KASTURI (Mangifera Casturi Kosterm.): NARRATIVE REVIEW: STUDY OF FLAVONOID AND PHENOLIC COMPOUND CONTENT IN MANGIFERA CASTURI MANGO PLANTS (Mangifera Casturi Kosterm.) Eka Purnama Sari; Indah Taufiqoh; Reski Tiku Sarampang; Yasmin Shopiah; Nur Mahdi
Journal of Pharmacology Experiment and Pharmaceutical Technology Vol. 2 No. 1 (2026): JPEPT
Publisher : DSM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64015/jpept.v2i1.9

Abstract

Kasturi mango, also known as Mangifera casturi Kosterm. is a plant endemic to Kalimantan that has great potential as a source of bioactive compounds, especially flavonoids and phenolics. These two compounds are known to perform various biological functions, including antioxidants, antibacterials, and anti-inflammatory. The aim of this study was to study and summarize scientific evidence on the content of flavonoids and phenolics in various parts of the kasturi mango plant. The method used included understanding scientific literature from 2013–2025 from bold databases such as PubMed and Google Scholar. Inclusion and exclusion criteria were used to select the collected articles; the result was 30 articles that were evaluated descriptively. The results showed that flavonoids and phenolics were found in the leaves, bark, fruit peel, seeds, and fruit of kasturi mango through qualitative and quantitative analyses. The leaves are the part of the plant with the highest flavonoid and phenolic content. Thus, kasturi mango has great potential to be developed as a source of natural antioxidants and raw materials for natural-based health products.
Co-Authors Ani Agustina Deni Setiawan Eka Purnama Sari Halimatus Sa'diah Indah Taufiqoh Nur Syamsiah Reski Tiku Sarampang Yasmin Shopiah