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All Journal Jurnal Farmasi Ma Chung: Sains, Teknologi, dan Klinis Komunitas Medimuh : Jurnal Kesehatan Muhammadiyah Medimuh : Jurnal Kesehatan Muhammadiyah
Renny Amelia
Universitas Muhammadiyah Ahmad Dahlan Cirebon
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Formulation and Antioxidant Activity Evaluation of Aloe Vera Gel Face Mist Using the DPPH Method Renny Amelia
Jurnal Farmasi Ma Chung: Sains, Teknologi, dan Klinis Komunitas Vol. 4 No. 1 (2026): Jurnal Farmasi Ma Chung: Sains, Teknologi, dan Klinis Komunitas
Publisher : Program Studi Farmasi, Universitas Ma Chung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33479/jfmc.v4i1.116

Abstract

Skin damage may be caused by metabolic waste products, combustion processes, and free radicals, which require antioxidants both systemically and locally. One source of antioxidants can be obtained from aloe vera gel extract, which contains compounds such as aloin, aloesin, aloe-emodin, and tannins. This study aimed to determine whether aloe vera gel extract could be formulated into a face mist preparation and to evaluate the antioxidant activity of the resulting face mist formulation. One of the benefits of face mist preparations is their ability to refresh and moisturize facial skin while also providing protection against ultraviolet (UV) radiation-induced damage.The aloe vera gel extract face mist formulations were prepared in varying concentrations of 30%, 35%, and 40%, followed by evaluations including organoleptic testing, pH testing, spreadability testing, homogeneity testing, and viscosity testing. Antioxidant activity was evaluated using the DPPH method with a UV-Vis spectrophotometer, using vitamin C as the reference standard. The results demonstrated that aloe vera gel extract could be successfully formulated into face mist preparations at concentrations of 30%, 35%, and 40%. Based on the evaluation results, including organoleptic properties, homogeneity, specific gravity, viscosity, and spreadability, all formulations met the required standards for face mist preparations. The antioxidant activity test results showed that the 30%, 35%, and 40% aloe vera gel extract face mist formulations were classified as strong antioxidants.
Formulation and Antioxidant Activity Evaluation of Aloe Vera Gel Face Mist Using the DPPH Method Renny Amelia
Jurnal Farmasi Ma Chung: Sains, Teknologi, dan Klinis Komunitas Vol. 4 No. 1 (2026): Jurnal Farmasi Ma Chung: Sains, Teknologi, dan Klinis Komunitas
Publisher : Program Studi Farmasi, Universitas Ma Chung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33479/jfmc.v4i1.116

Abstract

Skin damage may be caused by metabolic waste products, combustion processes, and free radicals, which require antioxidants both systemically and locally. One source of antioxidants can be obtained from aloe vera gel extract, which contains compounds such as aloin, aloesin, aloe-emodin, and tannins. This study aimed to determine whether aloe vera gel extract could be formulated into a face mist preparation and to evaluate the antioxidant activity of the resulting face mist formulation. One of the benefits of face mist preparations is their ability to refresh and moisturize facial skin while also providing protection against ultraviolet (UV) radiation-induced damage.The aloe vera gel extract face mist formulations were prepared in varying concentrations of 30%, 35%, and 40%, followed by evaluations including organoleptic testing, pH testing, spreadability testing, homogeneity testing, and viscosity testing. Antioxidant activity was evaluated using the DPPH method with a UV-Vis spectrophotometer, using vitamin C as the reference standard. The results demonstrated that aloe vera gel extract could be successfully formulated into face mist preparations at concentrations of 30%, 35%, and 40%. Based on the evaluation results, including organoleptic properties, homogeneity, specific gravity, viscosity, and spreadability, all formulations met the required standards for face mist preparations. The antioxidant activity test results showed that the 30%, 35%, and 40% aloe vera gel extract face mist formulations were classified as strong antioxidants.
Aktivitas Antijamur Hair Tonic Ekstrak Daun Bunga Sepatu Terhadap Pityrosporum Ovale: Studi Formulasi Dan Evaluasi Renny Amelia; Ghany Ahadi; Deni Firmansyah; Tomi
Medimuh : Jurnal Kesehatan Muhammadiyah Vol 7 No 1 (2026)
Publisher : Universitas Muhammadiyah Ahmad Dahlan Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/mh.v7i1.2053

