Introduction: Psoriasis is a chronic inflammatory skin disease often accompanied by significant psychosocial impacts. Patients frequently report body image disturbances, embarrassment, social stigma, and reduced social participation, which ultimately contribute to a diminished quality of life. This literature review aims to synthesize evidence on the effectiveness of Cognitive Behavioral Therapy in improving the quality of life of patients with psoriasis from a psychological perspective. Methods: This literature review was conducted by identifying the PICO framework (Population/Patient, Intervention, Comparison, Outcome). A literature search was conducted from 2025 to 2026 following the PRISMA 2020 guidelines and the Joanna Briggs Institute (JBI) methodology across several scientific databases, including Wiley Online Library, ScienceDirect, and Google Scholar. Inclusion criteria comprised articles published within the last six years, focusing on CBT interventions and quality of life in patients with psoriasis, and available in full text. Results: The literature review identified two main themes. The first theme highlights the role of CBT in reducing psychological distress, including anxiety, depression, emotional stress, and negative body image, as a primary pathway to improving quality of life. The second theme emphasizes the modification of maladaptive behaviors into adaptive coping strategies, resulting in improved social functioning, daily activities, and interpersonal relationships. Recommendations: Cognitive Behavioral Therapy should be considered as an adjunct intervention in the comprehensive management of psoriasis to improve patients’ psychological well-being and quality of life. Further research with larger sample sizes and long-term follow-up is recommended to strengthen evidence regarding its sustained effectiveness across diverse patient populations. Â