Abstract

Kondisi kulit kepala seperti ketombe dan produksi sebum berlebih dapat mengganggu pertumbuhan rambut. Jamur Malassezia furfur sebagai penyebab utama ketombe diketahui tumbuh optimal pada kulit kepala berminyak. Penelitian klinis pada Sebagian besar orang meujuka keluhan kerontokan rambut. Hair tonic merupakan salah satu sediaan kosmetik yang berpotensi digunakan untuk mengatasi permasalahan rambut dan kulit kepala. Daun kembang sepatu (Hibiscus rosa-sinensis L.) mengandung senyawa antimikroba yang berpotensi menghambat pertumbuhan mikroorganisme. Penelitian ini bertujuan untuk memformulasikan hair tonic antiketombe yang mengandung ekstrak daun kembang sepatu pada konsentrasi 5%, 7%, dan 10%, serta mengevaluasi aktivitas antijamurnya terhadap Pityrosporum ovale. Sediaan hair tonic dibuat dengan variasi konsentrasi ekstrak 5%, 7%, dan 10%, kemudian dilakukan evaluasi mutu fisik yang meliputi uji organoleptik, homogenitas, pH, bobot jenis, dan viskositas. Aktivitas antijamur diuji menggunakan metode sumuran pada media Potato Dextrose Agar (PDA). Daya hambat ditentukan berdasarkan pengukuran diameter zona bening di sekitar sumuran menggunakan jangka sorong. Hasil penelitian menunjukkan bahwa seluruh formula memenuhi persyaratan mutu fisik berdasarkan pengamatan organoleptik, homogenitas, pH, bobot jenis, dan viskositas. Selain itu, sediaan hair tonic yang mengandung ekstrak daun kembang sepatu memiliki kemampuan menghambat pertumbuhan Pityrosporum ovale, meskipun aktivitas antijamur yang dihasilkan masih tergolong lemah. Dengan demikian, ekstrak daun kembang sepatu berpotensi dikembangkan sebagai bahan aktif dalam formulasi hair tonic antiketombe Kata kunci : Ekstrak daun Hibiscus, Hair Tonic, uji daya hambat, Pityrosporum Ovale
Aktivitas Antijamur Hair Tonic Ekstrak Daun Bunga Sepatu Terhadap Pityrosporum Ovale: Studi Formulasi Dan Evaluasi Renny Amelia; Ghany Ahadi; Deni Firmansyah; Tomi
Medimuh : Jurnal Kesehatan Muhammadiyah Vol 7 No 1 (2026)
Publisher : Universitas Muhammadiyah Ahmad Dahlan Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/mh.v7i1.2053

Abstract

Kondisi kulit kepala seperti ketombe dan produksi sebum berlebih dapat mengganggu pertumbuhan rambut. Jamur Malassezia furfur sebagai penyebab utama ketombe diketahui tumbuh optimal pada kulit kepala berminyak. Penelitian klinis pada Sebagian besar orang meujuka keluhan kerontokan rambut. Hair tonic merupakan salah satu sediaan kosmetik yang berpotensi digunakan untuk mengatasi permasalahan rambut dan kulit kepala. Daun kembang sepatu (Hibiscus rosa-sinensis L.) mengandung senyawa antimikroba yang berpotensi menghambat pertumbuhan mikroorganisme. Penelitian ini bertujuan untuk memformulasikan hair tonic antiketombe yang mengandung ekstrak daun kembang sepatu pada konsentrasi 5%, 7%, dan 10%, serta mengevaluasi aktivitas antijamurnya terhadap Pityrosporum ovale. Sediaan hair tonic dibuat dengan variasi konsentrasi ekstrak 5%, 7%, dan 10%, kemudian dilakukan evaluasi mutu fisik yang meliputi uji organoleptik, homogenitas, pH, bobot jenis, dan viskositas. Aktivitas antijamur diuji menggunakan metode sumuran pada media Potato Dextrose Agar (PDA). Daya hambat ditentukan berdasarkan pengukuran diameter zona bening di sekitar sumuran menggunakan jangka sorong. Hasil penelitian menunjukkan bahwa seluruh formula memenuhi persyaratan mutu fisik berdasarkan pengamatan organoleptik, homogenitas, pH, bobot jenis, dan viskositas. Selain itu, sediaan hair tonic yang mengandung ekstrak daun kembang sepatu memiliki kemampuan menghambat pertumbuhan Pityrosporum ovale, meskipun aktivitas antijamur yang dihasilkan masih tergolong lemah. Dengan demikian, ekstrak daun kembang sepatu berpotensi dikembangkan sebagai bahan aktif dalam formulasi hair tonic antiketombe Kata kunci : Ekstrak daun Hibiscus, Hair Tonic, uji daya hambat, Pityrosporum Ovale
Co-Authors Deni Firmansyah Ghany Ahadi Tomi